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BioActivity Data for Compound Ethionamide (CID 2761171)

BioActivity Outcomes:
Active(17)
 
 
Inactive(1843)
 
 
Inconclusive(89)
 
 
Unspecified(1290)
 
 
Top Targets:
7tm 4(71)
 
 
NR LBD PPAR(40)
 
 
 
NR LBD ER(25)
 
 
 
 
NR LBD AR(25)
 
 
 
NR LBD TR(23)
 
 
 
BioAssay Types:
Confirmatory(875)
 
 
 
 
 
Screening(767)
 
 
 
 
Literature(214)
 
 
 
 
 
Summary(87)
 
 
 
BioAssay Categories:
In vitro(4)
 
 
 
In vivo(1187)
 
 
 
Biochemical(225)
 
 
Toxicity(1279)
 
 
 
 
ADME(26)
 
 
Cell-based(231)
 
 
 
 
Organism-base..(23)
 
 
 
BioActivity Types:
Potency(798)
 
 
 
 
 
IC50(71)
 
 
 
 
AC50(12)
 
 
 
EC50(8)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 2296    Data Row: 3239   Total Pages: 162   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144209607]
Potency-Replicate_1 5.3984qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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2
[SID103512882]
IC50 6.75Antimycobacterial activity against Mycobacterium smegmatis by GFP-based fluorescence assay [AID562239, Type: Literature]
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3
[SID103512882]
IC50 7.66Antimycobacterial activity against Mycobacterium smegmatis assessed as growth inhibition in mid-logarithmic phase by spectrophotometry [AID562238, Type: Literature]
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4
[SID85148756]
IC50 (with Meropenem) 8.455Screen and Counter Screen to Identify Novel Compounds that Selectively Sensitize Mycobacterium Tuberculosis to Beta-lactam Antibiotics [AID434987, Type: confirmatory]
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5
[SID85148756]
IC90 12.788Screen to Identify Novel Compounds That Sensitize Mycobacterium Tuberculosis to Beta-lactam Antibiotics [AID434955, Type: confirmatory]
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6
[SID103512882]
Inhibition of mycolic acid synthesis in Mycobacterium bovis BCG NCTC 5692 with ethR-knockout mutant assessed as incorporation of [2-14C]acetate [AID283665, Type: Literature]
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7
[SID49698701]
High Throughput Screen to Identify Inhibitors of Mycobacterium tuberculosis H37Rv [AID1332, Type: confirmatory]
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8
[SID48415974]
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
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9
[SID48413732]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
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10
[SID48413732]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Mouse Bioassay Results [AID1199, Type: other]
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11
[SID103512882]
IC50 Antimycobacterial activity against Mycobacterium tuberculosis H37Rv after 6 days by MTT assay [AID649473, Type: Literature]
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12
[SID103512882]
Antimycobacterial activity against Mycobacterium tuberculosis H37Rv [AID713897, Type: Literature]
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13
[SID11532957]
uHTS of Mcl-1/Noxa interaction inhibitors [AID1022, Type: screening]Mcl-1 [Homo sapiens] [gi:7582271]
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14
[SID11112402]
p450-cyp1a2 [AID410, Type: confirmatory]cytochrome P450 1A2 [Homo sapiens] [gi:73915100]
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15
[SID103512882]
Enoyl-[acyl-carrier-protein] reductase inhibitor [AID742802, Type: Literature]Enoyl-[acyl-carrier-protein] reductase [NADH] [gi:614084752]
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16
[SID103512882]
Enoyl-[acyl-carrier-protein] reductase inhibitor [AID742802, Type: Literature]Enoyl-[acyl-carrier-protein] reductase [NADH] [gi:614084752]
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17
[SID103512882]
Enoyl-[acyl-carrier-protein] reductase inhibitor [AID742802, Type: Literature]Enoyl-[acyl-carrier-protein] reductase [NADH] [gi:614084752]
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18
[SID85148756]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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19
[SID56422118]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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20
[SID103512882]
Antimicrobial activity against Mycobacterium chelonae ATCC 35752 by resazurine microtiter assay [AID565228, Type: Literature]
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