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MLS000537059 (CID 25714087) - Compound BioActivity Data
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BioActivity Outcomes:
Active(15)
 
 
Inactive(674)
 
 
Inconclusive(24)
 
 
Unspecified(2)
 
 
Top Targets:
7tm 4(35)
 
 
alkPPc(12)
 
 
Bcl-2 like(11)
 
 
G-alpha(8)
 
 
 
Tryp SPc(7)
 
 
BioAssay Types:
Screening(488)
 
 
 
 
 
Confirmatory(206)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(147)
 
 
 
 
 
IC50(43)
 
 
 
 
EC50(9)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 651    Data Row: 715   Total Pages: 36   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17407052]
Potency 2.2387qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding [AID1460, Type: confirmatory]Microtubule-associated protein tau [Homo sapiens] [gi:92096784]
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2
[SID17407052]
IC50 (with Meropenem) 5.985Screen and Counter Screen to Identify Novel Compounds that Selectively Sensitize Mycobacterium Tuberculosis to Beta-lactam Antibiotics [AID434987, Type: confirmatory]
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3
[SID17407052]
IC90 12.5Screen to Identify Novel Compounds That Sensitize Mycobacterium Tuberculosis to Beta-lactam Antibiotics [AID434955, Type: confirmatory]
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4
[SID17407052]
Potency 14.581qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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5
[SID17407052]
Potency 16.3601A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. [AID624296, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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6
[SID17407052]
Potency 23.1093qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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7
[SID17407052]
IC50 uHTS fluorescence assay for the identification of Human Immunodeficiency Virus Fusion Inhibitors. [AID1986, Type: confirmatory]envelope glycoprotein [Human immunodeficiency virus 1] [gi:45357394]
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8
[SID17407052]
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of tRNA 2'-phosphotransferase (TPT1). [AID1962, Type: screening]likely tRNA 2'-phosphotransferase [Candida albicans SC5314] [gi:68476498]
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9
[SID17407052]
Fluorescence polarization-based biochemical high throughput confirmation assay to identify inhibitors of tRNA 2'-phosphotransferase (TPT1). [AID2149, Type: screening]likely tRNA 2'-phosphotransferase [Candida albicans SC5314] [gi:68476498]
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10
[SID17407052]
High-content cell-based screening for modulators of autophagy [AID463193, Type: screening]microtubule-associated proteins 1A/1B light chain 3A isoform b [Homo sapiens] [gi:31563518]
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11
[SID17407052]
Fluorescence polarization-based counterscreen assay for inhibitors of tRNA 2'-phosphotransferase (TPT1): biochemical high throughput screening assay to identify inhibitors of RNAse T1. [AID2153, Type: screening]unnamed protein product [Aspergillus oryzae RIB40] [gi:83774548]
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12
[SID17407052]
uHTS identification of small molecule activators of the adaptive arm of the Unfolded Protein response via a luminescent-based reporter assay [AID463104, Type: screening]
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13
[SID17407052]
Single concentration confirmation of small molecule activators of the adaptive arm of the Unfolded Protein response via a luminescent-based reporter assay [AID485299, Type: screening]
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14
[SID17407052]
HTS for suppressors of simvastatin-induced mytoxicity in differentiated C2C12 cells Measured in Cell-Based System Using Plate Reader - 2112-01_Suppressor_SinglePoint_HTS_Activity [AID602340, Type: screening]
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15
[SID17407052]
uHTS identification of inhibitors of NadD in a Colorimetric assay [AID602399, Type: screening]hypothetical protein SA1422 [Staphylococcus aureus subsp. aureus N315] [gi:15927174]
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16
[SID17407052]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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17
[SID17407052]
Assay for HTS of Gi/Go-linked GPCRs using mGluR8: Primary Screening [AID488969, Type: screening]metabotropic glutamate receptor 8 [Rattus norvegicus] [gi:1575471]
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18
[SID17407052]
Potency 1.1689Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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19
[SID17407052]
Meropenem IC50 @ Approximate Cmpd IC50 (uM) 4.01Secondary Screen to Confirm Synergistic Effect of Compounds with Meropenem Against Mycobacterium Tuberculosis [AID485340, Type: confirmatory]
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20
[SID17407052]
Potency 4.4668qHTS Assay for Inhibitors of Influenza NS1 Protein Function [AID2326, Type: confirmatory]nonstructural protein 1 [Influenza A virus (A/WSN/1933(H1N1))] [gi:194352380]
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