N,N-naphthaloylhydroxylamine (CID 25164) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(7)
 
 
Inactive(1)
 
 
Top Targets:
PLAT LOX(2)
 
 
Peptidase M17(2)
 
 
M1 APN 1(1)
 
 
PTZ00371(1)
 
 
BioAssay Types:
Confirmatory(5)
 
 
 
Literature(3)
 
 
BioActivity Types:
IC50(7)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 8    Data Row: 8   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID131485169]
IC50 8.38Name: Counterscreen for inhibitors of PFM17LAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Human M17LAP (HUM17LAP) [AID602407, Type: confirmatory]leucine aminopeptidase [Homo sapiens] [gi:4335941]
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2
[SID131485169]
IC50 8.38Name: Counterscreen for inhibitors of PFM17LAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Human M17LAP (HUM17LAP) [AID602407, Type: confirmatory]leucine aminopeptidase [Homo sapiens] [gi:4335941]
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3
[SID103402267]
IC50 14In vitro inhibitory activity against RBL-1 5-LO [AID6809, Type: Literature]
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4
[SID103402267]
IC50 14In vitro inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cells(RBL-1) [AID7184, Type: Literature]Arachidonate 5-lipoxygenase [gi:729945]
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5
[SID103402267]
IC50 14.1254Logarithmic value of inhibitory concentration against 5-lipoxygenase in rat basophilic leukemia cells (RBL-1) [AID7185, Type: Literature]Arachidonate 5-lipoxygenase [gi:729945]
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6
[SID131485169]
IC50 46.34QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (3) [AID602309, Type: confirmatory]M17 leucyl aminopeptidase [Plasmodium falciparum 3D7] [gi:23497510]
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7
[SID131485169]
IC50 46.34QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (3) [AID602309, Type: confirmatory]M17 leucyl aminopeptidase [Plasmodium falciparum 3D7] [gi:23497510]
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8
[SID131485169]
IC50 46.34QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (3) [AID602309, Type: confirmatory]M17 leucyl aminopeptidase [Plasmodium falciparum 3D7] [gi:23497510]
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9
[SID131485169]
CC50 50Vero Cytoxicity Assay: A Cell Based Secondary Assay To Explore Cytotoxicity of Compounds that Inhibit Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (3) [AID602317, Type: confirmatory]
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10
[SID131485169]
IC50 100Counterscreen for inhibitors of PFM17LAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP) (3) [AID602316, Type: confirmatory]M18 aspartyl aminopeptidase [Plasmodium falciparum 3D7] [gi:23505220]
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11
[SID131485169]
IC50 100Counterscreen for inhibitors of PFM17LAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP) (3) [AID602316, Type: confirmatory]M18 aspartyl aminopeptidase [Plasmodium falciparum 3D7] [gi:23505220]
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12
[SID131485169]
IC50 Counterscreen for inhibitors of PFM17LAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M1AAP (PFM1AAP) (3) [AID602315, Type: confirmatory]m1-family aminopeptidase [Plasmodium falciparum 3D7] [gi:23615263]
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13
[SID131485169]
IC50 Counterscreen for inhibitors of PFM17LAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M1AAP (PFM1AAP) (3) [AID602315, Type: confirmatory]m1-family aminopeptidase [Plasmodium falciparum 3D7] [gi:23615263]
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