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Carbofuran (CID 2566) - Compound BioActivity Data
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BioActivity Outcomes:
Active(3)
 
 
Inactive(229)
 
 
Inconclusive(17)
 
 
Unspecified(15)
 
 
Top Targets:
NR LBD PPAR(16)
 
 
 
NR LBD ER(14)
 
 
 
 
NR LBD AR(14)
 
 
 
NR LBD VDR(9)
 
 
 
NR LBD TR(8)
 
 
BioAssay Types:
Confirmatory(192)
 
 
 
 
Summary(48)
 
 
 
Literature(15)
 
 
Screening(4)
 
 
BioActivity Types:
Potency(226)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 173    Data Row: 264   Total Pages: 14   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144210940]
Potency-Replicate_1 24.3365qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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2
[SID144210940]
Potency-Replicate_1 24.3365qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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3
[SID48415349]
DSSTox (EPAFHM) EPA Fathead Minnow Acute Toxicity [AID1188, Type: other]
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4
[SID103223482]
In vitro insecticidal activity in bovine serum against adult stable fly [AID33089, Type: Literature]
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5
[SID103223482]
In vitro insecticidal activity in bovine serum against Blowfly larvae [AID42466, Type: Literature]
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6
[SID103223482]
Binding energy by using the equation deltaG obsd = -RT ln KD [AID227718, Type: Literature]
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7
[SID103223482]
Nematicidal activity against Meloidogyne incognita assessed as larval mortality at 1% drug concentration after 24 hrs [AID380390, Type: Literature]
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8
[SID103223482]
Nematicidal activity against Meloidogyne incognita assessed as larval mortality at 1% drug concentration after 48 hrs [AID380391, Type: Literature]
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9
[SID103223482]
Nematicidal activity against Meloidogyne incognita assessed as larval mortality at 1% drug concentration after 72 hrs [AID380392, Type: Literature]
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10
[SID103223482]
Inhibition of Anopheles gambiae AChE [AID671037, Type: Literature]Acetylcholinesterase [gi:92090582]
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11
[SID103223482]
Inhibition of Anopheles gambiae AChE expressed in Escherichia coli after 6 mins by Ellman assay [AID671039, Type: Literature]Acetylcholinesterase [gi:92090582]
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12
[SID103223482]
Inhibition of human recombinant AChE after 6 mins by Ellman assay [AID671040, Type: Literature]Acetylcholinesterase [gi:113037]
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13
[SID103223482]
Selectivity ratio of Ki for Anopheles gambiae AChE to Ki for human recombinant AChE [AID671041, Type: Literature]
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14
[SID103223482]
Toxicity in Anopheles gambiae G3 assessed as mortality treated as tarsal contact using dried filter papers after 24 hrs [AID671042, Type: Literature]
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15
[SID103223482]
Toxicity in anesthetized Anopheles gambiae G3 assessed as mortality treated as topical application assessed per mosquito after 24 hrs [AID671043, Type: Literature]
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16
[SID103223482]
Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977599, Type: Literature]
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17
[SID103223482]
Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977602, Type: Literature]
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18
[SID103223482]
Inhibition of human FAAH at 1 uM [AID468443, Type: Literature]Fatty-acid amide hydrolase 1 [gi:60416391]
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19
[SID144210940]
Potency-Replicate_1 2.4541qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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20
[SID144210940]
Potency-Replicate_1 54.941qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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