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N-hydroxy-2-(naphthalen-1-yl)acetamide (CID 289794) - Compound BioActivity Data
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BioActivity Outcomes:
Active(7)
 
 
Inactive(26)
 
 
Unspecified(1)
 
 
Top Targets:
PLAT LOX(2)
 
 
Pyr redox dim(2)
 
 
PLDc mTdp1 2(2)
 
 
ANK(2)
 
 
Peptidase M17(2)
 
 
BioAssay Types:
Confirmatory(22)
 
 
 
 
Literature(3)
 
 
Screening(2)
 
 
BioActivity Types:
Potency(17)
 
 
 
IC50(7)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 33    Data Row: 34   Total Pages: 2   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID104233678]
Average HUM17LAP IC50 0.99Counterscreen for inhibitors of PFM17LAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Human M17LAP (HUM17LAP) [AID602214, Type: confirmatory]leucine aminopeptidase [Homo sapiens] [gi:4335941]
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2
[SID104233678]
Average PFM17LAP IC50 6.11QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) [AID588688, Type: confirmatory]M17 leucyl aminopeptidase [Plasmodium falciparum 3D7] [gi:23497510]
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3
[SID103402735]
IC50 26.9154Logarithmic value of inhibitory concentration against 5-lipoxygenase in rat basophilic leukemia cells (RBL-1) [AID7185, Type: Literature]Arachidonate 5-lipoxygenase [gi:729945]
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4
[SID103402735]
IC50 27In vitro inhibitory activity against RBL-1 5-LO [AID6809, Type: Literature]
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5
[SID103402735]
IC50 27In vitro inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cells(RBL-1) [AID7184, Type: Literature]Arachidonate 5-lipoxygenase [gi:729945]
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6
[SID104233678]
Average CC50 50Vero Cytoxicity Assay: A Cell Based Secondary Assay To Explore Cytotoxicity of Compounds that Inhibit Plasmodium falciparum M1 Aspartyl Aminopeptidase (PFM17LAP) [AID588707, Type: confirmatory]
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7
[SID104233678]
Average PFM1AAP IC50 79.39Counterscreen for inhibitors of PFM17LAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M1AAP (PFM1AAP) [AID588698, Type: confirmatory]m1-family aminopeptidase [Plasmodium falciparum 3D7] [gi:23615263]
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8
[SID124897793]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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9
[SID124897793]
Potency qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primary qHTS [AID720579, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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10
[SID124897793]
Potency qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: Venus Reporter Primary qHTS [AID720580, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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11
[SID124897793]
Potency qHTS of alpha-syn Inhibitors [AID652106, Type: confirmatory]Alpha-synuclein [gi:586067]
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12
[SID124897793]
Potency qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression [AID624202, Type: confirmatory]BRCA1 [Homo sapiens] [gi:1698399]
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13
[SID124897793]
Potency qHTS Assay for Activators of ClpP [AID651965, Type: confirmatory]ClpP [Bacillus subtilis] [gi:2668494]
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14
[SID124897793]
Potency A Quantitative High throughput Screen to Identify Chemical Modulators of PINK1 Expression [AID624263, Type: confirmatory]Parkin [Homo sapiens] [gi:3063388]
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15
[SID124897793]
Potency qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line [AID686971, Type: confirmatory]
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16
[SID104233678]
Late stage assay provider results from the probe development effort to identify inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (M17LAP): radiolabel-based cell-based assay to identify compounds that inhibit P. falciparum growth in RBCs Set 2 [AID743274, Type: screening]
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17
[SID432463]
NCI Yeast Anticancer Drug Screen. Data for the rad50 strain [AID155, Type: other]
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18
[SID432463]
NCI Yeast Anticancer Drug Screen. Data for the mec2-1 strain [AID157, Type: other]
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19
[SID432463]
NCI Yeast Anticancer Drug Screen. Data for the sgs1 mgt1 strain [AID161, Type: other]
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20
[SID432463]
NCI Yeast Anticancer Drug Screen. Data for the cln2 rad14 strain [AID165, Type: other]
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