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NCGC00162141-01 (CID 24867847) - Compound BioActivity Data
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BioActivity Outcomes:
Active(5)
 
 
Inactive(52)
 
 
Inconclusive(11)
 
 
Top Targets:
7TM GPCR Srx(4)
 
 
 
PIKKc TOR(4)
 
 
Pyr redox dim(4)
 
 
Hexokinase 2(3)
 
 
SIS(3)
 
 
BioAssay Types:
Confirmatory(65)
 
 
 
 
Literature(3)
 
 
BioActivity Types:
Potency(66)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 62    Data Row: 68   Total Pages: 4   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID90340832]
Potency 0.5623HTS Assay for Allosteric Agonists of the Human D1 Dopamine Receptor: Primary Screen for Agonists [AID488981, Type: confirmatory]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
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2
[SID90340832]
Potency 2.9935Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS [AID504845, Type: confirmatory]regulator of G-protein signaling 4 [Homo sapiens] [gi:86301163]
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3
[SID90340832]
Potency 7.3078qHTS of alpha-syn Inhibitors [AID652106, Type: confirmatory]Alpha-synuclein [gi:586067]
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4
[SID90340832]
Potency 8.1995qHTS for compounds that reverse cellular toxicity of Amyloid beta (A-beta) peptide in yeast: LOPAC Validation Assay [AID720559, Type: confirmatory]Amyloid beta A4 protein [gi:112927]
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5
[SID90340832]
Potency 25.1189qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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6
[SID90340832]
Potency 15.8489qHTS for Inhibitors of ATXN expression: Validation [AID588378, Type: confirmatory]ataxin-2 [Homo sapiens] [gi:171543895]
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7
[SID90340832]
Potency 25.1189qHTS Validation Assay for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails [AID488953, Type: confirmatory]chromobox protein homolog 1 [Homo sapiens] [gi:187960037]
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8
[SID90340832]
Potency 29.0929Nrf2 qHTS screen for inhibitors: Validation [AID493153, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 2 [Homo sapiens] [gi:224028257]
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9
[SID90340832]
Potency 29.0929Nrf2 qHTS screen for inhibitors: Validation [AID493153, Type: confirmatory] [geneid:4780]
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10
[SID90340832]
Potency qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
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11
[SID90340832]
Potency qHTS for Inhibitors of ATXN expression: Validation of Cytotoxic Assay [AID588349, Type: confirmatory]
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12
[SID90340832]
Potency qHTS Assay for Identifying Gametocytocidal Compounds [AID743244, Type: confirmatory]
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13
[SID90340832]
Potency qHTS of Nrf2 Activators: LOPAC Validation [AID624149, Type: confirmatory]Nrf2 [Homo sapiens] [gi:693842]
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14
[SID90340832]
Potency qHTS for Activators of Parkin Expression: LOPAC Validation Assay (NLuc Reporter) [AID720572, Type: confirmatory]Parkin [Homo sapiens] [gi:3063388]
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15
[SID90340832]
Potency qHTS for Activators of Parkin Expression: LOPAC Validation Assay (FLuc Reporter) [AID720573, Type: confirmatory]Parkin [Homo sapiens] [gi:3063388]
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16
[SID90340832]
Potency qHTS validation assay of beta-arrestin-biased ligands of beta2-adrenergic receptor [AID485366, Type: confirmatory]beta-2 adrenergic receptor [Homo sapiens] [gi:4501969]
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17
[SID90340832]
Potency qHTS assay for inhibitors of recombinant human GCK-GKRP interaction: Diaphorase-coupled assay [AID743205, Type: confirmatory]glucokinase isoform 1 [Homo sapiens] [gi:4503951]
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18
[SID90340832]
Potency qHTS assay for inhibitors of recombinant human GCK-GKRP interaction: ADP-Glo assay [AID743206, Type: confirmatory]glucokinase isoform 1 [Homo sapiens] [gi:4503951]
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19
[SID90340832]
Potency qHTS assay for inhibitors of recombinant human GCK-GKRP interaction: HTRF assay [AID743207, Type: confirmatory]glucokinase isoform 1 [Homo sapiens] [gi:4503951]
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20
[SID90340832]
Potency qHTS Validation Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1) [AID488816, Type: confirmatory]flap endonuclease 1 [Homo sapiens] [gi:4758356]
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