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BioActivity Data for Compound 2-Chloroadenosine triphosphate tetrasodium (CID 24867489)

BioActivity Outcomes:
Inactive(61)
 
 
Inconclusive(12)
 
 
Unspecified(1)
 
 
Top Targets:
HELICc(4)
 
 
 
Bromo ALL-1(3)
 
 
Tubulin-bindi..(2)
 
 
Peptidase C1A(2)
 
 
NR LBD TR(2)
 
 
BioAssay Types:
Confirmatory(70)
 
 
 
 
Literature(2)
 
 
Screening(1)
 
 
Summary(1)
 
 
BioActivity Types:
Potency(70)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 70    Data Row: 74   Total Pages: 4   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID50106116]
Potency qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding [AID2675, Type: confirmatory]muscleblind-like protein 1 isoform a [Homo sapiens] [gi:41281591]
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2
[SID50106116]
Potency 0.0224qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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3
[SID50106116]
Potency qHTS for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1469, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
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4
[SID50106116]
Potency Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1479, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
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5
[SID50106116]
Potency qHTS Assay for Inhibitors of Influenza NS1 Protein Function [AID2326, Type: confirmatory]nonstructural protein 1 [Influenza A virus (A/WSN/1933(H1N1))] [gi:194352380]
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6
[SID50106116]
Potency qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E) [AID2147, Type: confirmatory]Chain A, Crystal Structure Of The Human 2-Oxoglutarate Oxygenase Loc390245 [gi:221046486]
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7
[SID50106116]
Potency qHTS Validation Assay for Identification of Novel General Anesthetics [AID2323, Type: confirmatory]Chain A, Horse Spleen Apoferritin [gi:254220970]
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8
[SID50106116]
Potency qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent) [AID1478, Type: confirmatory]Chain A, Crystal Structure Of Cruzain Covalently Bound To A Purine Nitrile [gi:281307097]
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9
[SID50106116]
Potency qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent) [AID1476, Type: confirmatory]Chain A, Crystal Structure Of Cruzain Covalently Bound To A Purine Nitrile [gi:281307097]
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10
[SID50106116]
Potency qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1) [AID2549, Type: confirmatory]Chain A, Structure Of Human Recq-Like Helicase In Complex With A Dna Substrate [gi:282403581]
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11
[SID50106116]
Potency qHTS Validation Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1) [AID2353, Type: confirmatory]Chain A, Structure Of Human Recq-Like Helicase In Complex With A Dna Substrate [gi:282403581]
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12
[SID50106116]
Potency qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity [AID588834, Type: Literature]potassium voltage-gated channel subfamily H member 2 isoform d [Homo sapiens] [gi:325651834]
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13
[SID50106116]
Potency qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity [AID588834, Type: Literature]potassium voltage-gated channel subfamily H member 2 isoform d [Homo sapiens] [gi:325651834]
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14
[SID50106116]
Potency qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors: Potentiation with Lithium [AID1457, Type: confirmatory]Inositol monophosphatase 1 [gi:44888968]
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15
[SID50106116]
Potency qHTS for differential inhibitors of proliferation of Plasmodium falciparum line 7G8 [AID1815, Type: confirmatory]
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16
[SID50106116]
Potency qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS [AID588453, Type: confirmatory]thioredoxin reductase [Rattus norvegicus] [gi:8659577]
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17
[SID50106116]
Potency qHTS Assay for Enhancers of SMN2 Splice Variant Expression [AID1458, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:10937869]
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18
[SID50106116]
Potency qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide [AID1766, Type: confirmatory]menin isoform 1 [Homo sapiens] [gi:18860839]
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19
[SID50106116]
Potency qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide [AID1768, Type: confirmatory]menin isoform 1 [Homo sapiens] [gi:18860839]
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20
[SID50106116]
Potency qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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