Bookmark and Share
Cyclophosphamide (CID 2907) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(90)
 
 
Inactive(363)
 
 
Inconclusive(13)
 
 
Unspecified(2241)
 
 
Top Targets:
7tm 4(37)
 
 
 
p450(18)
 
 
 
 
NAD binding 8(6)
 
 
 
Pyr redox dim(5)
 
 
 
ANK(4)
 
 
BioAssay Types:
Confirmatory(404)
 
 
 
 
 
Literature(359)
 
 
 
 
 
Screening(13)
 
 
Summary(1)
 
 
BioActivity Types:
Potency(189)
 
 
 
 
 
IC50(135)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 2653    Data Row: 2707   Total Pages: 136   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID90341534]
Potency 0.006qHTS Validation Assay for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails [AID488953, Type: confirmatory]chromobox protein homolog 1 [Homo sapiens] [gi:187960037]
View
2
[SID103171472]
IC50 0.09Cytotoxicity against Homo sapiens (human) MDA-MB-231 cells after 48 hr by MTT assay [AID1085426, Type: confirmatory]
View
3
[SID103171472]
IC50 0.15Cytotoxicity against Homo sapiens (human) K562 cells after 48 hr by MTT assay [AID1085429, Type: confirmatory]
View
4
[SID103171472]
IC50 0.153Antiproliferative activity against Homo sapiens (human) K562 cells after 48 hr by MTT assay [AID1083866, Type: confirmatory]
View
5
[SID103171472]
IC50 0.16Cytotoxicity against Homo sapiens (human) MCF7 cells after 48 hr by trypan blue assay [AID1095201, Type: confirmatory]
View
6
[SID103171472]
IC50 0.24Cytotoxicity against Homo sapiens (human) HepG2 cells after 48 hr by MTT assay [AID1085427, Type: confirmatory]
View
7
[SID103171472]
IC50 8.79Cytotoxicity against human HL60 cells by MTT assay [AID526308, Type: Literature]
View
8
[SID90341534]
Potency 17.7828qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
View
9
[SID103171472]
LC50 37.6In vitro cytotoxicity was evaluated in mouse embryo BALB/c 3T3 cells [AID3372, Type: Literature]
View
10
[SID103171472]
IC50 37.6In vitro cytotoxicity against BALB/c 3T3 cells [AID41567, Type: Literature]
View
11
[SID103171472]
LC50 37.6In vitro cytotoxicity in BALB/c3T3 mouse embryo fibroblasts. [AID41575, Type: Literature]
View
12
[SID48413505]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
View
13
[SID103171472]
Antitumor activity in human U87 MG cells xenografted mouse at 80 mg/kg, iv administered in Q2D x 5 schedule [AID408369, Type: Literature]
View
14
[SID103171472]
Induction of Escherichia coli pBluescript 2 KS+ DNA cleavage at 10 mM by gel electrophoresis [AID408577, Type: Literature]
View
15
[SID103171472]
Inhibition of human CYP1A2 assessed as ratio of IC50 in absence of NADPH to IC50 for presence of NADPH using ethoxyresorufin as substrate after 30 mins [AID678712, Type: Literature]Cytochrome P450 1A2 [gi:117144]
View
16
[SID87150]
NCI In Vivo Anticancer Drug Screen. Data for tumor model P335 Leukemia (intraperitoneal) in B6D2F1 (BDF1) mice [AID224, Type: other]
View
17
[SID87150]
NCI In Vivo Anticancer Drug Screen. Data for tumor model Ependymoblastoma (intracerebral) in B6C3F1 mice [AID226, Type: other]
View
18
[SID87150]
NCI In Vivo Anticancer Drug Screen. Data for tumor model Friend Virus Leukemia (Solid) (subcutaneous) in B6D2F1 (BDF1) mice [AID228, Type: other]
View
19
[SID87150]
NCI In Vivo Anticancer Drug Screen. Data for tumor model Lymphosarcoma Gardner 6C3HED (intraperitoneal) in C3H/He mice [AID230, Type: other]
View
20
[SID87150]
NCI In Vivo Anticancer Drug Screen. Data for tumor model Lymphosarcoma Gardner 6C3HED (intraperitoneal) in C3AKF1 (CHKRF1) mice [AID232, Type: other]
View