Bookmark and Share
GNF-Pf-5576 (CID 2852165) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(14)
 
 
Inactive(663)
 
 
Inconclusive(13)
 
 
Unspecified(2)
 
 
Top Targets:
7TM GPCR Srx(23)
 
 
 
7TM GPCR Srsx(22)
 
 
 
 
Bcl-2 like(11)
 
 
alkPPc(10)
 
 
G-alpha(8)
 
 
 
BioAssay Types:
Screening(462)
 
 
 
 
Confirmatory(200)
 
 
 
 
 
Literature(15)
 
 
 
 
BioActivity Types:
Potency(147)
 
 
 
 
 
IC50(39)
 
 
EC50(10)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 628    Data Row: 692   Total Pages: 35   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103712786]
EC50 0.01454NOVARTIS: Inhibition of Plasmodium falciparum W2 (drug-resistant) proliferation in erythrocyte-based infection assay [AID449704, Type: Literature]
View
2
[SID24807345]
Potency 0.0206qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor: Hit Validation with GloSensor [AID588790, Type: confirmatory]beta-2 adrenergic receptor [Homo sapiens] [gi:4501969]
View
3
[SID103712786]
EC50 0.2046NOVARTIS: Inhibition of Plasmodium falciparum 3D7 (drug-susceptible) proliferation in erythrocyte-based infection assay [AID449703, Type: Literature]
View
4
[SID24807345]
Potency 0.2332Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
View
5
[SID24807345]
Potency 15.8489qHTS of PTHR Inhibitors: Primary Screen [AID743266, Type: confirmatory]parathyroid hormone/parathyroid hormone-related peptide receptor precursor [Homo sapiens] [gi:296080761]
View
6
[SID103712786]
CC50 42.54NOVARTIS: Cytotoxicity against human hepatocellular carcinoma cell line (Huh7) [AID449705, Type: Literature]
View
7
[SID24807345]
Leishmania major promastigote HTS [AID1063, Type: screening]
View
8
[SID24807345]
Aqueous Solubility from MLSMR Stock Solutions [AID1996, Type: other]
View
9
[SID24807345]
Primary cell-based high-throughput screening assay for potentiators or agonists of NPY-Y1 [AID1304, Type: screening]neuropeptide Y receptor type 1 [Homo sapiens] [gi:4505445]
View
10
[SID24807345]
Primary cell-based high-throughput screening assay for potentiators or agonists of NPY-Y2 [AID1359, Type: screening]neuropeptide Y receptor type 2 [Homo sapiens] [gi:4505447]
View
11
[SID24807345]
HTS Assay for Allosteric Agonists of the Human D2 Dopamine Receptor: Primary Screen for Agonists [AID485358, Type: screening]D(2) dopamine receptor isoform long [Homo sapiens] [gi:4503385]
View
12
[SID24807345]
HTS Assay for Allosteric Antagonists of the Human D2 Dopamine Receptor: Primary Screen for Antagonists [AID485344, Type: screening]D(2) dopamine receptor isoform long [Homo sapiens] [gi:4503385]
View
13
[SID24807345]
Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the Galanin Receptor 3 (GalR3) [AID651719, Type: screening]galanin receptor type 3 [Homo sapiens] [gi:4503907]
View
14
[SID24807345]
Fluorescence-based cell-based primary high throughput confirmation assay to identify antagonists of the Galanin Receptor 3 (GalR3) [AID652245, Type: screening]galanin receptor type 3 [Homo sapiens] [gi:4503907]
View
15
[SID103712786]
NOVARTIS: Inhibition Frequency Index (IFI) - the number of HTS assays where a compound showed > 50% inhibition/induction, expressed as a percentage of the number of assays in which the compound was tested. [AID449706, Type: Literature]
View
16
[SID24807345]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
17
[SID24807345]
Potency 39.8107qHTS for Inhibitors of ATXN expression [AID651635, Type: confirmatory]ataxin-2 [Homo sapiens] [gi:171543895]
View
18
[SID24807345]
Potency 89.1251qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
View
19
[SID24807345]
uHTS Fluorescent assay for identification of inhibitors of Apaf-1 [AID489030, Type: screening]Apoptotic peptidase activating factor 1 [Homo sapiens] [gi:187952397]
View
20
[SID24807345]
uHTS Fluorescent assay for identification of activators of Apaf-1 [AID489031, Type: screening]Apoptotic peptidase activating factor 1 [Homo sapiens] [gi:187952397]
View