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NSC119913 (CID 274125) - Compound BioActivity Data
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BioActivity Outcomes:
Active(9)
 
 
Inactive(67)
 
 
Unspecified(6)
 
 
Top Targets:
HSPA1-2 6-8-l..(2)
 
 
CAP ED(1)
 
 
RNase HI euka..(1)
 
 
RNase HI prok..(1)
 
 
RVT connect(1)
 
 
BioAssay Types:
Confirmatory(62)
 
 
 
 
Literature(8)
 
 
 
 
Screening(3)
 
 
BioActivity Types:
IC50(4)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 81    Data Row: 82   Total Pages: 5   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID26514300]
IC50 0.634In Vitro Hsp70 Dose Response Fluorescence Polarization Assay for SAR Study [AID1072, Type: confirmatory]heat shock 70kDa protein 1A [Homo sapiens] [gi:123271505]
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2
[SID26514300]
IC50 5.58In Vitro Hsc70 Dose Response Fluorescence Polarization Assay [AID1193, Type: confirmatory]heat shock cognate 71 kDa protein isoform 1 [Homo sapiens] [gi:5729877]
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3
[SID26514300]
IC50 5.58In Vitro Hsc70 Dose Response Fluorescence Polarization Assay [AID1193, Type: confirmatory]heat shock cognate 71 kDa protein isoform 2 [Homo sapiens] [gi:24234686]
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4
[SID103649564]
IC50 43Inhibition of Escherichia coli MurD assessed as blockade of addition of D-[14C]Glu to UDP-MurNAc-L-Ala [AID393934, Type: Literature]
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5
[SID414518]
NCI human tumor cell line growth inhibition assay. Data for the CCRF-CEM Leukemia cell line [AID119, Type: confirmatory]
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6
[SID8139588]
HIV-2 RNase H Inhibition [AID367, Type: screening]Chain A, Crystal Structure Of Hiv-2 Reverse Transcriptase [gi:24987805]
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7
[SID8139588]
E. coli RNase H Inhibition [AID365, Type: screening]Ribonuclease HI [gi:67472286]
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8
[SID8139588]
human RNase H Inhibition [AID366, Type: screening]ribonuclease H1 isoform 1 precursor [Homo sapiens] [gi:21359816]
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9
[SID103649564]
Reversible inhibition of recombinant phosphatase activity of Cdc25B catalytic domain expressed in Escherichia coli BL21(DE3) assessed as residual activity of enzyme measured after 10 fold dilution at 100 uM preincubated for 20 mins [AID673291, Type: Literature]
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10
[SID103649564]
Inhibition of recombinant phosphatase activity of Cdc25B catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate at 100 uM after 15 mins by fluorimetric assay [AID673289, Type: Literature]
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11
[SID103649564]
Inhibition of recombinant phosphatase activity of Cdc25C catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate at 100 uM after 15 mins by fluorimetric assay [AID673290, Type: Literature]
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12
[SID414518]
NCI AIDS Antiviral Assay [AID179, Type: confirmatory]
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13
[SID103649564]
Inhibition of recombinant phosphatase activity of Cdc25A catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate at 100 uM after 15 mins by fluorimetric assay [AID673288, Type: Literature]
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14
[SID414518]
NCI human tumor cell line growth inhibition assay. Data for the SNB-75 Central Nervous System cell line [AID55, Type: confirmatory]
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15
[SID414518]
NCI human tumor cell line growth inhibition assay. Data for the NCI-H522 Non-Small Cell Lung cell line [AID15, Type: confirmatory]
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16
[SID414518]
NCI human tumor cell line growth inhibition assay. Data for the A549/ATCC Non-Small Cell Lung cell line [AID19, Type: confirmatory]
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17
[SID414518]
NCI human tumor cell line growth inhibition assay. Data for the EKVX Non-Small Cell Lung cell line [AID21, Type: confirmatory]
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18
[SID414518]
NCI human tumor cell line growth inhibition assay. Data for the LOX IMVI Melanoma cell line [AID23, Type: confirmatory]
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19
[SID414518]
NCI human tumor cell line growth inhibition assay. Data for the M14 Melanoma cell line [AID25, Type: confirmatory]
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20
[SID414518]
NCI human tumor cell line growth inhibition assay. Data for the UACC-62 Melanoma cell line [AID31, Type: confirmatory]
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