adenosine-derived inhibitor, 7 (CID 25195347) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(6)
 
 
Unspecified(1)
 
 
BioAssay Types:
Literature(7)
 
 
 
BioActivity Types:
IC50(2)
 
 
 
Kd(2)
 
 
Ki(1)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 7    Data Row: 7   Total Pages: 1   
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103595016]
Kd 0.87Binding affinity to Grp78 by isothermal titration calorimetric analysis [AID600788, Type: Literature]
View
2
[SID103595016]
Kd 0.99Binding affinity to histidine-tagged Grp78 by surface plasmon resonance analysis [AID600785, Type: Literature]
View
3
[SID103595016]
Ki 4.31Inhibition of HSP70 by fluorescence polarization assay [AID600787, Type: Literature]
View
4
[SID103595016]
IC50 9.1Displacement of fluorescein labeled N6-(6-amino)hexyl-ATP-5-FAM from HSP70 by fluorescence polarization assay [AID393506, Type: Literature]
View
5
[SID103595016]
GI50 26Antiproliferative activity against human HCT116 cells [AID600789, Type: Literature]
View
6
[SID103595016]
GI50 26Cytotoxicity against human HCT116 cells by SRB assay [AID393508, Type: Literature]
View
7
[SID103595016]
IC50 400Binding affinity to HSP90 by fluorescence polarization assay [AID393511, Type: Literature]
View