parbendazole (CID 26596) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(19)
 
 
Inactive(186)
 
 
Inconclusive(19)
 
 
Unspecified(4)
 
 
Top Targets:
p450(10)
 
 
 
 
LDH-like MDH(3)
 
 
 
Firefly Luc l..(3)
 
 
 
HSD10-like SD..(2)
 
 
IMPase(2)
 
 
BioAssay Types:
Confirmatory(105)
 
 
 
 
 
Literature(64)
 
 
 
Screening(22)
 
 
 
BioActivity Types:
Potency(80)
 
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 162    Data Row: 228   Total Pages: 5   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144204122]
Potency 0.057qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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2
[SID144204122]
Potency 0.057qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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3
[SID144204122]
Potency 0.057qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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4
[SID144204122]
Potency 0.0718qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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5
[SID144204122]
Potency 0.0718qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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6
[SID144204122]
Potency 0.0718qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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7
[SID11112614]
Potency 0.1276A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. [AID624297, Type: confirmatory]GMNN gene product [Homo sapiens] [gi:7705682]
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8
[SID11112614]
Potency 0.2389S16 Schwann cell PMP22 intronic element beta-lactamase assay [AID624044, Type: confirmatory]Pmp22 gene product [Rattus norvegicus] [gi:8393992]
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9
[SID49699301]
 Vibrio cholerae assay for pro-quorum sensing small molecules [AID686977, Type: screening]cyclic AMP receptor protein [Vibrio cholerae O1 biovar El Tor str. N16961] [gi:9657203]
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10
[SID85860907]
 Inhibition of P. falciparum 3D7 [AID2306, Type: screening]L-lactate dehydrogenase [Plasmodium falciparum 3D7] [gi:124513266]
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11
[SID85788909]
 Luminescence Cell-Based Primary HTS to Identify Inhibitors of STK33 [AID2330, Type: screening]serine/threonine kinase 33 [Homo sapiens] [gi:12830367]
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12
[SID85788909]
 Luminescence Cell-Based Primary HTS to Identify Inhibitors of STK33 [AID2330, Type: screening]serine/threonine kinase 33 [Homo sapiens] [gi:12830367]
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13
[SID85788909]
 Luminescence Cell-Based Primary HTS to Identify Inhibitors of STK33 [AID2330, Type: screening]serine/threonine kinase 33 [Homo sapiens] [gi:12830367]
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14
[SID11112614]
 Cytochrome panel assay with activity outcomes [AID1851_4, Type: other]cytochrome P450, family 1, subfamily A, polypeptide 2 [Homo sapiens] [gi:73915100]
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15
[SID11112614]
 Cytochrome panel assay with activity outcomes [AID1851_4, Type: other]cytochrome P450, family 1, subfamily A, polypeptide 2 [Homo sapiens] [gi:73915100]
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16
[SID11112614]
 GR-GFP Redistribution [AID450, Type: confirmatory]glucocorticoid receptor isoform gamma [Homo sapiens] [gi:66528677]
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17
[SID11112614]
 GR-GFP Redistribution [AID450, Type: confirmatory]glucocorticoid receptor isoform gamma [Homo sapiens] [gi:66528677]
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18
[SID11112614]
 GR-GFP Redistribution [AID450, Type: confirmatory]glucocorticoid receptor isoform gamma [Homo sapiens] [gi:66528677]
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19
[SID11112614]
 GR-GFP Redistribution [AID450, Type: confirmatory]glucocorticoid receptor isoform gamma [Homo sapiens] [gi:66528677]
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20
[SID138433]
 NCI In Vivo Anticancer Drug Screen. Data for tumor model B16 Melanoma (intraperitoneal) in B6C3F1 mice [AID200, Type: other]
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21
[SID138433]
 NCI In Vivo Anticancer Drug Screen. Data for tumor model Mammary Adenocarcinoma CD8F1 (subcutaneous) in CD8F1 [AID220, Type: other]
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22
[SID138433]
 NCI In Vivo Anticancer Drug Screen. Data for tumor model L1210 Leukemia (intraperitoneal) in B6D2F1 (BDF1) mice [AID248, Type: other]
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23
[SID138433]
 NCI In Vivo Anticancer Drug Screen. Data for tumor model L1210 Leukemia (intraperitoneal) in CD2F1 (CDF1) mice [AID256, Type: other]
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24
[SID138433]
 NCI In Vivo Anticancer Drug Screen. Data for tumor model P388 Leukemia (intraperitoneal) in B6D2F1 (BDF1) mice [AID328, Type: other]
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25
[SID11112614]
 qHTS Assay for Spectroscopic Profiling in 4-MU Spectral Region [AID589, Type: other]
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26
[SID11112614]
 qHTS Assay for Spectroscopic Profiling in A350 Spectral Region [AID590, Type: other]
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27
[SID11112614]
 Cell signaling CRE-BLA (Fsk stim) [AID662, Type: confirmatory]
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28
[SID85788909]
 Luminescence Cell-Based Primary HTS to Measure Viability of BJeLR cells [AID2275, Type: screening]
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29
[SID11112614]
 p450-cyp1a2 [AID410, Type: confirmatory]cytochrome P450, family 1, subfamily A, polypeptide 2 [Homo sapiens] [gi:73915100]
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30
[SID11112614]
 p450-cyp1a2 [AID410, Type: confirmatory]cytochrome P450, family 1, subfamily A, polypeptide 2 [Homo sapiens] [gi:73915100]
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31
[SID11112614]
 p450-cyp1a2 [AID410, Type: confirmatory]cytochrome P450, family 1, subfamily A, polypeptide 2 [Homo sapiens] [gi:73915100]
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32
[SID85860907]
XC50_3D7 0.68XC50 for P. falciparum 3D7 [AID2305, Type: confirmatory]
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33
[SID85860907]
 Inhibition Frequency Index [AID2297, Type: other]
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34
[SID11112614]
 Cytochrome panel assay with activity outcomes [AID1851, Type: other]cytochrome P450, family 2, subfamily C, polypeptide 19 [Homo sapiens] [gi:4503219]
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35
[SID11112614]
 Cytochrome panel assay with activity outcomes [AID1851, Type: other]cytochrome P450, family 2, subfamily C, polypeptide 19 [Homo sapiens] [gi:4503219]
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36
[SID11112614]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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37
[SID11112614]
Potency 0.1qHTS Assay for Compounds that Induce Erasure of Genomic Imprints [AID1948, Type: confirmatory]
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38
[SID11112614]
Potency 1.0182Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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39
[SID11112614]
Potency 1.5472S16 Schwann cell PMP22 intronic element firefly luciferase assay [AID624032, Type: confirmatory]Pmp22 gene product [Rattus norvegicus] [gi:8393992]
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40
[SID11112614]
Potency 1.8106Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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41
[SID85788909]
 Luminescence Cell-Based Primary HTS to Identify Inhibitors of the Sonic Hedgehog Signaling Pathway [AID2313, Type: screening]
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42
[SID85788909]
 Luminescence Homogenous Primary HTS to Identify Inhibitors of STK33 Activity [AID2322, Type: screening]
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43
[SID49699301]
 High Throughput Screen to Identify Inhibitors of Mycobacterium tuberculosis H37Rv [AID1332, Type: confirmatory]
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44
[SID85788909]
 Fluorescence Cell-Based Primary HTS to Measure Inhibition of Y box Binding Protein 1 Expression [AID434959, Type: screening]
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45
[SID85860907]
 Inhibition of HepG2 cell line [AID2303, Type: screening]
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46
[SID11112614]
Potency S16 Schwann cell viability assay (CellTiter-Glo assay) [AID624031, Type: confirmatory]
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47
[SID85788909]
 Fluorescence Cell-Based Primary HTS to Identify Reactive Oxygen Species Inducers in Cancer Cells Measured in Cell-Based System Using Plate Reader and Imaging Combination - 2044-01_Activator_SinglePoint_HTS_Activity [AID624156, Type: screening]
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48
[SID103914649]
 Screening small molecules to find regulators of human embryonic stem cell survival. [AID493140, Type: screening]
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49
[SID121363737]
 A screen for compounds that inhibit liver stage malaria [AID624349, Type: other]
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50
[SID11112614]
Potency qHTS Assay for Inhibitors of Firefly Luciferase [AID411, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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