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1-Deoxynojirimycin (CID 29435) - Compound BioActivity Data
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BioActivity Outcomes:
Active(102)
 
 
Inactive(43)
 
 
Inconclusive(5)
 
 
Unspecified(149)
 
 
Top Targets:
GH31 MGAM SI..(30)
 
 
 
 
Glyco hydro 3..(9)
 
 
Glyco hydro 3..(7)
 
 
 
BGL(6)
 
 
 
BglB(3)
 
 
 
BioAssay Types:
Literature(236)
 
 
 
 
Confirmatory(45)
 
 
 
 
 
Screening(6)
 
 
BioActivity Types:
IC50(132)
 
 
 
 
Potency(29)
 
 
 
 
Ki(21)
 
 
 
Kd(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 293    Data Row: 299   Total Pages: 15   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103278185]
Ki 0.014Competitive Inhibition constant on rice alpha Glucosidase at pH 6.0 [AID220747, Type: confirmatory]
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2
[SID103278185]
Ki 0.024Tested in vitro for the inhibition constant against rat small intestinal sucrase [AID208987, Type: confirmatory]
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3
[SID103278185]
IC50 0.03Inhibition of rice alpha glucosidase [AID437996, Type: Literature]
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4
[SID103278185]
IC50 0.03Inhibition of rice alpha-glucosidase assessed as production of D-glucose using maltose as substrate after 10 to 30 mins by spectrophotometry [AID613055, Type: Literature]
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5
[SID103278185]
IC50 0.03Inhibitory concentration against rice alpha-glucosidase [AID240928, Type: Literature]
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6
[SID26752140]
Potency 0.0366Confirmation of Inhibitors and Activators of Purified Human alpha-Glucosidase Using an Alternate Red Fluorescent Susbtrate [AID2110, Type: confirmatory]lysosomal alpha-glucosidase preproprotein [Homo sapiens] [gi:119393891]
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7
[SID26752140]
Potency 0.0366Confirmation of Inhibitors and Activators of Purified Human alpha-Glucosidase [AID2115, Type: confirmatory]lysosomal alpha-glucosidase preproprotein [Homo sapiens] [gi:119393891]
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8
[SID103278185]
IC50 0.04Inhibitory concentration against human alpha-glucosidase [AID240862, Type: Literature]Maltase-glucoamylase, intestinal [gi:215274260]
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9
[SID103278185]
IC50 0.05Inhibitory activity against alpha-Glucosidase from rice [AID240826, Type: Literature]
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10
[SID103278185]
IC50 0.05Inhibition of rice alpha-glucosidase assessed as D-glucose release after 10 mins by Glucose B-test [AID397842, Type: Literature]
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11
[SID26752140]
Potency 0.0517Confirmation of Inhibitors and Activators of Human alpha-Glucosidase From Spleen Homogenate [AID2113, Type: confirmatory]lysosomal alpha-glucosidase preproprotein [Homo sapiens] [gi:119393891]
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12
[SID103278185]
IC50 0.06Inhibition of maltase in human Caco-2 cell model system after 2 hrs [AID342811, Type: Literature]Lysosomal alpha-glucosidase [gi:317373572]
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13
[SID26752140]
Potency 0.0651Confirmation of Inhibitors and Activators of Human alpha-Glucosidase From Spleen Homogenate Using an Alternate Red Fluorescent Susbtrate [AID2111, Type: confirmatory]lysosomal alpha-glucosidase preproprotein [Homo sapiens] [gi:119393891]
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14
[SID103278185]
IC50 0.13Inhibition of rat intestinal brush border membrane maltase [AID342793, Type: Literature]Lysosomal alpha-glucosidase [gi:81885339]
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15
[SID103278185]
Ki 0.15Tested in vitro for the inhibition constant against human lysosomal alpha-glucosidase [AID37275, Type: confirmatory]
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16
[SID103278185]
Ki 0.16Competitive Inhibition constant on rice alpha Glucosidase at pH 5.0 [AID220746, Type: confirmatory]
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17
[SID103278185]
IC50 0.16Inhibition of rat intestinal brush border membrane isomaltase [AID342795, Type: Literature]Sucrase-isomaltase, intestinal [gi:1351132]
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18
[SID103278185]
IC50 0.19Inhibition of rabbit muscle amylo-1,6-glucosidase [AID342805, Type: Literature]Glycogen debranching enzyme [gi:544379]
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19
[SID103278185]
IC50 0.21Inhibition of rat intestinal brush border membrane sucrase [AID342797, Type: Literature]Sucrase-isomaltase, intestinal [gi:1351132]
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20
[SID103278185]
IC50 0.21Inhibition of rat intestinal sucrase using sucrose as substrate [AID711102, Type: Literature]Sucrase-isomaltase, intestinal [gi:1351132]
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