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BioActivity Data for Compound 4-cresol (CID 2879)

BioActivity Outcomes:
Active(6)
 
 
Inactive(691)
 
 
Inconclusive(51)
 
 
Unspecified(41)
 
 
Top Targets:
NR LBD PPAR(39)
 
 
NR LBD ER(37)
 
 
 
 
NR LBD AR(37)
 
 
 
NR LBD GR(22)
 
 
 
NR LBD TR(21)
 
 
 
BioAssay Types:
Confirmatory(554)
 
 
 
 
Summary(123)
 
 
 
Literature(36)
 
 
 
 
Screening(15)
 
 
 
BioAssay Categories:
In vitro(5)
 
 
 
In vivo(2)
 
 
Biochemical(8)
 
 
 
 
Toxicity(74)
 
 
 
 
 
ADME(14)
 
 
Cell-based(21)
 
 
 
 
Organism-base..(2)
 
 
BioActivity Types:
Potency(601)
 
 
 
 
IC50(11)
 
 
 
 
AC50(6)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 390    Data Row: 789   Total Pages: 40   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103179460]
IC50 0.00182Inhibition of acetylcholinesterase. [AID32248, Type: Literature]
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2
[SID103179460]
IC50 4.9IC50 against acetylcholinesterase; value ranges from 1-4900 nM. [AID32280, Type: Literature]
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3
[SID103179460]
Km 10Apparent Michaelis constant (Km) against Arylsulfotransferase (AST IV) [AID39219, Type: Literature]
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4
[SID144206791]
Potency-Replicate_1 26.6032qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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5
[SID48415061]
DSSTox (EPAFHM) EPA Fathead Minnow Acute Toxicity [AID1188, Type: other]
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6
[SID48421963]
DSSTox (NCTRER) National Center for Toxicological Research Estrogen Receptor Binding Database [AID1204, Type: screening]
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7
[SID103179460]
IC50 290Tested for inhibition of ferrous salt/ascorbate induced lipidic peroxidation of membrane lipid of rat hepatocytes [AID248526, Type: Literature]
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8
[SID103179460]
IC50 290Antioxidant activity assessed as inhibition of TBARS production in ferrous salt/ascorbate-induced lipid peroxidation in Wistar rat liver microsomal membrane [AID264513, Type: Literature]
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9
[SID103179460]
IC50 3640Inhibitory activity on germination of Bacillus subtilis PCI219 spores was determined. [AID40623, Type: Literature]
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10
[SID103179460]
Partition coefficient (logD7.2) [AID26261, Type: Literature]
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11
[SID103179460]
Binding constant against bovine serum albumin [AID203473, Type: Literature]
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12
[SID103179460]
Ratio of kcat/Km determined for catalytic efficiency in sulfonation against AST IV [AID229377, Type: Literature]
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13
[SID103179460]
Lipophilicity determined as logarithm of the partition coefficient in the alkane/water system [AID237685, Type: Literature]
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14
[SID103179460]
Calculated partition coefficient (clogP) [AID19211, Type: Literature]
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15
[SID103179460]
Aqueous solubility [AID19262, Type: Literature]
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16
[SID103179460]
Cytotoxicity against human HL60 cells [AID282836, Type: Literature]
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17
[SID103179460]
Cytotoxicity against human CCRF-CEM cells [AID282838, Type: Literature]
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18
[SID103179460]
Lipophilicity, log P of the compound [AID385221, Type: Literature]
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19
[SID103179460]
Capacity ratio (log k'w) [AID23978, Type: Literature]
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20
[SID103179460]
Dissociation constant (pKa) [AID25611, Type: Literature]
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