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Triazole Ligand, 10c (CID 24881331) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(48)
 
 
Unspecified(6)
 
 
BioAssay Types:
Literature(54)
 
 
 
BioActivity Types:
IC50(28)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 54    Data Row: 54   Total Pages: 3   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103640930]
IC50 0.0072Inhibition of HDAC3 [AID408882, Type: Literature]
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2
[SID103640930]
IC50 0.0072Inhibition of HDAC3 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrs [AID465151, Type: Literature]
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3
[SID103640930]
IC50 0.0096Inhibition of HDAC6 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrs [AID465154, Type: Literature]
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4
[SID103640930]
IC50 0.0096Inhibition of HDAC6 [AID408885, Type: Literature]
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5
[SID103640930]
IC50 0.017Antimalarial activity against Plasmodium falciparum D6 by hypoxanthine uptake [AID404448, Type: Literature]
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6
[SID103640930]
IC50 0.017Antimalarial activity against Plasmodium falciparum TM90C2A by hypoxanthine uptake [AID404451, Type: Literature]
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7
[SID103640930]
IC50 0.018Inhibition of HDAC1 [AID408880, Type: Literature]
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8
[SID103640930]
IC50 0.018Inhibition of HDAC1 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrs [AID465149, Type: Literature]
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9
[SID103640930]
IC50 0.02Growth inhibition of human MIAPaCa2 cells after 72 hrs by MTS assay [AID465157, Type: Literature]
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10
[SID103640930]
IC50 0.02Cytotoxicity against human Mia Paca2 cells after 72 hrs by MTT assay [AID404443, Type: Literature]
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11
[SID103640930]
IC50 0.0277Inhibition of HDAC10 [AID408884, Type: Literature]
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12
[SID103640930]
IC50 0.0277Inhibition of HDAC10 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrs [AID465153, Type: Literature]
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13
[SID103640930]
IC50 0.032Antimalarial activity against Plasmodium falciparum W2 by hypoxanthine uptake [AID404449, Type: Literature]
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14
[SID103640930]
IC50 0.035Antimalarial activity against Plasmodium falciparum TM91C235 by hypoxanthine uptake [AID404450, Type: Literature]
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15
[SID103640930]
IC50 0.0639Inhibition of HDAC2 [AID408881, Type: Literature]
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16
[SID103640930]
IC50 0.0639Inhibition of HDAC2 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrs [AID465150, Type: Literature]
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17
[SID103640930]
IC50 0.2Growth inhibition of human HUPT3 cells after 72 hrs by MTS assay [AID465156, Type: Literature]
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18
[SID103640930]
IC50 0.2Cytotoxicity against human HPDE6c7 cells [AID404447, Type: Literature]
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19
[SID103640930]
IC50 0.2Cytotoxicity against human Hup T3 cells after 72 hrs by MTT assay [AID408889, Type: Literature]
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20
[SID103640930]
IC50 0.4Cytotoxicity against human BxPC3 cells after 72 hrs by MTT assay [AID408888, Type: Literature]
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