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Butyric Acid (CID 264) - Compound BioActivity Data
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BioActivity Outcomes:
Active(20)
 
 
Inactive(176)
 
 
Inconclusive(15)
 
 
Unspecified(76)
 
 
Top Targets:
NR LBD PPAR(16)
 
 
 
NR LBD ER(14)
 
 
 
NR LBD AR(14)
 
 
NR LBD Fxr(8)
 
 
NR LBD GR(8)
 
 
BioAssay Types:
Confirmatory(124)
 
 
 
Literature(97)
 
 
 
 
Summary(48)
 
 
 
BioActivity Types:
Potency(160)
 
 
 
IC50(20)
 
 
 
Ki(6)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 198    Data Row: 287   Total Pages: 15   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103176198]
IC50 9Inhibition of human recombinant HDAC3 [AID569930, Type: Literature]Histone deacetylase 3 [gi:3334210]
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2
[SID103176198]
IC50 12Inhibition of human recombinant HDAC2 [AID569929, Type: Literature]Histone deacetylase 2 [gi:68068066]
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3
[SID103176198]
IC50 15Inhibition of human recombinant HDAC8 [AID569931, Type: Literature]Histone deacetylase 8 [gi:29839394]
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4
[SID103176198]
IC50 16Inhibition of human recombinant HDAC1 [AID569928, Type: Literature]Histone deacetylase 1 [gi:2498443]
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5
[SID46393305]
Ki 1300Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Crystal Structure Of Co-Type Nitrile Hydratase Complexed With N-Butyric Acid [gi:50513824]
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6
[SID46393305]
Ki 1300Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Crystal Structure Of Co-Type Nitrile Hydratase Complexed With N-Butyric Acid [gi:50513824]
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7
[SID46393305]
Ki 1300Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain B, Crystal Structure Of Co-Type Nitrile Hydratase Complexed With N-Butyric Acid [gi:50513825]
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8
[SID46393305]
Ki 1300Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain B, Crystal Structure Of Co-Type Nitrile Hydratase Complexed With N-Butyric Acid [gi:50513825]
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9
[SID74110]
NCI In Vivo Anticancer Drug Screen. Data for tumor model Mammary Adenocarcinoma CD8F1 (subcutaneous) in CD8F1 [AID220, Type: other]
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10
[SID103176198]
Inhibition of HDAC in human MDA-MB-231 cells assessed as increase in p21 mRNA level by qRT-PCR [AID412897, Type: Literature]
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11
[SID103176198]
Inhibition of HDAC in human MDA-MB-231 cells assessed as increase in histone H3 acetylation after 3 days by densitometry [AID412899, Type: Literature]
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12
[SID103176198]
Increase in ROS production in human U251 cells at 100 uM after 4 hrs by FACS [AID347396, Type: Literature]
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13
[SID103176198]
Increase in ROS production in human U251 cells at 100 uM after 4 hrs by FACS in presence of N-acetyl-L-cysteine [AID347397, Type: Literature]
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14
[SID103176198]
Inhibition of 26S proteasome activity in human U251 cells at 0.5 mM after 24 hrs [AID347410, Type: Literature]
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15
[SID103176198]
Pre-emergence herbicidal activity against Lolium rigidum seeds assessed as seed germination at 0.1 mol/l at 25 degC after 72 hr by laboratory-based agar medium bioassay relative to 1,8-Cineole [AID1081607, Type: Literature]
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16
[SID103176198]
Pre-emergence herbicidal activity against Lolium rigidum seeds assessed as shoot length at 0.1 mol/l at 25 degC after 72 hr by laboratory-based agar medium bioassay relative to 1,8-Cineole [AID1081608, Type: Literature]
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17
[SID103176198]
Pre-emergence herbicidal activity against Lolium rigidum seeds assessed as root length at 0.1 mol/l at 25 degC after 72 hr by laboratory-based agar medium bioassay relative to 1,8-Cineole [AID1081609, Type: Literature]
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18
[SID103176198]
Pre-emergence herbicidal activity against Raphanus sativus var.Long scarlet (radish) seeds assessed as seed germination at 0.1 mol/l at 25 degC after 72 hr by laboratory-based agar medium bioassay relative to 1,8-Cineole [AID1081610, Type: Literature]
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19
[SID103176198]
Pre-emergence herbicidal activity against Raphanus sativus var.Long scarlet (radish) seeds assessed as shoot length at 0.1 mol/l at 25 degC after 72 hr by laboratory-based agar medium bioassay relative to 1,8-Cineole [AID1081611, Type: Literature]
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20
[SID103176198]
Pre-emergence herbicidal activity against Raphanus sativus var.Long scarlet (radish) seeds assessed as root length at 0.1 mol/l at 25 degC after 72 hr by laboratory-based agar medium bioassay relative to 1,8-Cineole [AID1081612, Type: Literature]
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