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7-Amino-6-methoxy-5,8-quinolinedione (CID 253693) - Compound BioActivity Data
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BioActivity Outcomes:
Active(6)
 
 
Inactive(9)
 
 
Inconclusive(1)
 
 
Unspecified(12)
 
 
Top Targets:
PAD(4)
 
 
 
PAD M(2)
 
 
BioAssay Types:
Literature(12)
 
 
Confirmatory(2)
 
 
BioActivity Types:
IC50(1)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 20    Data Row: 28   Total Pages: 2   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID118043673]
Late stage assay provider results from the probe development effort to identify inhibitors of PAD4: colorimetric biochemical substrate assay to identify inhibitors of PADs 1-4 [AID588560, Type: other]
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2
[SID118043673]
Late stage assay provider results from the probe development effort to identify inhibitors of PAD4: colorimetric biochemical substrate assay to identify inhibitors of PADs 1-4 [AID588560_1, Type: other]protein-arginine deiminase type-1 [Homo sapiens] [gi:122056685]
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3
[SID118043673]
Late stage assay provider results from the probe development effort to identify inhibitors of PAD4: colorimetric biochemical substrate assay to identify inhibitors of PADs 1-4 [AID588560_2, Type: other]protein-arginine deiminase type-2 [Homo sapiens] [gi:122939159]
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4
[SID118043673]
Late stage assay provider results from the probe development effort to identify inhibitors of PAD4: colorimetric biochemical substrate assay to identify inhibitors of PADs 1-4 [AID588560_3, Type: other]protein-arginine deiminase type-3 [Homo sapiens] [gi:122939161]
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5
[SID118043673]
Late stage assay provider results from the probe development effort to identify inhibitors of Arginine Deiminase 4 (PAD4): colorimetric biochemical substrate assay to identify inhibitors of PAD4 [AID588559, Type: other]protein-arginine deiminase type-4 [Homo sapiens] [gi:216548487]
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6
[SID118043673]
Late stage assay provider results from the probe development effort to identify inhibitors of PAD4: colorimetric biochemical substrate assay to identify inhibitors of PADs 1-4 [AID588560_4, Type: other]protein-arginine deiminase type-4 [Homo sapiens] [gi:216548487]
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7
[SID103245836]
Cytotoxic activity against mouse melanoma cell culture(B-16) [AID38038, Type: Literature]
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8
[SID103245836]
Cytotoxic activity against human lymphoblastic leukemia cell culture (CCRF-CEM) [AID44017, Type: Literature]
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9
[SID103245836]
Antimicrobial activity was determined against Candida albicans ATCC 10231 [AID44988, Type: Literature]
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10
[SID103245836]
Antimicrobial activity was determined against Escherichia coli ATCC 9637 [AID69959, Type: Literature]
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11
[SID103245836]
Cytotoxic activity against human epidermoid carcinoma of the nasopharynx (9KB) [AID70059, Type: Literature]
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12
[SID103245836]
Antimicrobial activity was determined against Klebsiella pneumoniae ATCC 10031 [AID94298, Type: Literature]
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13
[SID103245836]
Cytotoxic activity against mouse lymphoblastic leukemia cell culture (L-1210) [AID94732, Type: Literature]
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14
[SID103245836]
Antimicrobial activity was determined against Mycobacterium smegmatis ATCC 607 [AID144440, Type: Literature]
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15
[SID103245836]
Cytotoxic activity against P388 mouse leukemia cell culture (9PS(P388)) [AID152574, Type: Literature]
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16
[SID103245836]
Antimicrobial activity was determined against Pseudomonas aeruginosa ATCC 27853 cells [AID164400, Type: Literature]
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17
[SID103245836]
Antimicrobial activity was determined against Salmonella gallinarum ATCC 9184 [AID200512, Type: Literature]
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18
[SID103245836]
Antimicrobial activity was determined against Staphylococcus aureus ATCC 13709 [AID207620, Type: Literature]
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19
[SID118043673]
Average IC50 6.3Late stage assay provider results from the probe development effort to identify inhibitors of Protein Arginine Deiminase 4 (PAD4): colorimetric biochemical substrate assay to assess potency of compound 13 against PAD4 [AID588418, Type: confirmatory]protein-arginine deiminase type-4 [Homo sapiens] [gi:216548487]
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20
[SID118043673]
Late stage assay provider results from the probe development effort to identify inhibitors of Protein Arginine Deiminase 4 (PAD4): fluorescence-based biochemical gel-based competitive Activity-Based Protein Profiling (ABPP) assessment of compound selectivity [AID651628, Type: other]
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