NCGC00094287-01 (CID 24867527) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Inactive(62)
 
 
Inconclusive(7)
 
 
Unspecified(1)
 
 
Top Targets:
HELICc(4)
 
 
 
NR LBD TR(2)
 
 
Menin(2)
 
 
PLN02808(2)
 
 
Geminin(2)
 
 
BioAssay Types:
Confirmatory(67)
 
 
 
 
Screening(1)
 
 
Literature(1)
 
 
Summary(1)
 
 
BioActivity Types:
Potency(67)
 
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 70    Data Row: 70   Total Pages: 2   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID50106878]
Potency qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding [AID2675, Type: confirmatory]muscleblind-like protein 1 isoform a [Homo sapiens] [gi:41281591]
View
2
[SID50106878]
Potency qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide [AID1766, Type: confirmatory]MEN1 gene product [Homo sapiens] [gi:18860839]
View
3
[SID50106878]
Potency qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide [AID1768, Type: confirmatory]MEN1 gene product [Homo sapiens] [gi:18860839]
View
4
[SID50106878]
Potency qHTS Fluorescence Polarization Assay for Inhibitors of MLL CXXC domain - DNA interaction [AID2662, Type: confirmatory]MLL gene product [Homo sapiens] [gi:56550039]
View
5
[SID50106878]
Potency qHTS Assay for Modulators of Human Peripheral Myelin Protein 22 (PMP22) Expression/Activity [AID1967, Type: confirmatory]peripheral myelin protein 22 [Homo sapiens] [gi:4505907]
View
6
[SID50106878]
Potency qHTS Assay for Inhibitors of DNA Polymerase Beta [AID485314, Type: confirmatory]DNA polymerase beta [Homo sapiens] [gi:4505931]
View
7
[SID50106878]
Potency qHTS Assay for Inhibitors of DNA Polymerase Beta [AID485314, Type: confirmatory]DNA polymerase beta [Homo sapiens] [gi:4505931]
View
8
[SID50106878]
Potency qHTS for Inhibitors of Polymerase Eta [AID588591, Type: confirmatory]DNA polymerase eta [Homo sapiens] [gi:5729982]
View
9
[SID50106878]
Potency qHTS for Inhibitors of Polymerase Eta [AID588591, Type: confirmatory]DNA polymerase eta [Homo sapiens] [gi:5729982]
View
10
[SID50106878]
Potency qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay; Stimulation with EGF [AID1454, Type: confirmatory]mitogen-activated protein kinase 1 [Homo sapiens] [gi:66932916]
View
11
[SID50106878]
Potency qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay; Stimulation with EGF [AID1454, Type: confirmatory]mitogen-activated protein kinase 1 [Homo sapiens] [gi:66932916]
View
12
[SID50106878]
Potency qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay; Stimulation with EGF [AID1454, Type: confirmatory]mitogen-activated protein kinase 1 [Homo sapiens] [gi:66932916]
View
13
[SID50106878]
 qHTS Assay for Inhibitors of RGS12 GoLoco Motif Activity (Red Fluorophore) [AID880, Type: confirmatory]RGS12 [Homo sapiens] [gi:3290016]
View
14
[SID50106878]
Potency qHTS Assay for Enhancers of SMN2 Splice Variant Expression [AID1458, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:10937869]
View
15
[SID50106878]
Potency qHTS Assay for Enhancers of SMN2 Splice Variant Expression [AID1458, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:10937869]
View
16
[SID50106878]
Potency qHTS for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1469, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
View
17
[SID50106878]
Potency qHTS for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1469, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
View
18
[SID50106878]
Potency qHTS for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1469, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
View
19
[SID50106878]
Potency Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1479, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
View
20
[SID50106878]
Potency Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1479, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
View
21
[SID50106878]
Potency Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1479, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
View
22
[SID50106878]
 qHTS for Small Molecule Agonists and Allosteric Enhancers of Human TRH Receptor: Validation Screen for Agonists [AID493127, Type: screening]thyrotropin-releasing hormone receptor [Homo sapiens] [gi:4507681]
View
23
[SID50106878]
Potency Antagonists of the Thyroid Stimulating Hormone Receptor: Validation [AID504821, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
View
24
[SID50106878]
Potency Antagonists of the Thyroid Stimulating Hormone Receptor: Validation [AID504821, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
View
25
[SID50106878]
Potency Antagonists of the Thyroid Stimulating Hormone Receptor: Validation [AID504821, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
View
26
[SID50106878]
Potency qHTS Assay for Antagonists of the Thyroid Stimulating Hormone Receptor [AID488980, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
View
27
[SID50106878]
Potency qHTS Assay for Antagonists of the Thyroid Stimulating Hormone Receptor [AID488980, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
View
28
[SID50106878]
Potency qHTS Assay for Antagonists of the Thyroid Stimulating Hormone Receptor [AID488980, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
View
29
[SID50106878]
Potency HTS Assay for Compounds that Act as Enhancers of the Vanilloid Receptor 1 [AID488979, Type: confirmatory]TRPV1 gene product [Homo sapiens] [gi:74315350]
View
30
[SID50106878]
Potency HTS Assay for Compounds that Act as Enhancers of the Vanilloid Receptor 1 [AID488979, Type: confirmatory]TRPV1 gene product [Homo sapiens] [gi:74315350]
View
31
[SID50106878]
Potency qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
View
32
[SID50106878]
Potency qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
View
33
[SID50106878]
Potency Validation screen for small molecules that induce DNA re-replication in MCF 10A normal breast cells [AID463097, Type: confirmatory]GMNN gene product [Homo sapiens] [gi:7705682]
View
34
[SID50106878]
Potency Validation screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells [AID504364, Type: confirmatory]GMNN gene product [Homo sapiens] [gi:7705682]
View
35
[SID50106878]
Potency qHTS Validation Assay for Inhibitors for MPP8 Chromodomain Interactions with Methylated Histone Tails [AID488949, Type: confirmatory]MPHOSPH8 gene product [Homo sapiens] [gi:41055989]
View
36
[SID50106878]
Potency qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS [AID588453, Type: confirmatory]thioredoxin reductase [Rattus norvegicus] [gi:8659577]
View
37
[SID50106878]
Potency qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS [AID588453, Type: confirmatory]thioredoxin reductase [Rattus norvegicus] [gi:8659577]
View
38
[SID50106878]
Potency qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors: Potentiation with Lithium [AID1457, Type: confirmatory]Inositol monophosphatase [gi:44888968]
View
39
[SID50106878]
Potency qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors: Potentiation with Lithium [AID1457, Type: confirmatory]Inositol monophosphatase [gi:44888968]
View
40
[SID50106878]
Potency qHTS Assay for Antagonists of the Neuropeptide S Receptor: cAMP Signal Transduction [AID1461, Type: confirmatory]NPSR1 gene product [Homo sapiens] [gi:46395496]
View
41
[SID50106878]
Potency qHTS Assay for Antagonists of the Neuropeptide S Receptor: cAMP Signal Transduction [AID1461, Type: confirmatory]NPSR1 gene product [Homo sapiens] [gi:46395496]
View
42
[SID50106878]
Potency qHTS for differential inhibitors of proliferation of Plasmodium falciparum line HB3 [AID1886, Type: confirmatory]
View
43
[SID50106878]
Potency qHTS Assay for Compounds that Induce Erasure of Genomic Imprints [AID1948, Type: confirmatory]
View
44
[SID50106878]
Potency Counterscreen for APE1 Inhibitors: Fluorescent Dye Displacement Validation Assay [AID1707, Type: confirmatory]
View
45
[SID50106878]
Potency Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID488745, Type: confirmatory]
View
46
[SID50106878]
Potency Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID488752, Type: confirmatory]
View
47
[SID50106878]
Potency qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
View
48
[SID50106878]
Potency Validation screen for inhibitors of Lassa infection [AID463096, Type: confirmatory]
View
49
[SID50106878]
Potency Counterscreen for APE1 Inhibitors: qHTS Validation Assay for Inhibitors of Endonuclease IV [AID1708, Type: confirmatory]endonuclease IV [Escherichia coli] [gi:405898]
View
50
[SID50106878]
Potency qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [gi:420597]
View