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sodium bisulfide (CID 28015) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(13)
 
 
Inactive(8)
 
 
Unspecified(16)
 
 
Top Targets:
alpha CA I II..(11)
 
 
BioAssay Types:
Literature(29)
 
 
 
BioActivity Types:
Ki(26)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 37    Data Row: 37   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID124969973]
Ki 0.6Inhibition of human carbonic anhydrase 1 after 15 mins by CO2 hydrase assay at pH 7.5 [AID587130, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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2
[SID124969973]
Ki 0.6Inhibition of recombinant human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay at pH 8.3 [AID598726, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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3
[SID124969973]
Ki 0.6Inhibition of human cytosolic carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assay [AID714401, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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4
[SID124969973]
Ki 0.6Inhibition of human recombinant wild type CA1 by stopped-flow CO2 hydration method [AID724722, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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5
[SID124969973]
Ki 0.6Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assay [AID730754, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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6
[SID124969973]
Ki 40Inhibition of human carbonic anhydrase 2 after 15 mins by CO2 hydrase assay at pH 7.5 [AID587131, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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7
[SID124969973]
Ki 40Inhibition of recombinant human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay at pH 8.3 [AID598728, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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8
[SID124969973]
Ki 40Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay [AID714400, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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9
[SID124969973]
Ki 40Inhibition of human recombinant wild type CA2 by stopped-flow CO2 hydration method [AID724721, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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10
[SID124969973]
Ki 40Inhibition of human cytosolic carbonic anhydrase-2 preincubated for 15 mins by stopped flow CO2 hydration assay [AID730373, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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11
[SID124969973]
Ki 40Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay [AID730753, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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12
[SID124969973]
Induction of H2S production measured every 15 sec to 1 min by thiobimane fluorescent method [AID695527, Type: Literature]
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13
[SID124969973]
Vasodilatory activity in CD1 mouse endothelium-denuded aortic ring assessed as reversal of L-phenylehrine-induced contraction [AID695533, Type: Literature]
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14
[SID124969973]
Ki 74Inhibition of Vibrio cholerae alpha carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration assay [AID730751, Type: Literature]
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15
[SID124969973]
Ki 82Inhibition of human recombinant CA10 mutant after 15 mins by stopped-flow CO2 hydration method [AID724719, Type: Literature]
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16
[SID124969973]
Ki 88Inhibition of human recombinant CA11 mutant after 15 mins by stopped-flow CO2 hydration method [AID724718, Type: Literature]
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17
[SID124969973]
Ki 350Inhibition of Streptococcus pneumoniae beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assay [AID552785, Type: Literature]
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18
[SID124969973]
Ki 380Inhibition of Sulfurihydrogenibium azorense alpha-carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration assay [AID714403, Type: Literature]
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19
[SID124969973]
Ki 390Inhibition of Salmonella Typhimurium carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay at pH 8.3 [AID598732, Type: Literature]
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20
[SID124969973]
Ki 490Inhibition of Astrosclera willeyana recombinant GST-tagged astrosclerin 3 expressed in Escherichia coli BL21-DE3-RIPL cells preincubated for 15 mins measured for 10 to 100 secs by stopped flow CO2 hydration assay [AID647373, Type: Literature]
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21
[SID124969973]
Ki 580Inhibition of Sulfurihydrogenibium yellowstonense YO3AOP1 alpha-carbonic anhydrase-catalyzed CO2 hydration reaction preincubated for 15 mins by stopped flow CO2 hydrase assay [AID677270, Type: Literature]
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22
[SID124969973]
Ki 580Inhibition of Helicobacter pylori beta-carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration assay [AID730368, Type: Literature]
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23
[SID124969973]
Ki 620Inhibition of human recombinant CA8 mutant after 15 mins by stopped-flow CO2 hydration method [AID724720, Type: Literature]
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24
[SID124969973]
Ki 690Inhibition of Helicobacter pylori alpha carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration assay [AID730752, Type: Literature]
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25
[SID124969973]
Ki 690Inhibition of Helicobacter pylori alpha-carbonic anhydrase-catalyzed CO2 hydration reaction preincubated for 15 mins by stopped flow CO2 hydrase assay [AID677271, Type: Literature]
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26
[SID124969973]
Ki 820Inhibition of Salmonella Typhimurium carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay at pH 8.3 [AID598731, Type: Literature]
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27
[SID124969973]
Ki 860Inhibition of Flaveria bidentis beta-carbonic anhydrase-1 preincubated for 15 mins by stopped flow CO2 hydration assay [AID730372, Type: Literature]
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28
[SID124969973]
Ki 1000Inhibition of Leptonychotes weddellii alpha-carbonic anhydrase after 15 mins by CO2 hydrase assay at pH 7.5 [AID587132, Type: Literature]
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29
[SID124969973]
Vasodilatory activity in Wistar rat RASMC cells assessed as increase in cGMP levels at 50 uM after 5 mins by enzyme immunoassay relative to control [AID695531, Type: Literature]
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30
[SID435560]
NCI In Vivo Anticancer Drug Screen. Data for tumor model L1210 Leukemia (intraperitoneal) in B6D2F1 (BDF1) mice [AID248, Type: other]
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31
[SID435560]
NCI In Vivo Anticancer Drug Screen. Data for tumor model P388 Leukemia (intraperitoneal) in B6D2F1 (BDF1) mice [AID328, Type: other]
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32
[SID435560]
NCI Yeast Anticancer Drug Screen. Data for the rad50 strain [AID155, Type: other]
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33
[SID435560]
NCI Yeast Anticancer Drug Screen. Data for the mec2-1 strain [AID157, Type: other]
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34
[SID435560]
NCI Yeast Anticancer Drug Screen. Data for the sgs1 mgt1 strain [AID161, Type: other]
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35
[SID435560]
NCI Yeast Anticancer Drug Screen. Data for the cln2 rad14 strain [AID165, Type: other]
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36
[SID435560]
NCI Yeast Anticancer Drug Screen. Data for the bub3 strain [AID167, Type: other]
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37
[SID435560]
NCI Yeast Anticancer Drug Screen. Data for the mlh1 rad18 strain [AID175, Type: other]
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