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F2019-2710 (CID 24892694) - Compound BioActivity Data
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BioActivity Outcomes:
Active(17)
 
 
Inactive(476)
 
 
Inconclusive(11)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(25)
 
 
 
TRP 2(24)
 
 
 
7TM GPCR Srsx(15)
 
 
CAP ED(5)
 
 
Troponin(4)
 
 
BioAssay Types:
Screening(366)
 
 
 
 
Confirmatory(125)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(102)
 
 
 
 
 
IC50(13)
 
 
 
EC50(8)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 461    Data Row: 505   Total Pages: 26   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID51090753]
IC50_Mean 4.26Dose response confirmation of uHTS inhibitor hits of the mitochondrial permeability transition pore via an absorbance assay [AID651561, Type: confirmatory]
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2
[SID51090753]
EC50 5.308Confirmation dose response assay for compounds that activate transient receptor potential cation channel C4 (TRPC4) [AID434937, Type: confirmatory]alternatively spliced Trp4 [Mus musculus] [gi:2935630]
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3
[SID51090753]
EC50 5.856Luminescence-based cell-based high throughput dose response assay for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors [AID588407, Type: confirmatory]delta-type opioid receptor [Homo sapiens] [gi:63477962]
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4
[SID51090753]
EC50 5.856Luminescence-based cell-based high throughput dose response assay for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors [AID588407, Type: confirmatory]mu-type opioid receptor isoform MOR-1 [Homo sapiens] [gi:117940060]
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5
[SID51090753]
Potency 16.3601qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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6
[SID51090753]
Potency 44.6684qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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7
[SID51090753]
Luminescence-based cell-based high throughput confirmation assay for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors [AID504904, Type: screening]delta-type opioid receptor [Homo sapiens] [gi:63477962]
View
8
[SID51090753]
Luminescence-based cell-based primary high throughput screening assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors [AID504326, Type: screening]mu-type opioid receptor isoform MOR-1 [Homo sapiens] [gi:117940060]
View
9
[SID51090753]
Luminescence-based cell-based high throughput confirmation assay for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors [AID504904, Type: screening]mu-type opioid receptor isoform MOR-1 [Homo sapiens] [gi:117940060]
View
10
[SID51090753]
High throughput screening of inhibitors of transient receptor potential cation channel C6 (TRPC6) [AID2553, Type: screening]short transient receptor potential channel 6 isoform 1 [Mus musculus] [gi:160333370]
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11
[SID51090753]
uHTS identification of small molecule inhibitors of the mitochondrial permeability transition pore via an absorbance assay [AID602449, Type: screening]
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12
[SID51090753]
Confirmatory screen for identification of compounds that activate transient receptor potential cation channel C4 (TRPC4) [AID2426, Type: screening]alternatively spliced Trp4 [Mus musculus] [gi:2935630]
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13
[SID51090753]
Primary cell-based screen for identification of compounds that activate transient receptor potential cation channel C4 (TRPC4). [AID2237, Type: screening]alternatively spliced Trp4 [Mus musculus] [gi:2935630]
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14
[SID51090753]
Specificity screen against TRPC4 for compounds that modulate transient receptor potential cation channel C6 (TRPC6) [AID488927, Type: screening]alternatively spliced Trp4 [Mus musculus] [gi:2935630]
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15
[SID51090753]
Second specificity screen against TRPC4 for compounds that modulate transient receptor potential cation channel C6 (TRPC6) [AID488928, Type: screening]alternatively spliced Trp4 [Mus musculus] [gi:2935630]
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16
[SID51090753]
qHTS for Inhibitors of Inflammasome Signaling: IL-1-beta AlphaLISA Primary Screen [AID743279, Type: screening]interleukin-1 beta proprotein [Homo sapiens] [gi:10835145]
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17
[SID51090753]
Luminescence-based cell-based primary high throughput screening assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors [AID504326, Type: screening]delta-type opioid receptor [Homo sapiens] [gi:63477962]
View
18
[SID51090753]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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19
[SID51090753]
EC50 33.448Counterscreen for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors: Luminescence-based cell-based high throughput dose response assay to identify agonists of OPRM1 homodimerization [AID588435, Type: confirmatory]mu-type opioid receptor isoform MOR-1 [Homo sapiens] [gi:117940060]
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20
[SID51090753]
IC50_Mean 80Dose response confirmation of uHTS inhibitor hits of the mitochondrial permeability transition pore via a fluorescent based counterscreen assay [AID651564, Type: confirmatory]
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