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Carisoprodol (CID 2576) - Compound BioActivity Data
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BioActivity Outcomes:
Active(2)
 
 
Inactive(1537)
 
 
Inconclusive(64)
 
 
Unspecified(67)
 
 
Top Targets:
7tm 4(58)
 
 
 
NR LBD PPAR(32)
 
 
 
NR LBD ER(22)
 
 
 
NR LBD TR(20)
 
 
NR LBD AR(18)
 
 
 
BioAssay Types:
Confirmatory(775)
 
 
 
 
 
Screening(608)
 
 
 
 
Literature(141)
 
 
 
Summary(49)
 
 
BioActivity Types:
Potency(697)
 
 
 
 
 
IC50(46)
 
 
EC50(11)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1199    Data Row: 1670   Total Pages: 84   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID90341406]
Potency 0.006qHTS Validation Assay for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails [AID488953, Type: confirmatory]chromobox protein homolog 1 [Homo sapiens] [gi:187960037]
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2
[SID10321151]
MDR-1 [AID377, Type: other]multidrug resistance protein 1 [Homo sapiens] [gi:42741659]
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3
[SID103377629]
Inhibition of human FAAH at 1 uM [AID468443, Type: Literature]Fatty-acid amide hydrolase 1 [gi:60416391]
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4
[SID855912]
Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae_specifically_AGP1 [AID1887, Type: screening]Agp1p [Saccharomyces cerevisiae S288c] [gi:85666113]
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5
[SID8149234]
Screen for compounds that increase glutamate transport activity in MN-1 cell line (GluUPTAKE) [AID1612, Type: other]
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6
[SID8149234]
Screen for compounds that inhibit protein aggregation formed by mutant SOD1 (GFPSOD1) [AID1613, Type: other]
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7
[SID8149234]
Screen for compounds that reduce polyglutamine (polyQ) inclusions in nerve growth factor (NGF)-treated PC12 cells (GFPQ80) [AID1614, Type: other]
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8
[SID8149234]
Yeast cell-based screen for compounds that suppress polyglutamine aggregation in vivo (75Q-TubH) [AID1616, Type: other]
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9
[SID26752303]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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10
[SID104171140]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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11
[SID103377629]
Inhibition of beta-lactamase at 100 uM [AID43581, Type: Literature]
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12
[SID103377629]
Inhibition of chymotrypsin at 250 uM [AID52790, Type: Literature]
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13
[SID103377629]
Inhibition of malate dehydrogenase (MDH) at 400 uM [AID106806, Type: Literature]
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14
[SID103377629]
Lipophilicity, log D at pH7.4 [AID298031, Type: Literature]
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15
[SID103377629]
Lipophilicity, log D at pH 7.4 by liquid chromatography [AID395324, Type: Literature]
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16
[SID103377629]
Lipophilicity, log P by microemulsion electrokinetic chromatography [AID395325, Type: Literature]
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17
[SID8149234]
Assay to identify inhibitors of polyglutamine-induced caspase-3 activation (CASP3) [AID1583, Type: other]
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18
[SID8149234]
Yeast cell-based screen for compounds that suppress polyglutamine aggregation in vivo (75Q-TubU) [AID1593, Type: other]
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19
[SID8149234]
Screen for compounds that selectively inhibit cytochrome c release from purified mitochondria (CytoCRel) [AID1603, Type: other]
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20
[SID8149234]
Screen for compounds that inhibit polyglutamine induced protein aggregation (AGREG) [AID1604, Type: other]
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