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BioActivity Data for Compound Ethionine (CID 25674)

BioActivity Outcomes:
Active(3)
 
 
Inactive(74)
 
 
Inconclusive(3)
 
 
Unspecified(1142)
 
 
Top Targets:
p450(9)
 
 
 
 
HSD10-like SD..(4)
 
 
P53(2)
 
 
NR LBD GR(2)
 
 
HIF-1a CTAD(2)
 
 
BioAssay Types:
Confirmatory(61)
 
 
 
 
Literature(8)
 
 
 
Screening(3)
 
 
BioAssay Categories:
In vivo(1134)
 
 
Biochemical(3)
 
 
Toxicity(1137)
 
 
 
ADME(5)
 
 
 
Cell-based(2)
 
 
BioActivity Types:
Potency(36)
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1214    Data Row: 1222   Total Pages: 62   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID48413733]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
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2
[SID48413733]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
View
3
[SID4253465]
p450-cyp1a2 [AID410, Type: confirmatory]cytochrome P450 1A2 [Homo sapiens] [gi:73915100]
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4
[SID4253465]
Cytochrome panel assay with activity outcomes [AID1851, Type: other]
View
5
[SID103480611]
Ki Displacement of [3H]L-leucine from alpha-2delta containing calcium channel in murine brain [AID261154, Type: Literature]Voltage-dependent calcium channel subunit alpha-2/delta-1 [gi:46576352]
View
6
[SID103480611]
Drug Induced Liver Injury Prediction System (DILIps) validation dataset; compound DILI positive/negative as observed in Pfizer data [AID625295, Type: Literature]
View
7
[SID103480611]
Literature-mined public compounds from Greene et al multi-species hepatotoxicity modelling dataset [AID588209, Type: Literature]
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8
[SID103480611]
Human drug-induced liver injury (DILI) modelling dataset from Ekins et al [AID588210, Type: Literature]
View
9
[SID103480611]
Literature-mined public compounds from Lowe et al phospholipidosis modelling dataset [AID588208, Type: Literature]
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10
[SID103480611]
Open TG-GATES: Regimen: Daily Repeat; Time: 8 day; Dose: Middle; Route: Gavage | Dataset: Pathology; Tissue: Liver; Assay: Necrosis; Study_ID: 126/10 [AID781716, Type: other]
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11
[SID103480611]
Open TG-GATES: Regimen: Daily Repeat; Time: 15 day; Dose: Middle; Route: Gavage | Dataset: Pathology; Tissue: Kidney; Assay: Renal Tubule, Dilatation, Cystic; Study_ID: 126/11 [AID781717, Type: other]
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12
[SID103480611]
Open TG-GATES: Regimen: Daily Repeat; Time: 15 day; Dose: Middle; Route: Gavage | Dataset: Pathology; Tissue: Kidney; Assay: Renal Tubule, Regeneration; Study_ID: 126/11 [AID781718, Type: other]
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13
[SID103480611]
Open TG-GATES: Regimen: Daily Repeat; Time: 8 day; Dose: Middle; Route: Gavage | Dataset: Pathology; Tissue: Liver; Assay: Centrilobular, Cellular Infiltration; Study_ID: 126/10 [AID781715, Type: other]
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14
[SID103480611]
Open TG-GATES: Regimen: Daily Repeat; Time: 8 day; Dose: Middle; Route: Gavage | Dataset: Pathology; Tissue: Liver; Assay: Portal, Change, Eosinophilic; Study_ID: 126/10 [AID781714, Type: other]
View
15
[SID103480611]
Open TG-GATES: Regimen: Daily Repeat; Time: 8 day; Dose: Middle; Route: Gavage | Dataset: Pathology; Tissue: Liver; Assay: Centrilobular, Change, Eosinophilic; Study_ID: 126/10 [AID781713, Type: other]
View
16
[SID103480611]
Open TG-GATES: Regimen: Daily Repeat; Time: 8 day; Dose: Middle; Route: Gavage | Dataset: Pathology; Tissue: Kidney; Assay: Renal Tubule, Dilatation, Cystic; Study_ID: 126/10 [AID781712, Type: other]
View
17
[SID103480611]
Open TG-GATES: Regimen: Daily Repeat; Time: 8 day; Dose: Middle; Route: Gavage | Dataset: Pathology; Tissue: Liver; Assay: Alteration, Cytoplasmic; Study_ID: 126/10 [AID781711, Type: other]
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18
[SID103480611]
Open TG-GATES: Regimen: Daily Repeat; Time: 8 day; Dose: Middle; Route: Gavage | Dataset: Pathology; Tissue: Kidney; Assay: Interstitium, Connective Tissue, Cellular Infiltration; Study_ID: 126/10 [AID781710, Type: other]
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19
[SID103480611]
Open TG-GATES: Regimen: Daily Repeat; Time: 4 day; Dose: Middle; Route: Gavage | Dataset: Pathology; Tissue: Kidney; Assay: Renal Tubule, Regeneration; Study_ID: 126/9 [AID781709, Type: other]
View
20
[SID103480611]
Open TG-GATES: Regimen: Daily Repeat; Time: 4 day; Dose: Middle; Route: Gavage | Dataset: Pathology; Tissue: Liver; Assay: Centrilobular, Change, Eosinophilic; Study_ID: 126/9 [AID781708, Type: other]
View