| 1 | [SID103227081] | Active | Ki | 0.00037 | Binding affinity against human vasopressin V1b receptor was determined by using plasma membranes from CHO cells stably transfected with VP/OT receptors [AID217360, Type: Literature] | |   View X | Row No. | 1 | | Structure | 
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Active | | Ki | 0.00037 [uM] | | BioAssay | Binding affinity against human vasopressin V1b receptor was determined by using plasma membranes from CHO cells stably transfected with VP/OT receptors | | AID | 217360 | | BioAssay type | Literature | | Target | | | PubMed | 15084136 | | Data Table | |
|
| 2 | [SID103227081] | Active | Ki | 0.0038 | Binding affinity against human vasopressin V1a receptor was determined by using plasma membranes from CHO cells stably transfected with VP/OT receptors [AID217087, Type: Literature] | | View X | Row No. | 2 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Active | | Ki | 0.0038 [uM] | | BioAssay | Binding affinity against human vasopressin V1a receptor was determined by using plasma membranes from CHO cells stably transfected with VP/OT receptors | | AID | 217087 | | BioAssay type | Literature | | Target | | | PubMed | 15084136 | | Data Table | |
|
| 3 | [SID103227081] | Active | Ki | 0.005 | Binding affinity against human vasopressin V2 receptor was determined by using plasma membranes from CHO cells stably transfected with VP/OT receptors [AID217394, Type: Literature] | | View X | Row No. | 3 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Active | | Ki | 0.005 [uM] | | BioAssay | Binding affinity against human vasopressin V2 receptor was determined by using plasma membranes from CHO cells stably transfected with VP/OT receptors | | AID | 217394 | | BioAssay type | Literature | | Target | | | PubMed | 15084136 | | Data Table | |
|
| 4 | [SID103227081] | Active | Ki | 0.005 | Binding affinity against human oxytocin receptor was determined by using plasma membranes from CHO cells stably transfected with VP/OT receptors [AID151798, Type: Literature] | | View X | Row No. | 4 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Active | | Ki | 0.005 [uM] | | BioAssay | Binding affinity against human oxytocin receptor was determined by using plasma membranes from CHO cells stably transfected with VP/OT receptors | | AID | 151798 | | BioAssay type | Literature | | Target | | | PubMed | 15084136 | | Data Table | |
|
| 5 | [SID103227081] | Active | | | Tested for intravenous anti-oxytocic effect in the absence of Mg2+ in rats; agonist at concentration of 47 units/kg [AID197143, Type: Literature] | | View X | Row No. | 5 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Active | | BioAssay | Tested for intravenous anti-oxytocic effect in the absence of Mg2+ in rats; agonist at concentration of 47 units/kg | | AID | 197143 | | BioAssay type | Literature | | Target | | | PubMed | 6892930 | | Data Table | |
|
| 6 | [SID103227081] | Active | | | Tested for intravenous anti-vasopressor pA2 effect in rats; agonist at concentration of 346 units/kg [AID197147, Type: Literature] | | View X | Row No. | 6 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Active | | BioAssay | Tested for intravenous anti-vasopressor pA2 effect in rats; agonist at concentration of 346 units/kg | | AID | 197147 | | BioAssay type | Literature | | Target | | | PubMed | 6892930 | | Data Table | |
|
| 7 | [SID85209724] | Active | | | Ligands of peptide (Class A) GPCRs [AID2063, Type: other] | | View X | Row No. | 7 | | Structure |
| | Substance | | | SID | 85209724 | | CID | 27991 | | Outcome | Active | | BioAssay | Ligands of peptide (Class A) GPCRs | | AID | 2063 | | BioAssay type | other | | Target | | | PubMed | | | Data Table | |
|
| 8 | [SID103227081] | Unspecified | | | Bioavailability in rat administered i.d. [AID14033, Type: Literature] | | View X | Row No. | 8 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Unspecified | | BioAssay | Bioavailability in rat administered i.d. | | AID | 14033 | | BioAssay type | Literature | | Target | | | PubMed | 7837227 | | Data Table | |
|
| 9 | [SID103227081] | Unspecified | | | Transport rate in vitro over rat small intestine. [AID21073, Type: Literature] | | View X | Row No. | 9 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Unspecified | | BioAssay | Transport rate in vitro over rat small intestine. | | AID | 21073 | | BioAssay type | Literature | | Target | | | PubMed | 7837227 | | Data Table | |
|
| 10 | [SID103227081] | Unspecified | | | Degradation in vitro by alpha-chymotrypsin. [AID24696, Type: Literature] | | View X | Row No. | 10 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Unspecified | | BioAssay | Degradation in vitro by alpha-chymotrypsin. | | AID | 24696 | | BioAssay type | Literature | | Target | | | PubMed | 7837227 | | Data Table | |
|
| 11 | [SID103227081] | Unspecified | | | Degradation in vitro by rat intestinal juice. [AID24697, Type: Literature] | | View X | Row No. | 11 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Unspecified | | BioAssay | Degradation in vitro by rat intestinal juice. | | AID | 24697 | | BioAssay type | Literature | | Target | | | PubMed | 7837227 | | Data Table | |
|
| 12 | [SID103227081] | Unspecified | | | Half life administered intravenously in rats. [AID25135, Type: Literature] | | View X | Row No. | 12 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Unspecified | | BioAssay | Half life administered intravenously in rats. | | AID | 25135 | | BioAssay type | Literature | | Target | | | PubMed | 7837227 | | Data Table | |
|
| 13 | [SID103227081] | Unspecified | | | Compound was tested for its antidiuretic activity [AID168452, Type: Literature] | | View X | Row No. | 13 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Unspecified | | BioAssay | Compound was tested for its antidiuretic activity | | AID | 168452 | | BioAssay type | Literature | | Target | | | PubMed | 2909737 | | Data Table | |
|
| 14 | [SID103227081] | Unspecified | | | The compound was tested for milk ejection activity in rat [AID171590, Type: Literature] | | View X | Row No. | 14 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Unspecified | | BioAssay | The compound was tested for milk ejection activity in rat | | AID | 171590 | | BioAssay type | Literature | | Target | | | PubMed | 6187921 | | Data Table | |
|
| 15 | [SID103227081] | Unspecified | | | Uterotonic activity in vitro in isolated rat uterus in absence of magnesium [AID171775, Type: Literature] | | View X | Row No. | 15 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Unspecified | | BioAssay | Uterotonic activity in vitro in isolated rat uterus in absence of magnesium | | AID | 171775 | | BioAssay type | Literature | | Target | | | PubMed | 6187921 | | Data Table | |
|
| 16 | [SID103227081] | Unspecified | | | Uterotonic activity in vitro in isolated rat uterus in pressence of magnesium [AID171776, Type: Literature] | | View X | Row No. | 16 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Unspecified | | BioAssay | Uterotonic activity in vitro in isolated rat uterus in pressence of magnesium | | AID | 171776 | | BioAssay type | Literature | | Target | | | PubMed | 6187921 | | Data Table | |
|
| 17 | [SID103227081] | Unspecified | | | Antidiuretic activity on water loaded, ethanol-anesthetized rat. [AID172982, Type: Literature] | | View X | Row No. | 17 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Unspecified | | BioAssay | Antidiuretic activity on water loaded, ethanol-anesthetized rat. | | AID | 172982 | | BioAssay type | Literature | | Target | | | PubMed | 3612693 | | Data Table | |
|
| 18 | [SID103227081] | Unspecified | | | Cmax value administered intraintestinal in rats. [AID13674, Type: Literature] | | View X | Row No. | 18 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Unspecified | | BioAssay | Cmax value administered intraintestinal in rats. | | AID | 13674 | | BioAssay type | Literature | | Target | | | PubMed | 7837227 | | Data Table | |
|
| 19 | [SID103227081] | Unspecified | | | Area under the curve administered intravenously in rats. [AID10731, Type: Literature] | | View X | Row No. | 19 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Unspecified | | BioAssay | Area under the curve administered intravenously in rats. | | AID | 10731 | | BioAssay type | Literature | | Target | | | PubMed | 7837227 | | Data Table | |
|
| 20 | [SID103227081] | Unspecified | | | Dose that reduces the response seen with 2x units of agonist to equal the response seen with 1x unit of agonist administered before antagonist; Agonist [AID173421, Type: Literature] | | View X | Row No. | 20 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Unspecified | | BioAssay | Dose that reduces the response seen with 2x units of agonist to equal the response seen with 1x unit of agonist administered before antagonist; Agonist | | AID | 173421 | | BioAssay type | Literature | | Target | | | PubMed | 2909737 | | Data Table | |
|
| 21 | [SID103227081] | Unspecified | | | Pressor activity on urethane-anesthetized, phenoxybenzamine-treated rat. [AID188190, Type: Literature] | | View X | Row No. | 21 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Unspecified | | BioAssay | Pressor activity on urethane-anesthetized, phenoxybenzamine-treated rat. | | AID | 188190 | | BioAssay type | Literature | | Target | | | PubMed | 3612693 | | Data Table | |
|
| 22 | [SID103227081] | Unspecified | | | Uterine activity was meseared in isolated rat uterus in solutions in the absence No Mg2+ 0.5 mM in vitro [AID191517, Type: Literature] | | View X | Row No. | 22 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Unspecified | | BioAssay | Uterine activity was meseared in isolated rat uterus in solutions in the absence No Mg2+ 0.5 mM in vitro | | AID | 191517 | | BioAssay type | Literature | | Target | | | PubMed | 3612693 | | Data Table | |
|
| 23 | [SID103227081] | Unspecified | Kd | | In vitro anti-oxytocic activity on isolated estrogen treated rat uteri with 0.5 mM Mg+2 [AID196846, Type: Literature] | | View X | Row No. | 23 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Unspecified | | Kd | [uM] | | BioAssay | In vitro anti-oxytocic activity on isolated estrogen treated rat uteri with 0.5 mM Mg+2 | | AID | 196846 | | BioAssay type | Literature | | Target | | | PubMed | 2909737 | | Data Table | |
|
| 24 | [SID103227081] | Unspecified | | | In vitro anti-oxytocic activity on isolated estrogen treated rat uteri without Mg+2; Agonist [AID196969, Type: Literature] | | View X | Row No. | 24 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Unspecified | | BioAssay | In vitro anti-oxytocic activity on isolated estrogen treated rat uteri without Mg+2; Agonist | | AID | 196969 | | BioAssay type | Literature | | Target | | | PubMed | 2909737 | | Data Table | |
|
| 25 | [SID103227081] | Unspecified | | | Tested for the ratio of antidiuretic potency to uterotonic potency(A/O) [AID230130, Type: Literature] | | View X | Row No. | 25 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Unspecified | | BioAssay | Tested for the ratio of antidiuretic potency to uterotonic potency(A/O) | | AID | 230130 | | BioAssay type | Literature | | Target | | | PubMed | 6187921 | | Data Table | |
|
| 26 | [SID103227081] | Unspecified | | | Tested for the ratio of antidiuretic potency to uterotonic potency(A/P) [AID230132, Type: Literature] | | View X | Row No. | 26 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Unspecified | | BioAssay | Tested for the ratio of antidiuretic potency to uterotonic potency(A/P) | | AID | 230132 | | BioAssay type | Literature | | Target | | | PubMed | 6187921 | | Data Table | |
|
| 27 | [SID103227081] | Unspecified | | | Ratio of antidiuretic to vasopressor agonistic activity [AID230907, Type: Literature] | | View X | Row No. | 27 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Unspecified | | BioAssay | Ratio of antidiuretic to vasopressor agonistic activity | | AID | 230907 | | BioAssay type | Literature | | Target | | | PubMed | 2909737 | | Data Table | |
|
| 28 | [SID103227081] | Unspecified | | | Relative transport rate as the ratio of transport rate to that of PEG 1000. [AID232014, Type: Literature] | | View X | Row No. | 28 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Unspecified | | BioAssay | Relative transport rate as the ratio of transport rate to that of PEG 1000. | | AID | 232014 | | BioAssay type | Literature | | Target | | | PubMed | 7837227 | | Data Table | |
|
| 29 | [SID103227081] | Unspecified | | | Relative transport rate as the ratio of transport rate to that of PEG 4000. [AID232015, Type: Literature] | | View X | Row No. | 29 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Unspecified | | BioAssay | Relative transport rate as the ratio of transport rate to that of PEG 4000. | | AID | 232015 | | BioAssay type | Literature | | Target | | | PubMed | 7837227 | | Data Table | |
|
| 30 | [SID103227081] | Unspecified | | | Selectivity index of human V1b receptor towards Oxytocin receptor [AID235492, Type: Literature] | | View X | Row No. | 30 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Unspecified | | BioAssay | Selectivity index of human V1b receptor towards Oxytocin receptor | | AID | 235492 | | BioAssay type | Literature | | Target | | | PubMed | 15084136 | | Data Table | |
|
| 31 | [SID103227081] | Unspecified | | | Selectivity index of human V1b receptor towards V1a receptor [AID235493, Type: Literature] | | View X | Row No. | 31 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Unspecified | | BioAssay | Selectivity index of human V1b receptor towards V1a receptor | | AID | 235493 | | BioAssay type | Literature | | Target | | | PubMed | 15084136 | | Data Table | |
|
| 32 | [SID103227081] | Unspecified | | | Selectivity index of human V1b receptor towards V2 receptor [AID235494, Type: Literature] | | View X | Row No. | 32 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Unspecified | | BioAssay | Selectivity index of human V1b receptor towards V2 receptor | | AID | 235494 | | BioAssay type | Literature | | Target | | | PubMed | 15084136 | | Data Table | |
|
| 33 | [SID103227081] | Unspecified | | | Area under the curve administered intraintestinal in rats. [AID10730, Type: Literature] | | View X | Row No. | 33 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Unspecified | | BioAssay | Area under the curve administered intraintestinal in rats. | | AID | 10730 | | BioAssay type | Literature | | Target | | | PubMed | 7837227 | | Data Table | |
|
| 34 | [SID103227081] | Unspecified | | | Tested for intravenous antidiuretic activity in rats [AID172987, Type: Literature] | | View X | Row No. | 34 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Unspecified | | BioAssay | Tested for intravenous antidiuretic activity in rats | | AID | 172987 | | BioAssay type | Literature | | Target | | | PubMed | 6892930 | | Data Table | |
|
| 35 | [SID103227081] | Unspecified | | | Vasopressin receptor agonistic activity in vivo in rats [AID172988, Type: Literature] | Vasopressin V2 receptor [gi:465020] | View X | Row No. | 35 | | Structure |
| | Substance | | | SID | 103227081 | | CID | 27991 | | Outcome | Unspecified | | BioAssay | Vasopressin receptor agonistic activity in vivo in rats | | AID | 172988 | | BioAssay type | Literature | | Target | Vasopressin V2 receptor [gi:465020] | | PubMed | 7837227 | | Data Table | |
|
Chemical Probe 
Active 
Inactive 
Inconclusive 
Unspecified 
