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4-cresol (CID 2879) - Compound BioActivity Data
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BioActivity Outcomes:
Active(6)
 
 
Inactive(631)
 
 
Inconclusive(49)
 
 
Unspecified(39)
 
 
Top Targets:
NR LBD PPAR(39)
 
 
NR LBD ER(37)
 
 
 
 
NR LBD AR(37)
 
 
 
NR LBD GR(22)
 
 
 
NR LBD TR(21)
 
 
 
BioAssay Types:
Confirmatory(510)
 
 
 
 
Summary(111)
 
 
 
Literature(34)
 
 
 
 
Screening(9)
 
 
 
BioActivity Types:
Potency(556)
 
 
 
 
IC50(6)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 359    Data Row: 725   Total Pages: 37   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103179460]
IC50 0.00182Inhibition of acetylcholinesterase. [AID32248, Type: Literature]
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2
[SID103179460]
IC50 4.9IC50 against acetylcholinesterase; value ranges from 1-4900 nM. [AID32280, Type: Literature]
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3
[SID103179460]
Km 10Apparent Michaelis constant (Km) against Arylsulfotransferase (AST IV) [AID39219, Type: Literature]
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4
[SID144206791]
Potency-Replicate_1 26.6032qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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5
[SID48415061]
DSSTox (EPAFHM) EPA Fathead Minnow Acute Toxicity [AID1188, Type: other]
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6
[SID48421963]
DSSTox (NCTRER) National Center for Toxicological Research Estrogen Receptor Binding Database [AID1204, Type: screening]
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7
[SID103179460]
IC50 290Tested for inhibition of ferrous salt/ascorbate induced lipidic peroxidation of membrane lipid of rat hepatocytes [AID248526, Type: Literature]
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8
[SID103179460]
IC50 290Antioxidant activity assessed as inhibition of TBARS production in ferrous salt/ascorbate-induced lipid peroxidation in Wistar rat liver microsomal membrane [AID264513, Type: Literature]
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9
[SID103179460]
IC50 3640Inhibitory activity on germination of Bacillus subtilis PCI219 spores was determined. [AID40623, Type: Literature]
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10
[SID103179460]
Inhibition of Bacillus subtilis PCI219 spore germination, expressed as log 1/I50 [AID40936, Type: Literature]
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11
[SID103179460]
Binding constant against bovine serum albumin [AID203473, Type: Literature]
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12
[SID103179460]
Ratio of kcat/Km determined for catalytic efficiency in sulfonation against AST IV [AID229377, Type: Literature]
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13
[SID103179460]
Lipophilicity determined as logarithm of the partition coefficient in the alkane/water system [AID237685, Type: Literature]
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14
[SID103179460]
Maximal velocity (Vmax) against Arylsulfotransferase (AST IV) [AID39220, Type: Literature]
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15
[SID8149273]
Screen for compounds that increase glutamate transport activity in MN-1 cell line (GluUPTAKE) [AID1612, Type: other]
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16
[SID8149273]
Screen for compounds that inhibit protein aggregation formed by mutant SOD1 (GFPSOD1) [AID1613, Type: other]
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17
[SID8149273]
Screen for compounds that reduce polyglutamine (polyQ) inclusions in nerve growth factor (NGF)-treated PC12 cells (GFPQ80) [AID1614, Type: other]
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18
[SID8149273]
Yeast cell-based screen for compounds that suppress polyglutamine aggregation in vivo (75Q-TubH) [AID1616, Type: other]
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19
[SID103179460]
Calculated partition coefficient (clogP) [AID19211, Type: Literature]
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20
[SID103179460]
Aqueous solubility [AID19262, Type: Literature]
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