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MLS002178120 (CID 25161477) - Compound BioActivity Data
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BioActivity Outcomes:
Active(3)
 
 
Inactive(441)
 
 
Inconclusive(2)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(35)
 
 
Esterase lipa..(5)
 
 
ANK(4)
 
 
 
RasGEF(4)
 
 
alkPPc(4)
 
 
BioAssay Types:
Screening(318)
 
 
 
 
Confirmatory(114)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(100)
 
 
 
 
IC50(10)
 
 
AC50(2)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 407    Data Row: 447   Total Pages: 23   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID57257239]
AC50_uM 3.486Luminescence Cell-Free Homogeneous Dose Retest to Confirm Inhibitors of GSK-3 alpha [AID463203, Type: confirmatory]glycogen synthase kinase-3 alpha [Homo sapiens] [gi:49574532]
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2
[SID57257239]
Counterscreen for PME1 inhibitors: fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of lysophospholipase 2 (LYPLA2). [AID2177, Type: screening]lysophospholipase II [Homo sapiens] [gi:4581413]
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3
[SID57257239]
Counterscreen for PME1 inhibitors: fluorescence polarization-based biochemical high throughput confirmation assay to identify inhibitors of lysophospholipase 2 (LYPLA2). [AID2232, Type: screening]lysophospholipase II [Homo sapiens] [gi:4581413]
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4
[SID57257239]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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5
[SID57257239]
Potency 14.7157Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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6
[SID57257239]
AC50_uM 300Luminescence Cell-Free Homogeneous Counter Screen to Identify Inhibitors of ADP-glo [AID463205, Type: confirmatory]
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7
[SID57257239]
Phenotypic HTS multiplex for antifungal efflux pump inhibitors [AID485275, Type: screening]
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8
[SID57257239]
Potency qHTS Assay for Small Molecule Inhibitors of Mitochondrial Division or Activators of Mitochondrial Fusion [AID485298, Type: confirmatory]
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9
[SID57257239]
Inhibitors of Prion Protein 5' UTR mRNA Measured in Cell-Based System Using Plate Reader - 2078-01_Inhibitor_SinglePoint_HTS_Activity [AID488862, Type: screening]
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10
[SID57257239]
IC50 Elucidation of physiology of non-replicating, drug-tolerant Mycobacterium tuberculosis [AID488890, Type: confirmatory]
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11
[SID57257239]
IC50 Primary and Confirmatory Screening for Inhibitors of Bacterial Capsule Biogenesis [AID488966, Type: confirmatory]
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12
[SID57257239]
Potency qHTS Assay to Find Inhibitors of Chronic Active B-Cell Receptor Signaling [AID493014, Type: confirmatory]
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13
[SID57257239]
Potency Nrf2 qHTS screen for inhibitors: counterscreen for cytotoxicity [AID504648, Type: confirmatory]
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14
[SID57257239]
Potency Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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15
[SID57257239]
Small Molecules that selectively kill Giardia lamblia: qHTS [AID540267, Type: screening]
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16
[SID57257239]
MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Activator_SinglePoint_HTS_Activity [AID588334, Type: screening]
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17
[SID57257239]
Counterscreen for inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberculosis: Absorbance-based biochemical high throughput Glycerophosphate Dehydrogenase-Triosephosphate Isomerase (GDH-TPI) full deck assay to identify assay artifacts [AID588335, Type: screening]
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18
[SID57257239]
HTS to Find Inhibitors of Pathogenic Pemphigus Antibodies [AID588358, Type: screening]
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19
[SID57257239]
Cholera Quorum: HTS for inducers of light production in the absence ofautoinducers using BH1578 (luxS deficient, cqsA deficient) Measured in Microorganism System Using Plate Reader - 2132-01_Agonist_SinglePoint_HTS_Activity [AID588436, Type: screening]
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20
[SID57257239]
uHTS identification of small molecule modulators of myocardial damage [AID588492, Type: screening]
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