Bookmark and Share
Danazol (CID 28417) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(85)
 
 
Inactive(662)
 
 
Inconclusive(106)
 
 
Unspecified(1329)
 
 
Top Targets:
7TM GPCR Srx(30)
 
 
 
 
7TM GPCR Srsx(28)
 
 
 
 
NR LBD PPAR(21)
 
 
 
NR LBD AR(18)
 
 
 
 
p450(18)
 
 
 
 
 
BioAssay Types:
Confirmatory(395)
 
 
 
 
 
Screening(365)
 
 
 
 
Literature(160)
 
 
 
 
 
Summary(48)
 
 
 
 
BioActivity Types:
Potency(295)
 
 
 
 
 
IC50(153)
 
 
 
 
 
Kd(1)
 
 
EC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1966    Data Row: 2182   Total Pages: 110   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103543149]
Kd 0.00631Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin [AID318680, Type: Literature]Sex hormone-binding globulin [gi:134907]
View
2
[SID144212257]
Potency-Replicate_1 0.0097qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743040, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
View
3
[SID103543149]
IC50 0.012DRUGMATRIX: Androgen (Testosterone) AR radioligand binding (ligand: [3H] Mibolerone) [AID625228, Type: confirmatory]Androgen receptor [gi:113832]
View
4
[SID144212257]
Ratio Potency (uM) 0.0160903qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway: Summary [AID743053, Type: summary]AR protein [Homo sapiens] [gi:124375976]
View
5
[SID144212257]
Potency-Replicate_1 0.0347qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway [AID743036, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
View
6
[SID144205667]
Potency-Replicate_1 0.075qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743040, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
View
7
[SID144205667]
Ratio Potency (uM) 0.221476qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
View
8
[SID103543149]
IC50 0.259DRUGMATRIX: Progesterone radioligand binding (ligand: [3H] R-5020) [AID625172, Type: confirmatory]Progesterone receptor [gi:75071465]
View
9
[SID103543149]
IC50 0.3DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) [AID625248, Type: confirmatory]Cytochrome P450 2C9 [gi:6686268]
View
10
[SID144205667]
Potency-Replicate_1 0.6682qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
11
[SID144212257]
Potency-Replicate_1 0.9689qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
12
[SID144205667]
Ratio Potency (uM) 1.028qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway: Summary [AID743053, Type: summary]AR protein [Homo sapiens] [gi:124375976]
View
13
[SID103543149]
IC50 2.535DRUGMATRIX: Phosphodiesterase PDE3 enzyme inhibition (substrate: [3H]cAMP + cAMP) [AID625165, Type: confirmatory]
View
14
[SID103543149]
IC50 2.978DRUGMATRIX: Sodium Channel, Site 2 radioligand binding (ligand: [3H] Batrachotoxin) [AID625225, Type: confirmatory]
View
15
[SID26757819]
Potency 3.1623qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
16
[SID144205667]
Potency-Replicate_1 3.378qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
17
[SID103543149]
IC50 4.314DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone) [AID625263, Type: confirmatory]Glucocorticoid receptor [gi:121069]
View
18
[SID144205667]
Potency-Replicate_1 5.3538qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway [AID720692, Type: confirmatory]glucocorticoid receptor [Homo sapiens] [gi:311348376]
View
19
[SID103543149]
IC50 5.698DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55) [AID625207, Type: confirmatory]Sodium-dependent noradrenaline transporter [gi:128616]
View
20
[SID144205667]
Ratio Potency (uM) 5.77522qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View