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ST50839348 (CID 25237246) - Compound BioActivity Data
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BioActivity Outcomes:
Active(82)
 
 
Inactive(466)
 
 
Inconclusive(28)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(21)
 
 
 
7TM GPCR Srsx(15)
 
 
 
 
TRP 2(5)
 
 
Bcl-2 like(5)
 
 
 
CAP ED(5)
 
 
BioAssay Types:
Screening(383)
 
 
 
 
Confirmatory(179)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(128)
 
 
 
 
 
IC50(38)
 
 
 
EC50(8)
 
 
 
AC50(3)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 527    Data Row: 577   Total Pages: 29   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID49823586]
Potency 3.6626A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. [AID624296, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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2
[SID49823586]
EC50_Mean 4.02Dose response counterscreen for uHTS small molecule activators of the adaptive arm of the Unfolded Protein Response via a luminescent-based reporter assay [AID489027, Type: confirmatory]
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3
[SID49823586]
IC50 4.94uHTS Homogeneous Terbium Time-Resolved Fluorescence Resonance Energy Transfer (HTRF) Assay [AID2091, Type: confirmatory]Mint1 [Rattus norvegicus] [gi:2625023]
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4
[SID49823586]
IC50 4.94uHTS Homogeneous Terbium Time-Resolved Fluorescence Resonance Energy Transfer (HTRF) Assay [AID2091, Type: confirmatory]voltage-dependent N-type calcium channel subunit alpha-1B isoform 1 [Homo sapiens] [gi:4502523]
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5
[SID49823586]
EC50_Mean 5.37Dose response confirmation of small molecule activators of the apoptotic arm of the Unfolded Protein response via a luminescent-based reporter assay [AID489024, Type: confirmatory]
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6
[SID49823586]
IC50 9.123Fluorescence-based biochemical high throughput screening dose response assay to identify inhibitors of Crimean-Congo Hemorrhagic Fever (CCHF) viral ovarian tumor domain protease (vOTU): Pep-AMC substrate [AID720578, Type: confirmatory]putative polyprotein [Crimean-Congo hemorrhagic fever virus] [gi:76364066]
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7
[SID49823586]
Potency 10qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
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8
[SID49823586]
Potency 10qHTS Assay for Inhibitors of DNA Polymerase Beta [AID485314, Type: confirmatory]DNA polymerase beta [Homo sapiens] [gi:4505931]
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9
[SID49823586]
Potency 10qHTS Assay for Inhibitors of Hepatitis C Virus (HCV) [AID651820, Type: confirmatory]
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10
[SID49823586]
Potency 10qHTS for Inhibitors of Polymerase Eta [AID588591, Type: confirmatory]DNA polymerase eta isoform 1 [Homo sapiens] [gi:5729982]
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11
[SID49823586]
Potency 11.5821qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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12
[SID49823586]
Potency 14.581qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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13
[SID49823586]
IC50 15.2Homogeneous Time-Resolved Fluorescence Resonance Energy Transfer (HTRF) Assay [AID2073, Type: confirmatory]voltage-dependent N-type calcium channel subunit alpha-1B isoform 1 [Homo sapiens] [gi:4502523]
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14
[SID49823586]
IC50 15.2Homogeneous Time-Resolved Fluorescence Resonance Energy Transfer (HTRF) Assay [AID2073, Type: confirmatory]Mint1 [Rattus norvegicus] [gi:2625023]
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15
[SID49823586]
IC50 18Dose response confirmation of uHTS inhibitor hits from NadD in a Colorimetric assay [AID624317, Type: confirmatory]hypothetical protein SA1422 [Staphylococcus aureus subsp. aureus N315] [gi:15927174]
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16
[SID49823586]
Potency 21.1923qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]serine/threonine-protein kinase PLK1 [Homo sapiens] [gi:21359873]
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17
[SID49823586]
Potency 22.3872qHTS for Inhibitors of WRN Helicase [AID651768, Type: confirmatory]WRN [Homo sapiens] [gi:3719421]
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18
[SID49823586]
Potency 25.1189qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia [AID2451, Type: confirmatory]Chain A, Structure Of Giardia Fructose-1,6-biphosphate Aldolase In Complex With Phosphoglycolohydroxamate [gi:122920737]
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19
[SID49823586]
Potency 31.6228qHTS Assay for Inhibitors of JMJD2A-Tudor Domain [AID504339, Type: confirmatory]Chain A, Jmjd2a Tandem Tudor Domains In Complex With A Trimethylated Histone H4-K20 Peptide [gi:162330054]
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20
[SID49823586]
IC50_Mean 37.3Dose response confirmation of uHTS inhibitor hits from NadD in a Colorimetric assay - Set 2 [AID651709, Type: confirmatory]hypothetical protein SA1422 [Staphylococcus aureus subsp. aureus N315] [gi:15927174]
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