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(2E)-3-(1-benzyl-3-thien-2-yl-1H-pyrazol-4-yl)acrylic acid (CID 2554530) - Compound BioActivity Data
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BioActivity Outcomes:
Active(15)
 
 
Inactive(669)
 
 
Inconclusive(12)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(41)
 
 
 
Bcl-2 like(11)
 
 
alkPPc(10)
 
 
G-alpha(8)
 
 
 
Tryp SPc(7)
 
 
BioAssay Types:
Screening(467)
 
 
 
 
Confirmatory(205)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(143)
 
 
 
 
IC50(39)
 
 
EC50(17)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 631    Data Row: 697   Total Pages: 35   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID24834479]
EC50_MICROM 1.94Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant [AID1339, Type: confirmatory]Rac1 protein [Homo sapiens] [gi:8574038]
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2
[SID24834479]
EC50_MICROM 2.18Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant [AID1333, Type: confirmatory]cell division cycle 42 (GTP binding protein, 25kDa) [Homo sapiens] [gi:56202836]
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3
[SID24834479]
EC50_MICROM 2.283Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype [AID1340, Type: confirmatory]Rac1 protein [Homo sapiens] [gi:8574038]
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4
[SID24834479]
EC50_MICROM 2.353Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab7 wildtype [AID1336, Type: confirmatory]GTP-binding protein (rab7) [Canis lupus familiaris] [gi:164058]
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5
[SID24834479]
EC50_MICROM 3.638Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype [AID1337, Type: confirmatory]Ras-related protein Rab-2A [gi:46577642]
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6
[SID24834479]
EC50_MICROM 3.992Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype [AID1334, Type: confirmatory]cell division cycle 42 (GTP binding protein, 25kDa) [Homo sapiens] [gi:56202836]
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7
[SID24834479]
EC50_MICROM 4.033Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype [AID1335, Type: confirmatory]ras protein, partial [Homo sapiens] [gi:190938]
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8
[SID24834479]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype [AID759, Type: screening]ras protein, partial [Homo sapiens] [gi:190938]
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9
[SID24834479]
Absorbance-based biochemical primary high throughput screening assay to identify activators of Methionine sulfoxide reductase A (MsrA) [AID602163, Type: screening]MSRA protein [Bos taurus] [gi:73586699]
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10
[SID24834479]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype [AID761, Type: screening]cell division cycle 42 (GTP binding protein, 25kDa) [Homo sapiens] [gi:56202836]
View
11
[SID24834479]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype [AID757, Type: screening]Rac1 protein [Homo sapiens] [gi:8574038]
View
12
[SID24834479]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant [AID764, Type: screening]Rac1 protein [Homo sapiens] [gi:8574038]
View
13
[SID24834479]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype [AID760, Type: screening]Ras-related protein Rab-2A [gi:46577642]
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14
[SID24834479]
Aqueous Solubility from MLSMR Stock Solutions [AID1996, Type: other]
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15
[SID24834479]
Primary cell-based high-throughput screening assay for antagonists of NPY-Y1 [AID1040, Type: screening]neuropeptide Y receptor type 1 [Homo sapiens] [gi:4505445]
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16
[SID24834479]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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17
[SID24834479]
Potency 7.9433qHTS for Inhibitors of ATXN expression [AID651635, Type: confirmatory]ataxin-2 [Homo sapiens] [gi:171543895]
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18
[SID24834479]
Potency 89.1251qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
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19
[SID24834479]
uHTS Fluorescent assay for identification of inhibitors of Apaf-1 [AID489030, Type: screening]Apoptotic peptidase activating factor 1 [Homo sapiens] [gi:187952397]
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20
[SID24834479]
uHTS Fluorescent assay for identification of activators of Apaf-1 [AID489031, Type: screening]Apoptotic peptidase activating factor 1 [Homo sapiens] [gi:187952397]
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