2-(p-Propoxyphenyl)acetohydroxamic acid
(CID
25922
) -
BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(
4
)
Inactive(
1
)
BioAssay Types:
Confirmatory(
5
)
BioActivity Types:
IC50(
4
)
SAR
Target summary
Data download
Chemical Probe
Active
Inactive
Inconclusive
Unspecified
Total Bioassays: 5 Data Row: 5 Total Pages: 1
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#
Substance
Activity
BioAssay
Target
Links
Outcome
Type
Value [μM]
1
[SID
131485162
]
Active
IC50
0.49
Name: Counterscreen for inhibitors of PFM17LAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Human M17LAP (HUM17LAP) [AID
602407
, Type: confirmatory]
View
X
Row No.
1
Structure
Substance
SID
131485162
CID
25922
Outcome
Active
IC50
0.49 [uM]
BioAssay
Name: Counterscreen for inhibitors of PFM17LAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Human M17LAP (HUM17LAP)
AID
602407
BioAssay type
confirmatory
Target
PubMed
Data Table
2
[SID
131485162
]
Active
IC50
1.39
QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (3) [AID
602309
, Type: confirmatory]
View
X
Row No.
2
Structure
Substance
SID
131485162
CID
25922
Outcome
Active
IC50
1.39 [uM]
BioAssay
QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (3)
AID
602309
BioAssay type
confirmatory
Target
PubMed
Data Table
3
[SID
131485162
]
Active
IC50
16.66
Counterscreen for inhibitors of PFM17LAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M1AAP (PFM1AAP) (3) [AID
602315
, Type: confirmatory]
View
X
Row No.
3
Structure
Substance
SID
131485162
CID
25922
Outcome
Active
IC50
16.66 [uM]
BioAssay
Counterscreen for inhibitors of PFM17LAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M1AAP (PFM1AAP) (3)
AID
602315
BioAssay type
confirmatory
Target
PubMed
Data Table
4
[SID
131485162
]
Active
IC50
26.08
Counterscreen for inhibitors of PFM17LAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP) (3) [AID
602316
, Type: confirmatory]
View
X
Row No.
4
Structure
Substance
SID
131485162
CID
25922
Outcome
Active
IC50
26.08 [uM]
BioAssay
Counterscreen for inhibitors of PFM17LAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP) (3)
AID
602316
BioAssay type
confirmatory
Target
PubMed
Data Table
5
[SID
131485162
]
Inactive
CC50
Vero Cytoxicity Assay: A Cell Based Secondary Assay To Explore Cytotoxicity of Compounds that Inhibit Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (3) [AID
602317
, Type: confirmatory]
View
X
Row No.
5
Structure
Substance
SID
131485162
CID
25922
Outcome
Inactive
CC50
[uM]
BioAssay
Vero Cytoxicity Assay: A Cell Based Secondary Assay To Explore Cytotoxicity of Compounds that Inhibit Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (3)
AID
602317
BioAssay type
confirmatory
Target
PubMed
Data Table