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Ethionine (CID 25674) - Compound BioActivity Data
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BioActivity Outcomes:
Active(4)
 
 
Inactive(74)
 
 
Inconclusive(3)
 
 
Unspecified(1139)
 
 
Top Targets:
p450(9)
 
 
 
 
HSD10-like SD..(4)
 
 
ampC(2)
 
 
CASc(2)
 
 
Firefly Luc l..(2)
 
 
BioAssay Types:
Confirmatory(61)
 
 
 
 
Literature(6)
 
 
 
 
Screening(3)
 
 
BioActivity Types:
Potency(36)
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1212    Data Row: 1220   Total Pages: 61   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103480611]
Ki 0.1Displacement of [3H]L-leucine from alpha-2delta containing calcium channel in murine brain [AID261154, Type: Literature]Voltage-dependent calcium channel subunit alpha-2/delta-1 [gi:46576352]
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2
[SID48413733]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
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3
[SID48413733]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
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4
[SID4253465]
p450-cyp1a2 [AID410, Type: confirmatory]cytochrome P450 1A2 [Homo sapiens] [gi:73915100]
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5
[SID4253465]
Cytochrome panel assay with activity outcomes [AID1851, Type: other]
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6
[SID103480611]
Literature-mined public compounds from Lowe et al phospholipidosis modelling dataset [AID588208, Type: Literature]
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7
[SID103480611]
Literature-mined public compounds from Greene et al multi-species hepatotoxicity modelling dataset [AID588209, Type: Literature]
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8
[SID103480611]
Human drug-induced liver injury (DILI) modelling dataset from Ekins et al [AID588210, Type: Literature]
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9
[SID103480611]
Drug Induced Liver Injury Prediction System (DILIps) validation dataset; compound DILI positive/negative as observed in Pfizer data [AID625295, Type: Literature]
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10
[SID103480611]
Open TG-GATES: Regimen: Daily Repeat; Time: 8 day; Dose: Low; Route: Gavage | Dataset: Pathology; Tissue: Kidney; Assay: Interstitium, Connective Tissue, Cellular Infiltration; Study_ID: 126/6 [AID781692, Type: other]
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11
[SID103480611]
Open TG-GATES: Regimen: Daily Repeat; Time: 8 day; Dose: Low; Route: Gavage | Dataset: Pathology; Tissue: Liver; Assay: Cellular Infiltration; Study_ID: 126/6 [AID781693, Type: other]
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12
[SID103480611]
Open TG-GATES: Regimen: Daily Repeat; Time: 15 day; Dose: Low; Route: Gavage | Dataset: Pathology; Tissue: Kidney; Assay: Interstitium, Connective Tissue, Cellular Infiltration; Study_ID: 126/7 [AID781694, Type: other]
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13
[SID103480611]
Open TG-GATES: Regimen: Daily Repeat; Time: 15 day; Dose: Low; Route: Gavage | Dataset: Pathology; Tissue: Kidney; Assay: Renal Tubule, Regeneration; Study_ID: 126/7 [AID781695, Type: other]
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14
[SID103480611]
Open TG-GATES: Regimen: Daily Repeat; Time: 15 day; Dose: Low; Route: Gavage | Dataset: Pathology; Tissue: Liver; Assay: Cellular Infiltration; Study_ID: 126/7 [AID781696, Type: other]
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15
[SID103480611]
Open TG-GATES: Regimen: Daily Repeat; Time: 29 day; Dose: Low; Route: Gavage | Dataset: Pathology; Tissue: Kidney; Assay: Interstitium, Connective Tissue, Cellular Infiltration; Study_ID: 126/8 [AID781697, Type: other]
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16
[SID103480611]
Open TG-GATES: Regimen: Daily Repeat; Time: 29 day; Dose: Low; Route: Gavage | Dataset: Pathology; Tissue: Kidney; Assay: Renal Tubule, Regeneration; Study_ID: 126/8 [AID781698, Type: other]
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17
[SID103480611]
Open TG-GATES: Regimen: Daily Repeat; Time: 29 day; Dose: Low; Route: Gavage | Dataset: Pathology; Tissue: Liver; Assay: Cellular Infiltration; Study_ID: 126/8 [AID781699, Type: other]
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18
[SID103480611]
Open TG-GATES: Regimen: Daily Repeat; Time: 29 day; Dose: Low; Route: Gavage | Dataset: Pathology; Tissue: Kidney; Assay: Cellular Infiltration, Lymphocyte; Study_ID: 126/8 [AID781700, Type: other]
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19
[SID103480611]
Open TG-GATES: Regimen: Daily Repeat; Time: 29 day; Dose: Low; Route: Gavage | Dataset: Pathology; Tissue: Kidney; Assay: Pelvic Cavity, Dilatation; Study_ID: 126/8 [AID781701, Type: other]
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20
[SID103480611]
Open TG-GATES: Regimen: Daily Repeat; Time: 29 day; Dose: Low; Route: Gavage | Dataset: Pathology; Tissue: Kidney; Assay: Eosinophilic Body; Study_ID: 126/8 [AID781702, Type: other]
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