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BioActivity Data for Compound eucalyptol (CID 2758)

BioActivity Outcomes:
Active(13)
 
 
Inactive(1063)
 
 
Inconclusive(46)
 
 
Unspecified(427)
 
 
Top Targets:
7tm 4(58)
 
 
 
NR LBD PPAR(29)
 
 
 
NR LBD ER(25)
 
 
 
NR LBD AR(24)
 
 
 
 
p450(18)
 
 
 
BioAssay Types:
Confirmatory(710)
 
 
 
 
 
Screening(321)
 
 
 
 
Literature(203)
 
 
 
 
Summary(72)
 
 
 
BioActivity Types:
Potency(519)
 
 
 
 
 
IC50(132)
 
 
 
EC50(5)
 
 
AC50(3)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1197    Data Row: 1549   Total Pages: 78   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144209288]
AhR Potency (uM) 49.7911qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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2
[SID47193678]
MLPCN Streptokinase Expression Inhibition [AID1662, Type: screening]streptokinase A [Streptococcus pyogenes M1 GAS] [gi:15675770]
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3
[SID103618726]
Contact insecticidal activity against cotton leafworm Spodoptera littoralis third-instar larvae exposed to 1 mg/larva compound application through dorsum of larvae followed by feeding on fresh castor bean leaves assessed as insect mortality after 24 hr [AID1108166, Type: other]
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4
[SID103618726]
Induction of LXR-responsive genes in mouse RAW264.7 cells assessed as increase in Abca1 mRNA expression measured at 50 to 100 microM by qPCR [AID727627, Type: Literature]
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5
[SID103618726]
Reduction in lipid accumulation in human HepG2 cells at 100 microM by Oil Red O staining [AID727621, Type: Literature]
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6
[SID103618726]
Reduction in lipid accumulation in human HepG2 cells at 50 microM by Oil Red O staining [AID727622, Type: Literature]
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7
[SID103618726]
Induction of LXR-responsive genes in mouse RAW264.7 cells assessed as increase in ABCA1 protein expression measured at 100 microM by immunoblotting [AID727623, Type: Literature]
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8
[SID103618726]
Induction of cholesterol efflux genes in mouse RAW264.7 cells assessed as increase in LXRbeta protein expression measured at 100 microM by immunoblotting [AID727624, Type: Literature]
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9
[SID103618726]
Induction of cholesterol efflux genes in mouse RAW264.7 cells assessed as increase in LXRalpha protein expression measured at 100 microM by immunoblotting [AID727625, Type: Literature]
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10
[SID103618726]
Induction of LXR-responsive genes in mouse RAW264.7 cells assessed as increase in Abca2 mRNA expression measured at 50 to 100 microM by qPCR [AID727626, Type: Literature]
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11
[SID48415229]
DSSTox (EPAFHM) EPA Fathead Minnow Acute Toxicity [AID1188, Type: other]
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12
[SID72164]
NCI human tumor cell line growth inhibition assay. Data for the MCF7 Breast cell line [AID83, Type: confirmatory]
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13
[SID72164]
NCI human tumor cell line growth inhibition assay. Data for the A498 Renal cell line [AID129, Type: confirmatory]
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14
[SID17389880]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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15
[SID8149342]
Assay to identify inhibitors of polyglutamine-induced caspase-3 activation (CASP3) [AID1583, Type: other]
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16
[SID103618726]
Inhibition of COX2 at 100 uM by scintillation proximity assay [AID336478, Type: Literature]
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17
[SID17389880]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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18
[SID8149342]
Screen for compounds that increase glutamate transport activity in MN-1 cell line (GluUPTAKE) [AID1612, Type: other]
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19
[SID8149342]
Screen for compounds that selectively inhibit cytochrome c release from purified mitochondria (CytoCRel) [AID1603, Type: other]
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20
[SID8149342]
Screen for compounds that inhibit polyglutamine induced protein aggregation (AGREG) [AID1604, Type: other]
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