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CHEMBL472178 (CID 25053855) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(1)
 
 
Inactive(4)
 
 
Top Targets:
PTKc EGFR(1)
 
 
BioAssay Types:
Literature(5)
 
 
 
BioActivity Types:
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 5    Data Row: 5   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103587113]
IC50 10.4Antiproliferative activity against human HT29 cells after 24 hrs by MTT assay [AID364140, Type: Literature]
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2
[SID103587113]
Cell cycle arrest in human HT29 cells by accumulation at G0/G1 phase at 1 uM after 24 hrs by flow cytometry [AID364142, Type: Literature]
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3
[SID103587113]
Cell cycle arrest in human HT29 cells by accumulation at S phase at 1 uM after 24 hrs by flow cytometry [AID364143, Type: Literature]
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4
[SID103587113]
Cell cycle arrest in human HT29 cells by accumulation at G2/M phase at 1 uM after 24 hrs by flow cytometry [AID364144, Type: Literature]
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5
[SID103587113]
Binding affinity to EGFR in EGF-stimulated human HT29 cells assessed as granular complex formation at 1 uM after 30 mins by confocal laser scanning microscopy [AID364141, Type: Literature]Epidermal growth factor receptor [gi:2811086]
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