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2-[(4-methylphenyl)amino]naphthalene-1,4-dione (CID 279009) - Compound BioActivity Data
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BioActivity Outcomes:
Active(9)
 
 
Inactive(13)
 
 
Inconclusive(2)
 
 
BioAssay Types:
Confirmatory(17)
 
 
 
 
BioActivity Types:
AC50(12)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 22    Data Row: 24   Total Pages: 2   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID136349437]
AbsAC40_uM 0.277qPCR Assay for DCT Expression Measured in Cell-Based System Using RT-PCR - 2084-12_Inhibitor_Dose_DryPowder_Activity [AID651771, Type: confirmatory]microphthalmia-associated transcription factor [Homo sapiens] [gi:7684294]
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2
[SID136349437]
AbsAC40_uM 0.745qPCR Assay for MLANA Expression Measured in Cell-Based System Using RT-PCR - 2084-13_Inhibitor_Dose_DryPowder_Activity [AID651795, Type: confirmatory]microphthalmia-associated transcription factor [Homo sapiens] [gi:7684294]
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3
[SID136349437]
AC50_uM 1.24MITF Orthogonal Assay: SK-MEL-5 CTG Assay Measured in Cell-Based System Using Plate Reader - 2084-02_Inhibitor_Dose_DryPowder_Activity_Set7 [AID624428, Type: confirmatory]
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4
[SID136349437]
AbsAC40_uM 1.65qPCR Assay for MITF Expression Measured in Cell-Based System Using RT-PCR - 2084-05_Inhibitor_Dose_DryPowder_Activity [AID651773, Type: confirmatory]microphthalmia-associated transcription factor [Homo sapiens] [gi:7684294]
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5
[SID144221524]
AC50_uM 3.13MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_Dose_DryPowder_Activity_Set10 [AID651753, Type: confirmatory]
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6
[SID136349437]
AC50_uM 6.58MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_Dose_DryPowder_Activity_Set8 [AID624430, Type: confirmatory]
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7
[SID136349437]
AC50_uM 13.54MITF Orthogonal Assay: MALME3 CTG Assay Measured in Cell-Based System Using Plate Reader - 2084-04_Inhibitor_Dose_DryPowder_Activity_Set5 [AID651584, Type: confirmatory]
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8
[SID136349437]
AC50_uM 13.54MITF Orthogonal Assay: MALME3 CTG Assay Measured in Cell-Based System Using Plate Reader - 2084-04_Inhibitor_Dose_DryPowder_Activity_Set6 [AID651585, Type: confirmatory]
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9
[SID136349437]
AC50_uM 36.09MITF Orthogonal Assay: SK-MEL-5 CTG Assay Measured in Cell-Based System Using Plate Reader - 2084-02_Inhibitor_Dose_DryPowder_Activity_Set8 [AID651586, Type: confirmatory]
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10
[SID136349437]
AC50_uM 70MITF: Counter assay: A375 proliferation Measured in Cell-Based System Using Plate Reader - 2084-03_Inhibitor_Dose_DryPowder_Activity_Set9 [AID651591, Type: confirmatory]
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11
[SID136349437]
AC50_uM 70MITF: Counter assay: A375 proliferation Measured in Cell-Based System Using Plate Reader - 2084-03_Inhibitor_Dose_DryPowder_Activity_Set8 [AID624492, Type: confirmatory]
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12
[SID144221524]
AC50_uM 70Primary human melanocyte cytotoxicity assay Measured in Cell-Based System Using Plate Reader - 2084-06_Inhibitor_Dose_DryPowder_Activity [AID651920, Type: confirmatory]
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13
[SID420164]
NCI In Vivo Anticancer Drug Screen. Data for tumor model L1210 Leukemia (intraperitoneal) in B6D2F1 (BDF1) mice [AID248, Type: other]
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14
[SID136349437]
AC50_uM MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_Dose_DryPowder_Activity_Set10 [AID651753, Type: confirmatory]
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15
[SID136349437]
AC50_uM Primary human melanocyte cytotoxicity assay Measured in Cell-Based System Using Plate Reader - 2084-06_Inhibitor_Dose_DryPowder_Activity [AID651920, Type: confirmatory]
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16
[SID136349437]
AC50_uM MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_Dose_DryPowder_Activity_Set9 [AID651588, Type: confirmatory]
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17
[SID420164]
NCI Yeast Anticancer Drug Screen. Data for the rad50 strain [AID155, Type: other]
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18
[SID420164]
NCI Yeast Anticancer Drug Screen. Data for the mec2-1 strain [AID157, Type: other]
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19
[SID420164]
NCI Yeast Anticancer Drug Screen. Data for the sgs1 mgt1 strain [AID161, Type: other]
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20
[SID420164]
NCI Yeast Anticancer Drug Screen. Data for the cln2 rad14 strain [AID165, Type: other]
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