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BioActivity Data for Compound eucalyptol (CID 2758)

BioActivity Outcomes:
Active(13)
 
 
Inactive(1097)
 
 
Inconclusive(50)
 
 
Unspecified(429)
 
 
Top Targets:
7tm 4(57)
 
 
 
NR LBD PPAR(29)
 
 
 
NR LBD ER(25)
 
 
 
NR LBD AR(24)
 
 
 
 
p450(18)
 
 
 
BioAssay Types:
Confirmatory(739)
 
 
 
 
 
Screening(322)
 
 
 
 
Literature(203)
 
 
 
 
Summary(81)
 
 
 
 
BioAssay Categories:
In vitro(133)
 
 
 
In vivo(164)
 
 
 
Biochemical(246)
 
 
 
Toxicity(225)
 
 
 
 
 
Cell-based(227)
 
 
 
 
 
Organism-base..(18)
 
 
 
BioActivity Types:
Potency(554)
 
 
 
 
 
IC50(132)
 
 
 
AC50(6)
 
 
 
EC50(5)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1214    Data Row: 1589   Total Pages: 80   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144209288]
AhR Potency (uM) 49.7911qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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2
[SID47193678]
MLPCN Streptokinase Expression Inhibition [AID1662, Type: screening]streptokinase A [Streptococcus pyogenes M1 GAS] [gi:15675770]
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3
[SID48415229]
DSSTox (EPAFHM) EPA Fathead Minnow Acute Toxicity [AID1188, Type: other]
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4
[SID103618726]
Reduction in lipid accumulation in human HepG2 cells at 100 microM by Oil Red O staining [AID727621, Type: Literature]
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5
[SID103618726]
Reduction in lipid accumulation in human HepG2 cells at 50 microM by Oil Red O staining [AID727622, Type: Literature]
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6
[SID103618726]
Induction of LXR-responsive genes in mouse RAW264.7 cells assessed as increase in ABCA1 protein expression measured at 100 microM by immunoblotting [AID727623, Type: Literature]
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7
[SID103618726]
Induction of cholesterol efflux genes in mouse RAW264.7 cells assessed as increase in LXRbeta protein expression measured at 100 microM by immunoblotting [AID727624, Type: Literature]
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8
[SID103618726]
Induction of cholesterol efflux genes in mouse RAW264.7 cells assessed as increase in LXRalpha protein expression measured at 100 microM by immunoblotting [AID727625, Type: Literature]
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9
[SID103618726]
Induction of LXR-responsive genes in mouse RAW264.7 cells assessed as increase in Abca2 mRNA expression measured at 50 to 100 microM by qPCR [AID727626, Type: Literature]
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10
[SID103618726]
Induction of LXR-responsive genes in mouse RAW264.7 cells assessed as increase in Abca1 mRNA expression measured at 50 to 100 microM by qPCR [AID727627, Type: Literature]
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11
[SID103618726]
Contact insecticidal activity against cotton leafworm Spodoptera littoralis third-instar larvae exposed to 1 mg/larva compound application through dorsum of larvae followed by feeding on fresh castor bean leaves assessed as insect mortality after 24 hr [AID1108166, Type: other]
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12
[SID72164]
NCI human tumor cell line growth inhibition assay. Data for the MCF7 Breast cell line [AID83, Type: confirmatory]
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13
[SID72164]
NCI human tumor cell line growth inhibition assay. Data for the A498 Renal cell line [AID129, Type: confirmatory]
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14
[SID17389880]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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15
[SID103618726]
Fumigant insecticidal activity against cotton leafworm Spodoptera littoralis third-instar larvae fed on fresh castor bean leaves assessed as insect mortality after 24 hr [AID1108167, Type: other]
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16
[SID103618726]
Fumigant molluscicidal activity against Theba pisana (white garden snail) assessed as snail mortality after 24 hr [AID1108168, Type: other]
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17
[SID103618726]
Contact molluscicidal activity against Theba pisana (white garden snail ) exposed to compound throgh application to surface of snail body inside shell assessed as compound level per snail causing snail mortality after 24 hr [AID1108169, Type: other]
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18
[SID103618726]
Antimicrobial activity against Corticium sp. assessed as inhibition of mycelial growth on potato dextrose agar at 1000 ppm at 27 degC measured after 4 days [AID1108696, Type: other]
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19
[SID103618726]
Antimicrobial activity against Corticium sp. assessed as inhibition of mycelial growth on potato dextrose agar at 100 ppm at 27 degC measured after 4 days [AID1108697, Type: other]
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20
[SID103618726]
Antimicrobial activity against Pythium sp. assessed as inhibition of mycelial growth on potato dextrose agar at 1000 ppm at 27 degC measured after 4 days [AID1108698, Type: other]
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