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BioActivity Data for Compound Tamoxifen (CID 2733525)

BioActivity Outcomes:
Active(378)
 
 
Inactive(960)
 
 
Inconclusive(454)
 
 
Unspecified(51)
 
 
Top Targets:
7tm 4(42)
 
 
 
NR LBD PPAR(34)
 
 
 
 
NR LBD ER(29)
 
 
 
 
 
p450(28)
 
 
 
 
NR LBD AR(25)
 
 
 
 
BioAssay Types:
Confirmatory(947)
 
 
 
 
 
Screening(389)
 
 
 
 
Literature(117)
 
 
 
 
 
Summary(85)
 
 
 
 
BioAssay Categories:
In vitro(3)
 
 
 
In vivo(16)
 
 
 
 
Biochemical(114)
 
 
 
Toxicity(81)
 
 
 
 
 
ADME(5)
 
 
Cell-based(141)
 
 
 
 
 
Organism-base..(14)
 
 
 
BioActivity Types:
Potency(830)
 
 
 
 
 
AC50(23)
 
 
 
IC50(22)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1033    Data Row: 1843   Total Pages: 93   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144210594]
Potency-Replicate_1 0.1096qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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2
[SID144210594]
Potency-Replicate_1 0.3464qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
View
3
[SID144209268]
Potency-Replicate_1 0.4323qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
View
4
[SID144204489]
Potency-Replicate_1 0.5956qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
View
5
[SID170465425]
Ac50 0.968017qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen 4, ratio channel [AID1117308, Type: confirmatory]
View
6
[SID144209268]
Potency-Replicate_1 1.086qHTS assay to identify aromatase inhibitors [AID743083, Type: confirmatory]cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a [Homo sapiens] [gi:119597822]
View
7
[SID170465425]
AC50 (uM) 1.0861qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 3 ratio channel [AID1117300, Type: confirmatory]
View
8
[SID170465425]
Ac50 1.08613qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen 3, ratio channel [AID1117313, Type: confirmatory]
View
9
[SID170465425]
AC50 (uM) 1.122qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 ratio channel [AID1117305, Type: confirmatory]
View
10
[SID170465425]
AC50 (uM) 1.122qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 1 blue channel [AID1117301, Type: confirmatory]
View
11
[SID170465425]
Ac50 1.12202qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen2, ratio channel [AID1117312, Type: confirmatory]
View
12
[SID144209268]
Ratio Potency (uM) 1.13799qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743078, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
13
[SID170465425]
Ac50 1.25893qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen1, ratio channel [AID1117318, Type: confirmatory]
View
14
[SID170465425]
AC50 (uM) 1.26qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 1 ratio channel [AID1117303, Type: confirmatory]
View
15
[SID170465425]
AC50 (uM) 1.4125qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 blue channel [AID1117304, Type: confirmatory]
View
16
[SID144210594]
Potency-Replicate_1 1.5475qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
View
17
[SID170465425]
AC50 (uM) 1.9314qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 3 blue channel [AID1117306, Type: confirmatory]
View
18
[SID144204489]
Ratio Potency (uM) 2.68325qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743078, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
19
[SID144210594]
Potency-Replicate_1 2.7519qHTS assay to identify aromatase inhibitors [AID743083, Type: confirmatory]cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a [Homo sapiens] [gi:119597822]
View
20
[SID17389724]
Potency 2.8184qHTS assay for small molecule antagonists of estrogen receptor alpha signaling [AID588513, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View