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Triazole Ligand, 12c (CID 24881464) - Compound BioActivity Data
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BioActivity Outcomes:
Active(15)
 
 
Unspecified(2)
 
 
BioAssay Types:
Literature(17)
 
 
 
BioActivity Types:
IC50(15)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 17    Data Row: 17   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103641007]
IC50 0.0035Inhibition of HDAC6 [AID408885, Type: Literature]
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2
[SID103641007]
IC50 0.012Inhibition of HDAC3 [AID408882, Type: Literature]
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3
[SID103641007]
IC50 0.0557Inhibition of HDAC10 [AID408884, Type: Literature]
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4
[SID103641007]
IC50 0.0705Inhibition of HDAC1 [AID408880, Type: Literature]
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5
[SID103641007]
IC50 0.146Inhibition of HDAC2 [AID408881, Type: Literature]
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6
[SID103641007]
IC50 0.17Antimalarial activity against Plasmodium falciparum TM90C2A by hypoxanthine uptake [AID404451, Type: Literature]
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7
[SID103641007]
IC50 0.35Antimalarial activity against Plasmodium falciparum D6 by hypoxanthine uptake [AID404448, Type: Literature]
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8
[SID103641007]
IC50 0.47Antimalarial activity against Plasmodium falciparum TM91C235 by hypoxanthine uptake [AID404450, Type: Literature]
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9
[SID103641007]
IC50 0.518Inhibition of HDAC8 [AID408883, Type: Literature]
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10
[SID103641007]
IC50 0.62Antimalarial activity against Plasmodium falciparum W2 by hypoxanthine uptake [AID404449, Type: Literature]
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11
[SID103641007]
IC50 8Cytotoxicity against human Mia Paca2 cells after 72 hrs by MTT assay [AID404443, Type: Literature]
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12
[SID103641007]
IC50 8Cytotoxicity against human Panc 04.03 cells after 72 hrs by MTT assay [AID404444, Type: Literature]
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13
[SID103641007]
IC50 10Cytotoxicity against human Hup T3 cells after 72 hrs by MTT assay [AID408889, Type: Literature]
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14
[SID103641007]
IC50 11Cytotoxicity against human SU 86.86 cells after 72 hrs by MTT assay [AID404445, Type: Literature]
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15
[SID103641007]
IC50 13Cytotoxicity against human BxPC3 cells after 72 hrs by MTT assay [AID408888, Type: Literature]
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16
[SID103641007]
Selectivity for HDAC6 over HDAC1 [AID408886, Type: Literature]
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17
[SID103641007]
Selectivity for HDAC10 over HDAC1 [AID408887, Type: Literature]
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