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BioActivity Data for Compound ISOXATHION (CID 29307)

BioActivity Outcomes:
Active(6)
 
 
Inactive(71)
 
 
Inconclusive(16)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
 
NR LBD AR(7)
 
 
 
NR LBD ER(7)
 
 
 
 
NR LBD VDR(4)
 
 
 
NR LBD Fxr(4)
 
 
 
BioAssay Types:
Confirmatory(62)
 
 
 
 
Summary(24)
 
 
 
 
Literature(2)
 
 
Screening(1)
 
 
BioActivity Types:
Potency(80)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 93    Data Row: 93   Total Pages: 5   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144212526]
Potency-Replicate_1 3.4376qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
View
2
[SID144212526]
AhR Potency (uM) 5.8829qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
View
3
[SID144212526]
Potency-Replicate_1 61.1306qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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4
[SID144212526]
Potency-Replicate_1 68.5896qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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5
[SID144212526]
Potency-Replicate_1 68.5896qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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6
[SID144212526]
Potency-Replicate_1 68.5896qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
View
7
[SID144212526]
Potency-Replicate_1 10.8707qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 - cell viability [AID651634, Type: confirmatory]
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8
[SID144212526]
Potency-Replicate_1 68.5896qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
View
9
[SID144212526]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway: Summary [AID743053, Type: summary]AR protein [Homo sapiens] [gi:124375976]
View
10
[SID92151251]
A screen for compounds that inhibit the bacterial siderophore biosynthetic enzyme BasE [AID485350, Type: screening]enterobactin synthase subunit E [Acinetobacter baumannii ATCC 17978] [gi:126642418]
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11
[SID92151251]
A screen for compounds that inhibit the activity of Staphylococcus aureus DNA helicase [AID485395, Type: other]replicative DNA helicase [Staphylococcus aureus subsp. aureus JH1] [gi:150392496]
View
12
[SID144212526]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway [AID743212, Type: confirmatory]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
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13
[SID92151251]
A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities [AID588519, Type: Literature]Chain A, Poliovirus Polymerase With Gtp [gi:52695378]
View
14
[SID92151251]
A screen for compounds that inhibit the bacterial siderophore biosynthetic enzyme MbtI [AID493033, Type: other]Isochorismate synthase/isochorismate-pyruvate lyase mbtI [gi:81706979]
View
15
[SID144212526]
Potency-Replicate_1 qHTS assay to identify aromatase inhibitors [AID743083, Type: confirmatory]cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a [Homo sapiens] [gi:119597822]
View
16
[SID144212526]
qHTS assay to identify aromatase inhibitors: Summary [AID743139, Type: summary]cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a [Homo sapiens] [gi:119597822]
View
17
[SID144212526]
Potency-Replicate_1 qHTS assay for small molecule activators of the heat shock response signaling pathway [AID743210, Type: confirmatory]heat shock protein beta-1 [Homo sapiens] [gi:4504517]
View
18
[SID144212526]
Ratio Potency (uM) qHTS assay for small molecule activators of the heat shock response signaling pathway: Summary [AID743228, Type: summary]heat shock protein beta-1 [Homo sapiens] [gi:4504517]
View
19
[SID92151251]
A screen for compounds that inhibit replication of Vibrio cholerae chromosome II [AID504770, Type: other]hypothetical protein VC_A0002 [Vibrio cholerae O1 biovar El Tor str. N16961] [gi:9657380]
View
20
[SID92151251]
A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis [AID540299, Type: Literature]1,4-dihydroxy-2-naphthoyl-CoA synthase [Mycobacterium tuberculosis H37Rv] [gi:15607688]
View