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Cyclophosphamide (CID 2907) - Compound BioActivity Data
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BioActivity Outcomes:
Active(90)
 
 
Inactive(363)
 
 
Inconclusive(13)
 
 
Unspecified(2241)
 
 
Top Targets:
7TM GPCR Srx(21)
 
 
 
p450(18)
 
 
 
 
7TM GPCR Srsx(16)
 
 
 
NAD binding 8(6)
 
 
 
Pyr redox dim(5)
 
 
 
BioAssay Types:
Confirmatory(404)
 
 
 
 
 
Literature(359)
 
 
 
 
 
Screening(13)
 
 
Summary(1)
 
 
BioActivity Types:
Potency(189)
 
 
 
 
 
IC50(135)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 2653    Data Row: 2707   Total Pages: 136   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID90341534]
Potency 0.006qHTS Validation Assay for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails [AID488953, Type: confirmatory]chromobox protein homolog 1 [Homo sapiens] [gi:187960037]
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2
[SID103171472]
IC50 0.09Cytotoxicity against Homo sapiens (human) MDA-MB-231 cells after 48 hr by MTT assay [AID1085426, Type: confirmatory]
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3
[SID103171472]
IC50 0.15Cytotoxicity against Homo sapiens (human) K562 cells after 48 hr by MTT assay [AID1085429, Type: confirmatory]
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4
[SID103171472]
IC50 0.153Antiproliferative activity against Homo sapiens (human) K562 cells after 48 hr by MTT assay [AID1083866, Type: confirmatory]
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5
[SID103171472]
IC50 0.16Cytotoxicity against Homo sapiens (human) MCF7 cells after 48 hr by trypan blue assay [AID1095201, Type: confirmatory]
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6
[SID103171472]
IC50 0.24Cytotoxicity against Homo sapiens (human) HepG2 cells after 48 hr by MTT assay [AID1085427, Type: confirmatory]
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7
[SID103171472]
IC50 8.79Cytotoxicity against human HL60 cells by MTT assay [AID526308, Type: Literature]
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8
[SID90341534]
Potency 17.7828qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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9
[SID103171472]
IC50 37.6In vitro cytotoxicity against BALB/c 3T3 cells [AID41567, Type: Literature]
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10
[SID103171472]
LC50 37.6In vitro cytotoxicity in BALB/c3T3 mouse embryo fibroblasts. [AID41575, Type: Literature]
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11
[SID103171472]
LC50 37.6In vitro cytotoxicity was evaluated in mouse embryo BALB/c 3T3 cells [AID3372, Type: Literature]
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12
[SID87150]
NCI In Vivo Anticancer Drug Screen. Data for tumor model Lieberman Plasma Cell No. 1 (LPC-1) (intraperitoneal) in unknown mice [AID344, Type: other]
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13
[SID141705]
NCI In Vivo Anticancer Drug Screen. Data for tumor model L1210 Leukemia (intraperitoneal) in CD2F1 (CDF1) mice [AID256, Type: other]
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14
[SID141706]
NCI In Vivo Anticancer Drug Screen. Data for tumor model L1210 Leukemia (intraperitoneal) in CD2F1 (CDF1) mice [AID256, Type: other]
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15
[SID87150]
NCI In Vivo Anticancer Drug Screen. Data for tumor model Sarcoma M5076 (intraperitoneal) in B6C3F1 mice [AID292, Type: other]
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16
[SID87150]
NCI In Vivo Anticancer Drug Screen. Data for tumor model L1210 Leukemia resistant to Methyl-GAG; NSC 32946 (subcutaneous) in B6D2F1 (BDF1) mice [AID306, Type: other]
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17
[SID87150]
NCI In Vivo Anticancer Drug Screen. Data for tumor model L1210 Leukemia resistant to 6-MP and 6-Thioguanine; NSC 755, NSC 752 (intraperitoneal) in B6D2F1 (BDF1) mice [AID308, Type: other]
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18
[SID87150]
NCI In Vivo Anticancer Drug Screen. Data for tumor model Osteogenic Sarcoma HE 10734 (subcutaneous) in C3AKF1 (CHKRF1) mice [AID310, Type: other]
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19
[SID87150]
NCI In Vivo Anticancer Drug Screen. Data for tumor model C1498 Myeloid Leukemia (intraperitoneal) in B6D2F1 (BDF1) mice [AID312, Type: other]
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20
[SID87150]
NCI In Vivo Anticancer Drug Screen. Data for tumor model P388 Leukemia resistant to Adriamycin; NSC 123127, Developed at Scr 08 (intraperitoneal) in CD2F1 (CDF1) mice [AID322, Type: other]
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