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BioActivity Data for Compound Clioquinol (CID 2788)

BioActivity Outcomes:
Active(268)
 
 
Inactive(1186)
 
 
Inconclusive(340)
 
 
Unspecified(66)
 
 
Top Targets:
7tm 4(52)
 
 
 
 
NR LBD PPAR(27)
 
 
 
 
NR LBD ER(19)
 
 
 
 
NR LBD TR(16)
 
 
 
 
NR LBD AR(16)
 
 
 
 
BioAssay Types:
Confirmatory(757)
 
 
 
 
 
Screening(627)
 
 
 
 
Literature(182)
 
 
 
 
 
Summary(48)
 
 
 
 
BioAssay Categories:
In vitro(2)
 
 
In vivo(5)
 
 
 
Biochemical(148)
 
 
 
 
 
Toxicity(60)
 
 
 
 
 
ADME(19)
 
 
 
Cell-based(185)
 
 
 
Organism-base..(16)
 
 
 
BioActivity Types:
Potency(584)
 
 
 
 
 
IC50(103)
 
 
 
 
 
EC50(34)
 
 
 
AC50(5)
 
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1234    Data Row: 1860   Total Pages: 93   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID170465019]
IC50 0.3453DLD-1 viability from Cell TiterGlo-IC50 [AID1117352, Type: confirmatory]
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2
[SID11112285]
Potency 0.3548qHTS for inhibitors of ROR gamma transcriptional activity [AID2551, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
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3
[SID170465019]
IC50 0.3917HCT116 viability from Cell TiterGlo-IC50 [AID1117332, Type: confirmatory]
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4
[SID855601]
Potency 0.3981qHTS for inhibitors of ROR gamma transcriptional activity [AID2551, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
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5
[SID170465019]
IC50 0.4407SW480 viability from Cell TiterGlo-IC50 [AID1117338, Type: confirmatory]
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6
[SID170465019]
IC50 0.4751SNU-C1 viability from Cell TiterGlo-IC50 [AID1117323, Type: confirmatory]
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7
[SID17389542]
Potency 0.5012VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity [AID2546, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
View
8
[SID170465019]
IC50 0.5862Colo320 viability from Cell TiterGlo-IC50 [AID1117334, Type: confirmatory]
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9
[SID85148761]
AC50_uM 0.619Anti-Malarial Hsp90 Inhibitors Measured in Microorganism System Using Plate Reader - 2121-01_Inhibitor_Dose_CherryPick_Activity [AID540268, Type: confirmatory]HSP90 [Plasmodium falciparum 3D7] [gi:124809506]
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10
[SID85148761]
AbsAC1000_uM 0.629In vivo-based yeast HTS to detect compounds rescuing yeast growth/survival of Plasmodium Falciparum HSP40-mediated toxicity Measured in Whole Organism System Using Plate Reader - 2120-01_Inhibitor_Dose_CherryPick_Activity [AID540271, Type: confirmatory]HSP40, subfamily A, putative [Plasmodium falciparum 3D7] [gi:124809271]
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11
[SID17389542]
Potency 0.631qHTS for inhibitors of ROR gamma transcriptional activity [AID2551, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
View
12
[SID144207489]
Ratio Potency (uM) 0.690651qHTS assay for small molecule activators of the heat shock response signaling pathway: Summary [AID743228, Type: summary]heat shock protein beta-1 [Homo sapiens] [gi:4504517]
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13
[SID26746922]
Potency 0.8913qHTS for inhibitors of ROR gamma transcriptional activity [AID2551, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
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14
[SID144203967]
Potency-Replicate_1 0.9439qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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15
[SID855601]
EC50_MICROM 0.986Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically LAP4 based on MLPCN hits [AID2745, Type: confirmatory]LAP4 [Saccharomyces cerevisiae] [gi:486173]
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16
[SID855601]
Potency 1VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity [AID2546, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
View
17
[SID85148761]
AC50_uM 1.158HsHsp90 Counterscreen Measured in Microorganism System Using Plate Reader - 2121-02_Inhibitor_Dose_CherryPick_Activity [AID540270, Type: confirmatory]heat shock protein HSP 90-alpha isoform 2 [Homo sapiens] [gi:154146191]
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18
[SID85148761]
AbsAC35_uM 1.67Cell-based secondary assay to test the inhibitory activity of small molecule on Plasmodium flaciparum (HB3 strain) survival in red blood cells Measured in Cell-Based System Using Plate Reader - 2120-06_Inhibitor_Dose_CherryPick_Activity [AID652041, Type: confirmatory]
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19
[SID103171270]
CC50 2Cytotoxicity against PBMC [AID276977, Type: Literature]
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20
[SID85148761]
AbsAC35_uM 2.33Cell-based secondary assay to test the inhibitory activity of small molecule on Plasmodium flaciparum (3D7 strain) survival in red blood cells Measured in Cell-Based System Using Plate Reader - 2120-05_Inhibitor_Dose_CherryPick_Activity [AID652047, Type: confirmatory]
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