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catechol (CID 289) - Compound BioActivity Data
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BioActivity Outcomes:
Active(215)
 
 
Inactive(766)
 
 
Inconclusive(230)
 
 
Unspecified(495)
 
 
Top Targets:
7TM GPCR Srx(42)
 
 
 
7TM GPCR Srsx(29)
 
 
 
NR LBD PPAR(21)
 
 
 
NR LBD ER(19)
 
 
 
 
 
NR LBD AR(17)
 
 
 
 
BioAssay Types:
Confirmatory(696)
 
 
 
 
 
Screening(324)
 
 
 
Literature(118)
 
 
 
 
Summary(49)
 
 
 
 
BioActivity Types:
Potency(544)
 
 
 
 
 
IC50(140)
 
 
 
 
Ki(35)
 
 
 
Kd(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1328    Data Row: 1706   Total Pages: 86   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID170482493]
Kd 0.0004Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Crystal Structure Of Siderocalin (Ngal, Lipocalin 2) Complexed With Ferric Catechol [gi:295789296]
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2
[SID170482493]
Kd 0.0004Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Crystal Structure Of Siderocalin (Ngal, Lipocalin 2) Complexed With Ferric Catechol [gi:295789296]
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3
[SID103196138]
IC50 0.01Compound was evaluated for hydroxyl radical (OH) scavenging activity [AID226669, Type: confirmatory]
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4
[SID103196138]
IC50 0.868DRUGMATRIX: Lipoxygenase 15-LO enzyme inhibition (substrate: Linoleic acid) [AID625146, Type: confirmatory]Arachidonate 15-lipoxygenase [gi:126397]
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5
[SID57264281]
Potency 1.2589qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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6
[SID50105556]
Potency 1.5849qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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7
[SID11111004]
Potency 1.5849qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II) [AID886, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921310]
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8
[SID11111004]
Potency 1.5849qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II) [AID886, Type: confirmatory]Chain B, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921311]
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9
[SID90341698]
Potency 1.7783qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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10
[SID90341698]
Potency 1.9953qHTS for Inhibitors of Glutaminase (GLS): LOPAC Validation [AID624146, Type: confirmatory]GLS protein [Homo sapiens] [gi:71051501]
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11
[SID17389988]
Potency 2.5119qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II) [AID886, Type: confirmatory]Chain B, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921311]
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12
[SID17389988]
Potency 2.5119qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II) [AID886, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921310]
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13
[SID50105556]
Potency 2.5119qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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14
[SID103196138]
Ki 3.48Inhibition of bovine carbonic anhydrase 3 using 4-nitrophenylacetate as substrate after 3 mins using spectrophotometry by Lineweaver-Burk plot analysis [AID644088, Type: Literature]Carbonic anhydrase 3 [gi:118572923]
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15
[SID103196138]
Ki 4.2Inhibition of human carbonic anhydrase 5B by stopped-flow CO2 hydration assay [AID342480, Type: Literature]Carbonic anhydrase 5B, mitochondrial [gi:8928041]
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16
[SID103196138]
Ki 4.2Inhibition of human CA5B by stopped-flow CO2 hydration assay [AID462275, Type: Literature]Carbonic anhydrase 5B, mitochondrial [gi:8928041]
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17
[SID17389988]
Potency 5.0119qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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18
[SID17389988]
Potency 5.9557qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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19
[SID90341698]
Potency 5.9728qHTS Validation Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1) [AID488816, Type: confirmatory]flap endonuclease 1 [Homo sapiens] [gi:4758356]
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20
[SID90341698]
Potency 5.9728qHTS Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1). [AID588795, Type: confirmatory]flap endonuclease 1 [Homo sapiens] [gi:4758356]
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