Bookmark and Share
Carbachol (CID 2551) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(10)
 
 
Inactive(353)
 
 
Inconclusive(21)
 
 
Unspecified(7)
 
 
Top Targets:
p450(18)
 
 
 
7tm 4(10)
 
 
 
HSD10-like SD..(8)
 
 
GH27(6)
 
 
Neur chan LBD(5)
 
 
 
BioAssay Types:
Confirmatory(282)
 
 
 
 
Literature(77)
 
 
 
 
Screening(1)
 
 
BioActivity Types:
Potency(232)
 
 
 
 
Ki(8)
 
 
 
Kd(2)
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 200    Data Row: 391   Total Pages: 20   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID104234184]
Ki 0.005Binding affinity to muscarinic M1/M5 receptor (unknown origin) [AID781214, Type: Literature]Muscarinic acetylcholine receptor M1 [gi:113118]
View
2
[SID104234184]
Ki 0.005Binding affinity to muscarinic M1/M5 receptor (unknown origin) [AID781214, Type: Literature]Muscarinic acetylcholine receptor M2 [gi:113122]
View
3
[SID104234184]
Ki 0.005Binding affinity to muscarinic M1/M5 receptor (unknown origin) [AID781214, Type: Literature]Muscarinic acetylcholine receptor M3 [gi:113125]
View
4
[SID104234184]
Ki 0.005Binding affinity to muscarinic M1/M5 receptor (unknown origin) [AID781214, Type: Literature]Muscarinic acetylcholine receptor M5 [gi:543761]
View
5
[SID104234184]
Ki 0.005Binding affinity to muscarinic M1/M5 receptor (unknown origin) [AID781214, Type: Literature]Muscarinic acetylcholine receptor M4 [gi:23503039]
View
6
[SID104234184]
Ki 0.75Binding affinity to alpha4beta2 nAChR (unknown origin) [AID781216, Type: Literature]Neuronal acetylcholine receptor subunit beta-2 [gi:113105]
View
7
[SID104234184]
Ki 0.75Binding affinity to alpha4beta2 nAChR (unknown origin) [AID781216, Type: Literature]Neuronal acetylcholine receptor subunit alpha-4 [gi:1351848]
View
8
[SID46393347]
Kd 7.575Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain C, X-Ray Structure Of Acetylcholine Binding Protein (Achbp) In Complex With Carbamylcholine [gi:47169299]
View
9
[SID46393347]
Kd 7.575Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain D, X-Ray Structure Of Acetylcholine Binding Protein (Achbp) In Complex With Carbamylcholine [gi:47169300]
View
10
[SID46393347]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: other]Chain C, X-Ray Structure Of Acetylcholine Binding Protein (Achbp) In Complex With Carbamylcholine [gi:47169299]
View
11
[SID11110943]
Potency 7.9433qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor [AID926, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
View
12
[SID104234184]
Ki 66Binding affinity to alpha7 nAChR (unknown origin) [AID781215, Type: Literature]Neuronal acetylcholine receptor subunit alpha-7 [gi:2506127]
View
13
[SID104234184]
Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977599, Type: Literature]
View
14
[SID104234184]
Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977602, Type: Literature]
View
15
[SID11110943]
Cytochrome panel assay with activity outcomes [AID1851, Type: other]
View
16
[SID11110944]
Cytochrome panel assay with activity outcomes [AID1851, Type: other]
View
17
[SID26756576]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
View
18
[SID11110943]
Potency 0.1qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C19 [AID899, Type: confirmatory]cytochrome P450 2C19 precursor [Homo sapiens] [gi:4503219]
View
19
[SID90341139]
Potency 3.0131qHTS screen for enhancers of Arylsulfatase A (ASA1): LOPAC Validation Assay [AID720538, Type: confirmatory]arylsulfatase A [Homo sapiens] [gi:220983390]
View
20
[SID11110944]
Potency qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E) [AID2147, Type: confirmatory]Chain A, Crystal Structure Of The Human 2-Oxoglutarate Oxygenase Loc390245 [gi:221046486]
View