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BioActivity Data for Compound SR-03000000673 (CID 25110544)

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BioActivity Outcomes:
Probe(1)
 
 
Active(37)
 
 
Inactive(320)
 
 
Inconclusive(27)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(35)
 
 
 
ANK(5)
 
 
 
 
Esterase lipa..(4)
 
 
 
Troponin(4)
 
 
RasGEF(4)
 
 
 
BioAssay Types:
Screening(252)
 
 
 
 
Confirmatory(119)
 
 
 
 
 
Literature(11)
 
 
 
Summary(1)
 
 
BioActivity Types:
Potency(101)
 
 
 
 
 
IC50(11)
 
 
 
AC50(4)
 
 
 
EC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 347    Data Row: 386   Total Pages: 20   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID56432669]
Summary of probe development efforts to identify inhibitors of the p97 ATPase. [AID1794, Type: summary]Valosin-containing protein [Homo sapiens] [gi:111305821]
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2
[SID85146558]
AC50_uM 3.865Dose Response HTS Screen to Identify Cytotoxic Compounds of HMLE_sh_eGFP [AID463074, Type: confirmatory]
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3
[SID85146558]
AC50_uM 4.34DiI Quencher Assay Measured in Biochemical System Using Plate Reader - 2085-08_Inhibitor_Dose_CherryPick_Activity [AID540326, Type: confirmatory]scavenger receptor class B member 1 isoform 1 [Mus musculus] [gi:14389423]
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4
[SID85146558]
AC50_uM 4.982Luminescence Cell-Based Dose Retest to Confirm Inhibitors of Cancer Stem Cells [AID449748, Type: confirmatory]
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5
[SID85146558]
EC50_Mean 9.59Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1 [AID504549, Type: confirmatory]neurotensin receptor type 1 [Homo sapiens] [gi:110611243]
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6
[SID85146558]
Potency 10.3225qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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7
[SID85146558]
Potency 11.2202qHTS Assay for Inhibitors of Hepatitis C Virus (HCV) [AID651820, Type: confirmatory]
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8
[SID85146558]
Potency 11.2202qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: Venus Reporter Primary qHTS [AID720580, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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9
[SID85146558]
Potency 12.9953qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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10
[SID85146558]
Potency 22.3872qHTS for Inhibitors of ATXN expression [AID651635, Type: confirmatory]ataxin-2 [Homo sapiens] [gi:171543895]
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11
[SID85146558]
Potency 23.9341qHTS for antagonists of the Thyroid Stimulation Hormone Receptor: Hit Validation in Primary Screen [AID602292, Type: confirmatory]TSHR protein [Homo sapiens] [gi:118341367]
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12
[SID85146558]
FRET-based cell-based primary high throughput screening assay to identify antagonists of the orexin 1 receptor (OX1R; HCRTR1) [AID485270, Type: screening]orexin receptor type 1 [Homo sapiens] [gi:222080095]
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13
[SID85146558]
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of the plasma platelet activating factor acetylhydrolase (pPAFAH) [AID463082, Type: screening]platelet-activating factor acetylhydrolase precursor [Homo sapiens] [gi:270133071]
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14
[SID85146558]
Fluorescence polarization-based biochemical high throughput confirmation assay for inhibitors of the plasma platelet activating factor acetylhydrolase (pPAFAH; PLA2G7) [AID463230, Type: screening]platelet-activating factor acetylhydrolase precursor [Homo sapiens] [gi:270133071]
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15
[SID85146558]
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of human platelet-activating factor acetylhydrolase 1B, catalytic subunit 3 (PAFAH1B3) [AID492972, Type: screening]platelet-activating factor acetylhydrolase IB subunit gamma [Homo sapiens] [gi:225543099]
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16
[SID85146558]
Image-Based HTS for Selective Agonists for NTR1 [AID493036, Type: screening]neurotensin receptor type 1 [Homo sapiens] [gi:110611243]
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17
[SID85146558]
Luminescence-based cell-based primary high throughput screening assay to identify biased ligands of the melanocortin 4 receptor (MC4R): agonists of MC4R [AID540308, Type: screening]melanocortin receptor 4 [Homo sapiens] [gi:119508433]
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18
[SID85146558]
uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
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19
[SID85146558]
Single concentration confirmation of uHTS for Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID489028, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
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20
[SID85146558]
uHTS identification of small molecule inhibitors of the thioesterase domain of fatty acid synthase via a fluorescence intensity assay [AID602261, Type: screening]fatty acid synthase [Homo sapiens] [gi:41872631]
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