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1-Butanol (CID 263) - Compound BioActivity Data
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BioActivity Outcomes:
Active(4)
 
 
Inactive(529)
 
 
Inconclusive(25)
 
 
Unspecified(18)
 
 
Top Targets:
NR LBD PPAR(20)
 
 
 
NR LBD ER(18)
 
 
NR LBD AR(18)
 
 
 
 
NR LBD TR(14)
 
 
NR LBD GR(12)
 
 
 
BioAssay Types:
Confirmatory(437)
 
 
 
 
Literature(79)
 
 
 
 
Summary(39)
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(394)
 
 
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 283    Data Row: 576   Total Pages: 12   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144207939]
Potency-Replicate_1 48.7925qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway [AID743036, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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2
[SID144204597]
qHTS of D3 Dopamine Receptor Agonist: qHTS [AID652048, Type: screening]D(3) dopamine receptor isoform e [Homo sapiens] [gi:89191863]
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3
[SID144204597]
qHTS of D3 Dopamine Receptor Potentiators: qHTS [AID652051, Type: screening]D(3) dopamine receptor isoform e [Homo sapiens] [gi:89191863]
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4
[SID48414932]
DSSTox (EPAFHM) EPA Fathead Minnow Acute Toxicity [AID1188, Type: other]
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5
[SID103176188]
Km 13000Compound was evaluated for reversible inhibition of hydrolysis acetylcholine by acetylcholinesterase and represented as Km(app) apparent binding constant [AID30253, Type: Literature]
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6
[SID103176188]
Ki 47000Compound was evaluated for reversible inhibition of hydrolysis acetylcholine by acetylcholinesterase and represented as KI(com) [AID30246, Type: Literature]
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7
[SID103176188]
LC50 2.70396e+07Toxicity determined using Golden Orfe Fish Test [AID101345, Type: Literature]
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8
[SID103176188]
Toxicity determined using Microtox Test [AID159270, Type: Literature]
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9
[SID103176188]
Eye irritation potential accessed using Draize in vivo rabbit eye irritation test [AID167125, Type: Literature]
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10
[SID103176188]
Inhibition of Rana pipiens muscle activity. [AID168703, Type: Literature]
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11
[SID103176188]
Toxicity determined using Tadpole Narcosis Test [AID212400, Type: Literature]
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12
[SID103176188]
Lipophilicity determined as logarithm of the partition coefficient in the alkane/water system [AID237685, Type: Literature]
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13
[SID103176188]
Binding affinity to beta cyclodextrin [AID346025, Type: Literature]
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14
[SID17388872]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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15
[SID103176188]
Partition coefficient (logP) [AID23251, Type: Literature]
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16
[SID103176188]
Partition coefficient (logP) (benzene) [AID23252, Type: Literature]
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17
[SID103176188]
Partition coefficient (logP) (carbon tetrachloride) [AID23253, Type: Literature]
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18
[SID103176188]
Partition coefficient (logP) (chloroform) [AID23254, Type: Literature]
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19
[SID103176188]
Partition coefficient (logP) (ether) [AID23255, Type: Literature]
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20
[SID103176188]
Partition coefficient (logP) (hexane) [AID23256, Type: Literature]
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21
[SID17389645]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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22
[SID17388872]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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23
[SID17388872]
Potency 0.3162qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID2517, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
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24
[SID144204597]
Potency-Replicate_1 33.4915qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 - cell viability [AID651634, Type: confirmatory]
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25
[SID17389645]
Potency-Replicate_1 qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway - cell viability counter screen [AID720652, Type: confirmatory]
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26
[SID17389645]
Potency-Replicate_1 qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway measured by Nrf2-dependant transcriptional activity - cell viability counter screen [AID720653, Type: confirmatory]
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27
[SID144204597]
Potency-Replicate_1 qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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28
[SID144204597]
Potency-Replicate_1 qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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29
[SID144204597]
Ratio Potency (uM) qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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30
[SID144204597]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HepG2 cells [AID720674, Type: confirmatory]
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31
[SID144204597]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 535 nm (green) in HepG2 cells [AID720675, Type: confirmatory]
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32
[SID144204597]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HEK293 cells [AID720678, Type: confirmatory]
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33
[SID144204597]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HEK293 cells [AID720679, Type: confirmatory]
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34
[SID144204597]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 535 nm (green) in HEK293 cells [AID720680, Type: confirmatory]
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35
[SID144204597]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HEK293 cell free culture [AID720681, Type: confirmatory]
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36
[SID144204597]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 535 nm (green) in HEK293 cell free culture [AID720682, Type: confirmatory]
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37
[SID144204597]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HEK293 cell free culture [AID720683, Type: confirmatory]
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38
[SID144204597]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HepG2 cell free culture [AID720684, Type: confirmatory]
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39
[SID144204597]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HepG2 cell free culture [AID720685, Type: confirmatory]
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40
[SID144204597]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 535 nm (green) in HepG2 cell free culture [AID720686, Type: confirmatory]
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41
[SID144204597]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HepG2 cells [AID720687, Type: confirmatory]
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42
[SID144204597]
Potency qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID720533, Type: confirmatory]
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43
[SID144204597]
Potency-Replicate_1 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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44
[SID144204597]
Potency-Replicate_1 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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45
[SID144204597]
Potency-Replicate_1 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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46
[SID144204597]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway - cell viability counter screen [AID743033, Type: confirmatory]
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47
[SID144204597]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line - cell viability counter screen [AID743041, Type: confirmatory]
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48
[SID144204597]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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49
[SID144204597]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway - cell viability counter screen [AID743074, Type: confirmatory]
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50
[SID144204597]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway - cell viability counter screen [AID720693, Type: confirmatory]
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