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Cyclophosphamide (CID 2907) - Compound BioActivity Data
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BioActivity Outcomes:
Active(85)
 
 
Inactive(363)
 
 
Inconclusive(13)
 
 
Unspecified(2198)
 
 
Top Targets:
7TM GPCR Srx(22)
 
 
 
p450(18)
 
 
 
 
7TM GPCR Srsx(16)
 
 
 
NAD binding 8(6)
 
 
 
Pyr redox dim(5)
 
 
 
BioAssay Types:
Confirmatory(399)
 
 
 
 
 
Literature(340)
 
 
 
 
 
Screening(13)
 
 
Summary(1)
 
 
BioActivity Types:
Potency(189)
 
 
 
 
 
IC50(130)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 2605    Data Row: 2659   Total Pages: 133   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID90341534]
Potency 0.006qHTS Validation Assay for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails [AID488953, Type: confirmatory]chromobox protein homolog 1 [Homo sapiens] [gi:187960037]
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2
[SID103171472]
IC50 8.79Cytotoxicity against human HL60 cells by MTT assay [AID526308, Type: Literature]
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3
[SID90341534]
Potency 17.7828qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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4
[SID103171472]
LC50 37.6In vitro cytotoxicity was evaluated in mouse embryo BALB/c 3T3 cells [AID3372, Type: Literature]
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5
[SID103171472]
IC50 37.6In vitro cytotoxicity against BALB/c 3T3 cells [AID41567, Type: Literature]
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6
[SID103171472]
LC50 37.6In vitro cytotoxicity in BALB/c3T3 mouse embryo fibroblasts. [AID41575, Type: Literature]
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7
[SID87150]
NCI In Vivo Anticancer Drug Screen. Data for tumor model P388 Leukemia (intracerebral) in CD2F1 (CDF1) mice [AID334, Type: other]
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8
[SID87150]
NCI In Vivo Anticancer Drug Screen. Data for tumor model P388 Leukemia resistant to Vincristine; NSC 67574 (intraperitoneal) in B6D2F1 (BDF1) mice [AID336, Type: other]
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9
[SID87150]
NCI In Vivo Anticancer Drug Screen. Data for tumor model P388 Leukemia resistant to A Terephthalanilide; NSC 38280 (intraperitoneal) in B6D2F1 (BDF1) mice [AID338, Type: other]
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10
[SID87150]
NCI In Vivo Anticancer Drug Screen. Data for tumor model Reticulum Cell Sarcoma (Kelley Mouse) (intraperitoneal) in CD2F1 (CDF1) mice [AID340, Type: other]
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11
[SID87150]
NCI In Vivo Anticancer Drug Screen. Data for tumor model Lieberman Plasma Cell No. 1 (LPC-1) (intraperitoneal) in unknown mice [AID344, Type: other]
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12
[SID141705]
NCI In Vivo Anticancer Drug Screen. Data for tumor model L1210 Leukemia (intraperitoneal) in CD2F1 (CDF1) mice [AID256, Type: other]
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13
[SID141706]
NCI In Vivo Anticancer Drug Screen. Data for tumor model L1210 Leukemia (intraperitoneal) in CD2F1 (CDF1) mice [AID256, Type: other]
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14
[SID48413505]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
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15
[SID103171472]
Antitumor activity in human U87 MG cells xenografted mouse at 80 mg/kg, iv administered in Q2D x 5 schedule [AID408369, Type: Literature]
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16
[SID103171472]
Immunosuppressive activity against MAV-1 infected BALB/c mouse assessed as leukopenia in lymph node at 100 mg/kg, ip treated 8 days before infection measured 3 days post infection by flow cytometry [AID542219, Type: Literature]
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17
[SID48413505]
DSSTox (CPDBAS) Carcinogenic Potency Database Salmonella Mutagenicity [AID1194, Type: other]
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18
[SID48413505]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Mouse Bioassay Results [AID1199, Type: other]
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19
[SID48413505]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results [AID1205, Type: other]
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20
[SID48413505]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
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