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BioActivity Data for Compound CGS-21680 hydrochloride (CID 24867487)

BioActivity Outcomes:
Inactive(64)
 
 
Inconclusive(9)
 
 
Unspecified(1)
 
 
Top Targets:
HELICc(4)
 
 
 
Bromo ALL-1(3)
 
 
Tubulin-bindi..(2)
 
 
Peptidase C1A(2)
 
 
NR LBD TR(2)
 
 
BioAssay Types:
Confirmatory(70)
 
 
 
 
Literature(2)
 
 
Screening(1)
 
 
Summary(1)
 
 
BioActivity Types:
Potency(70)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 70    Data Row: 74   Total Pages: 4   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID50106084]
Potency qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding [AID2675, Type: confirmatory]muscleblind-like protein 1 isoform a [Homo sapiens] [gi:41281591]
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2
[SID50106084]
Potency 0.0708qHTS Fluorescence Polarization Assay for Inhibitors of MLL CXXC domain - DNA interaction [AID2662, Type: confirmatory]histone-lysine N-methyltransferase 2A isoform 2 precursor [Homo sapiens] [gi:56550039]
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3
[SID50106084]
Potency 50.1187qHTS Validation Assay for Inhibitors for MPP8 Chromodomain Interactions with Methylated Histone Tails [AID488949, Type: confirmatory]M-phase phosphoprotein 8 [Homo sapiens] [gi:41055989]
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4
[SID50106084]
Potency HTS Assay for Compounds that Act as Enhancers of the Vanilloid Receptor 1 [AID488979, Type: confirmatory]transient receptor potential cation channel subfamily V member 1 [Homo sapiens] [gi:74315350]
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5
[SID50106084]
Potency qHTS Assay for Antagonists of the Thyroid Stimulating Hormone Receptor [AID488980, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
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6
[SID50106084]
qHTS for Small Molecule Agonists and Allosteric Enhancers of Human TRH Receptor: Validation Screen for Agonists [AID493127, Type: screening]thyrotropin-releasing hormone receptor [Homo sapiens] [gi:4507681]
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7
[SID50106084]
Potency qHTS Validation Assay for Inhibitors of Human Galactokinase (GALK) [AID493189, Type: confirmatory]galactokinase [Homo sapiens] [gi:4503895]
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8
[SID50106084]
Potency Validation screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells [AID504364, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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9
[SID50106084]
Potency Antagonists of the Thyroid Stimulating Hormone Receptor: Validation [AID504821, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
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10
[SID50106084]
Potency qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
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11
[SID50106084]
Potency qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1) [AID2549, Type: confirmatory]Chain A, Structure Of Human Recq-Like Helicase In Complex With A Dna Substrate [gi:282403581]
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12
[SID50106084]
Potency qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia [AID2451, Type: confirmatory]Chain A, Structure Of Giardia Fructose-1,6-biphosphate Aldolase In Complex With Phosphoglycolohydroxamate [gi:122920737]
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13
[SID50106084]
Potency qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID2517, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
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14
[SID50106084]
Potency Validation screen for inhibitors of Lassa infection [AID463096, Type: confirmatory]
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15
[SID50106084]
Potency Validation screen for small molecules that induce DNA re-replication in MCF 10A normal breast cells [AID463097, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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16
[SID50106084]
Potency qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1) [AID485290, Type: confirmatory]Chain A, Crystal Structure Of Human Tyrosyl-Dna Phosphodiesterase (Tdp1) [gi:20150581]
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17
[SID50106084]
Potency qHTS Assay for Inhibitors of DNA Polymerase Beta [AID485314, Type: confirmatory]DNA polymerase beta [Homo sapiens] [gi:4505931]
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18
[SID50106084]
Potency Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID488745, Type: confirmatory]
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19
[SID50106084]
Potency Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID488752, Type: confirmatory]
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20
[SID50106084]
Potency qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS [AID588453, Type: confirmatory]thioredoxin reductase [Rattus norvegicus] [gi:8659577]
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