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Coumaphos (CID 2871) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(47)
 
 
Inactive(537)
 
 
Inconclusive(131)
 
 
Unspecified(6)
 
 
Top Targets:
NR LBD PPAR(29)
 
 
 
NR LBD AR(23)
 
 
 
 
NR LBD ER(23)
 
 
 
NR LBD VDR(16)
 
 
 
NR LBD GR(14)
 
 
 
BioAssay Types:
Confirmatory(372)
 
 
 
 
 
Screening(178)
 
 
 
Literature(80)
 
 
 
 
 
Summary(72)
 
 
 
 
BioActivity Types:
Potency(422)
 
 
 
 
 
Ki(12)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 445    Data Row: 721   Total Pages: 15   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144211086]
AhR Potency (uM) 0.0432771qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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2
[SID144209039]
AhR Potency (uM) 0.0654778qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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3
[SID144209039]
Potency-Replicate_1 0.098qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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4
[SID144204842]
AhR Potency (uM) 0.438128qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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5
[SID144204842]
Potency-Replicate_1 0.5956qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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6
[SID50107237]
Potency 1.7783qHTS assay for small molecule activators of the rat pregnane X receptor (rPXR) signaling pathway [AID651751, Type: confirmatory]pregnane X receptor [Rattus norvegicus] [gi:5702233]
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7
[SID50107237]
Potency-Replicate_1 1.7783qHTS assay for small molecule activators of the human pregnane X receptor (PXR) signaling pathway [AID720659, Type: confirmatory]pregnane X nuclear receptor [Homo sapiens] [gi:325495557]
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8
[SID26747703]
Potency 1.9953qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
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9
[SID103558152]
Ki 2.23Inhibition of human recombinant carbonic anhydrase 6 preincubated for 15 mins to 72 hrs measured after 6 hrs by stopped flow CO2 hydration method [AID649885, Type: Literature]Carbonic anhydrase 6 [gi:116241278]
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10
[SID103558152]
Ki 3.41Inhibition of human recombinant carbonic anhydrase 5B preincubated for 15 mins to 72 hrs measured after 6 hrs by stopped flow CO2 hydration method [AID649886, Type: Literature]Carbonic anhydrase 5B, mitochondrial [gi:8928041]
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11
[SID103558152]
Ki 4.14Inhibition of human recombinant carbonic anhydrase 14 preincubated for 15 mins to 72 hrs measured after 6 hrs by stopped flow CO2 hydration method [AID649880, Type: Literature]Carbonic anhydrase 14 [gi:8928036]
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12
[SID103558152]
Ki 4.23Inhibition of human recombinant carbonic anhydrase 13 preincubated for 15 mins to 72 hrs measured after 6 hrs by stopped flow CO2 hydration method [AID649881, Type: Literature]Carbonic anhydrase 13 [gi:30580350]
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13
[SID103558152]
Ki 4.62Inhibition of human recombinant carbonic anhydrase 3 preincubated for 15 mins to 72 hrs measured after 6 hrs by stopped flow CO2 hydration method [AID649889, Type: Literature]Carbonic anhydrase 3 [gi:134047703]
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14
[SID103558152]
Ki 4.68Inhibition of human recombinant carbonic anhydrase 7 preincubated for 15 mins to 72 hrs measured after 6 hrs by stopped flow CO2 hydration method [AID649884, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
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15
[SID103558152]
Ki 5.09Inhibition of human recombinant carbonic anhydrase 5A preincubated for 15 mins to 72 hrs measured after 6 hrs by stopped flow CO2 hydration method [AID649887, Type: Literature]Carbonic anhydrase 5A, mitochondrial [gi:461680]
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16
[SID103558152]
Ki 5.48Inhibition of human recombinant carbonic anhydrase 4 preincubated for 15 mins to 72 hrs measured after 6 hrs by stopped flow CO2 hydration method [AID649888, Type: Literature]Carbonic anhydrase 4 [gi:115465]
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17
[SID103558152]
Ki 6.41Inhibition of human recombinant carbonic anhydrase 9 preincubated for 15 mins to 72 hrs measured after 6 hrs by stopped flow CO2 hydration method [AID649883, Type: Literature]Carbonic anhydrase 9 [gi:83300925]
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18
[SID89854493]
Potency 6.5131qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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19
[SID26747703]
Potency 8.0875S16 Schwann cell PMP22 intronic element firefly luciferase assay [AID624032, Type: confirmatory]peripheral myelin protein 22 [Rattus norvegicus] [gi:8393992]
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20
[SID103558152]
Ki 9.52Inhibition of human recombinant carbonic anhydrase 12 preincubated for 15 mins to 72 hrs measured after 6 hrs by stopped flow CO2 hydration method [AID649882, Type: Literature]Carbonic anhydrase 12 [gi:5915866]
View
21
[SID144211086]
Potency-Replicate_1 17.2289qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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22
[SID144211086]
Potency-Replicate_1 17.2289qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
View
23
[SID144211086]
Potency-Replicate_1 19.3312qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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24
[SID144209039]
Potency-Replicate_1 19.5476qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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25
[SID144209039]
Potency-Replicate_1 19.5476qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
View
26
[SID144209039]
Potency-Replicate_1 19.5476qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
View
27
[SID144211086]
Potency-Replicate_1 24.3365qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
View
28
[SID144209039]
Potency-Replicate_1 39.3382qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway [AID743035, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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29
[SID144209039]
Ratio Potency (uM) 39.3382qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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30
[SID144211086]
Ratio Potency (uM) 46.2271qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
View
31
[SID144211086]
Potency-Replicate_1 48.9662qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway [AID743035, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
View
32
[SID144211086]
Potency-Replicate_1 61.1306qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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33
[SID144211086]
Potency-Replicate_1 61.1306qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
View
34
[SID144209039]
Potency-Replicate_1 61.815qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
View
35
[SID144209039]
Potency-Replicate_1 69.3576qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
View
36
[SID50107237]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_1, Type: other]
View
37
[SID50107237]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_2, Type: other]
View
38
[SID50107237]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_3, Type: other]
View
39
[SID50107237]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_4, Type: other]
View
40
[SID50107237]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_7, Type: other]
View
41
[SID26747703]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_3, Type: Literature]
View
42
[SID26747703]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_13, Type: Literature]
View
43
[SID89854493]
TRFRET-based cell-based primary high throughput screening assay to identify inhibitors of cell surface Prion Protein (PRPC) [AID720596, Type: screening]major prion protein preproprotein [Homo sapiens] [gi:4506113]
View
44
[SID26747703]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_17, Type: Literature]
View
45
[SID26747703]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_7, Type: Literature]
View
46
[SID89854493]
TRFRET-based cell-based high throughput confirmation assay to identify inhibitors of cell surface Prion Protein (PRPC) [AID743200, Type: screening]major prion protein preproprotein [Homo sapiens] [gi:4506113]
View
47
[SID144211086]
qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway: Summary [AID743240, Type: summary]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
View
48
[SID103558152]
Ki 61.7Inhibition of human recombinant carbonic anhydrase 1 preincubated for 15 mins to 72 hrs measured after 6 hrs by stopped flow CO2 hydration method [AID649891, Type: Literature]Carbonic anhydrase 1 [gi:115449]
View
49
[SID103558152]
Ki 200Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins to 72 hrs measured after 6 hrs by stopped flow CO2 hydration method [AID649890, Type: Literature]Carbonic anhydrase 2 [gi:115456]
View
50
[SID89854493]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View