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BioActivity Data for Compound Digoxin (CID 2724385)

BioActivity Outcomes:
Active(455)
 
 
Inactive(1217)
 
 
Inconclusive(233)
 
 
Unspecified(523)
 
 
Top Targets:
7tm 4(93)
 
 
 
 
ABC MTABC3 MD..(40)
 
 
 
NR LBD PPAR(34)
 
 
 
NR LBD ER(27)
 
 
 
 
 
NR LBD AR(26)
 
 
 
 
BioAssay Types:
Confirmatory(874)
 
 
 
 
 
Screening(708)
 
 
 
 
Literature(376)
 
 
 
 
 
Summary(67)
 
 
 
 
BioAssay Categories:
In vitro(189)
 
 
 
In vivo(203)
 
 
 
Biochemical(320)
 
 
 
 
 
Toxicity(298)
 
 
 
 
 
ADME(98)
 
 
 
 
Cell-based(433)
 
 
 
 
 
Organism-base..(17)
 
 
BioActivity Types:
Potency(656)
 
 
 
 
 
IC50(242)
 
 
 
 
 
EC50(24)
 
 
 
AC50(5)
 
 
 
 
Ki(4)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1579    Data Row: 2428   Total Pages: 122   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103707689]
Ki 0.0008Binding affinity against Monoclonal antibody mAB-1B3 using [3H]digitoxin as radioligand [AID127357, Type: Literature]
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2
[SID103707689]
Ki 0.0012Binding affinity against Monoclonal antibody mAB-1B3 using [3H]digoxin as radioligand [AID127356, Type: Literature]
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3
[SID103707689]
Kd 0.0031Kinetic parameter against Monoclonal antibody mAB-1B3 [AID127354, Type: Literature]
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4
[SID144204576]
Potency 0.0035qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID720533, Type: confirmatory]
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5
[SID144213367]
Potency-Replicate_1 0.0048qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway - cell viability counter screen [AID743194, Type: confirmatory]
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6
[SID144213367]
Potency-Replicate_1 0.0076qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway - cell viability counter screen [AID743203, Type: confirmatory]
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7
[SID144213367]
Potency-Replicate_1 0.0122qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743218, Type: confirmatory]
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8
[SID144208876]
Potency-Replicate_1 0.0122qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway - cell viability counter screen [AID743203, Type: confirmatory]
View
9
[SID144213367]
Potency-Replicate_1 0.0136qHTS assay to identify small molecule antagonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743225, Type: confirmatory]
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10
[SID144213367]
Potency-Replicate_1 0.0136qHTS assay for small molecule activators of the heat shock response signaling pathway - cell viability counter screen [AID743209, Type: confirmatory]
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11
[SID144213367]
Potency-Replicate_1 0.0136qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743213, Type: confirmatory]
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12
[SID144208876]
Potency-Replicate_1 0.0137qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
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13
[SID103707689]
IC50 0.0146Cytotoxicity against human TK10 cells after 48 hrs by SRB assay [AID399010, Type: Literature]
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14
[SID144208876]
Potency-Replicate_1 0.0155qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway - cell viability counter screen [AID743033, Type: confirmatory]
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15
[SID144208876]
Potency-Replicate_1 0.0174qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
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16
[SID144208876]
Potency-Replicate_1 0.0195qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway - cell viability counter screen [AID743074, Type: confirmatory]
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17
[SID144208876]
Potency-Replicate_1 0.0219qHTS assay to identify small molecule antagonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743225, Type: confirmatory]
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18
[SID144208876]
Potency-Replicate_1 0.0219qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway - cell viability counter screen [AID743194, Type: confirmatory]
View
19
[SID103707689]
IC50 0.0241Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay [AID399011, Type: Literature]
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20
[SID144208876]
Potency-Replicate_1 0.0246qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743213, Type: confirmatory]
View