Cyclopentolate (CID 2905) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(1)
 
 
Inactive(11)
 
 
Unspecified(14)
 
 
Top Targets:
Bcl-2 like(1)
 
 
DUF3371(1)
 
 
PTZ00435(1)
 
 
STKc AGC(1)
 
 
BioAssay Types:
Literature(14)
 
 
Screening(10)
 
 
Confirmatory(1)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 26    Data Row: 26   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID85209515]
 Ligands of bioamine (Class A) GPCRs [AID2062, Type: other]
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2
[SID131273740]
 Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholecystitis [AID625280, Type: Literature]
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3
[SID131273740]
 Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholelithiasis [AID625281, Type: Literature]
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4
[SID131273740]
 Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cirrhosis [AID625282, Type: Literature]
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5
[SID131273740]
 Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for elevated liver function tests [AID625283, Type: Literature]
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6
[SID131273740]
 Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatic failure [AID625284, Type: Literature]
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7
[SID131273740]
 Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatic necrosis [AID625285, Type: Literature]
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8
[SID131273740]
 Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatitis [AID625286, Type: Literature]
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9
[SID131273740]
 Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatomegaly [AID625287, Type: Literature]
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10
[SID131273740]
 Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for jaundice [AID625288, Type: Literature]
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11
[SID131273740]
 Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for liver disease [AID625289, Type: Literature]
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12
[SID131273740]
 Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for liver fatty [AID625290, Type: Literature]
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13
[SID131273740]
 Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for liver function tests abnormal [AID625291, Type: Literature]
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14
[SID131273740]
 Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) combined score [AID625292, Type: Literature]
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15
[SID131273740]
 Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for bilirubinemia [AID625279, Type: Literature]
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16
[SID85788899]
 Fluorescence Cell-Based Primary HTS to Identify Reactive Oxygen Species Inducers in Cancer Cells Measured in Cell-Based System Using Plate Reader and Imaging Combination - 2044-01_Activator_SinglePoint_HTS_Activity [AID624156, Type: screening]
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17
[SID49698850]
 High Throughput Screen to Identify Inhibitors of Mycobacterium tuberculosis H37Rv [AID1332, Type: confirmatory]
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18
[SID85788899]
 Luminescence Cell-Based Primary HTS to Identify Inhibitors of the Sonic Hedgehog Signaling Pathway [AID2313, Type: screening]
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19
[SID85788899]
 Luminescence Homogenous Primary HTS to Identify Inhibitors of STK33 Activity [AID2322, Type: screening]
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20
[SID85788899]
 Fluorescence Cell-Based Primary HTS to Measure Inhibition of Y box Binding Protein 1 Expression [AID434959, Type: screening]
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21
[SID85788899]
 Luminescence Cell-Based Primary HTS to Measure Viability of BJeLR cells [AID2275, Type: screening]
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22
[SID85788899]
 Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 [AID2241, Type: screening]Chain A, Human Bcl2-A1 In Complex With Bim-Bh3 Peptide [gi:167013344]
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23
[SID85788899]
 Development of IDH1/2 inhibitors (CTD2project) Measured in Biochemical System Using Plate Reader - 2107-01_Inhibitor_SinglePoint_HTS_Activity [AID624101, Type: screening]Isocitrate dehydrogenase 1 (NADP+), soluble [Homo sapiens] [gi:62203298]
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24
[SID85788899]
 Development of IDH1/2 inhibitors (CTD2project) Measured in Biochemical System Using Plate Reader - 2107-01_Inhibitor_SinglePoint_HTS_Activity [AID624101, Type: screening]Isocitrate dehydrogenase 1 (NADP+), soluble [Homo sapiens] [gi:62203298]
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25
[SID85788899]
 Development of IDH1/2 inhibitors (CTD2project) Measured in Biochemical System Using Plate Reader - 2107-01_Inhibitor_SinglePoint_HTS_Activity [AID624101, Type: screening]Isocitrate dehydrogenase 1 (NADP+), soluble [Homo sapiens] [gi:62203298]
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26
[SID85788899]
 Luminescence Cell-Based Primary HTS to Identify Inhibitors of MITF [AID2240, Type: screening]microphthalmia-associated transcription factor isoform 1 [Homo sapiens] [gi:38156699]
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27
[SID85788899]
 Luminescence Cell-Based Primary HTS to Identify Inhibitors of MITF [AID2240, Type: screening]microphthalmia-associated transcription factor isoform 1 [Homo sapiens] [gi:38156699]
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28
[SID85788899]
 Luminescence Cell-Based Primary HTS to Identify Inhibitors of STK33 [AID2330, Type: screening]serine/threonine kinase 33 [Homo sapiens] [gi:12830367]
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29
[SID85788899]
 Luminescence Cell-Based Primary HTS to Identify Inhibitors of STK33 [AID2330, Type: screening]serine/threonine kinase 33 [Homo sapiens] [gi:12830367]
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30
[SID85788899]
 Luminescence Cell-Based Primary HTS to Identify Inhibitors of STK33 [AID2330, Type: screening]serine/threonine kinase 33 [Homo sapiens] [gi:12830367]
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31
[SID49698850]
 Vibrio cholerae assay for pro-quorum sensing small molecules [AID686977, Type: screening]cyclic AMP receptor protein [Vibrio cholerae O1 biovar El Tor str. N16961] [gi:9657203]
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