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BioActivity Data for Compound MLS001074450 (CID 24820079)

BioActivity Outcomes:
Active(67)
 
 
Inactive(496)
 
 
Inconclusive(21)
 
 
Unspecified(15)
 
 
Top Targets:
7tm 4(33)
 
 
TNFRSF10(12)
 
 
 
 
KCNQ channel(9)
 
 
 
PP1c bdg(6)
 
 
 
 
Esterase lipa..(5)
 
 
BioAssay Types:
Screening(398)
 
 
 
 
 
Confirmatory(183)
 
 
 
 
 
Literature(11)
 
 
BioAssay Categories:
In vivo(1)
 
 
Biochemical(115)
 
 
Toxicity(11)
 
 
 
Cell-based(129)
 
 
 
 
Organism-base..(13)
 
 
 
BioActivity Types:
Potency(119)
 
 
 
 
 
IC50(46)
 
 
 
 
EC50(8)
 
 
 
AC50(4)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 527    Data Row: 599   Total Pages: 30   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID49829149]
EC50 4.13A cytotoxicity screen of small molecule inhibitors of the PhoP regulon in Salmonella typhimurium identified in the primary screen [AID2253, Type: confirmatory]
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2
[SID49829149]
CC50 5.991A Cell Based Secondary Assay to Explore Cytotoxicity in HepG2 Cells of Compounds that Modulate Non-Replicating, Drug-tolerant Mycobacterium tuberculosis [AID489018, Type: confirmatory]
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3
[SID49829149]
CC50 6.707A Cell Based Secondary Assay To Explore Cytotoxicity of Compounds that Inhibit Mycobacterium Tuberculosis [AID435019, Type: confirmatory]
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4
[SID49829149]
CC50 6.819A Cell Based Secondary Assay to Explore Cytotoxicity in THP-1 Cells of Compounds that Modulate Non-Replicating, Drug-tolerant Mycobacterium tuberculosis [AID489025, Type: confirmatory]
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5
[SID49829149]
EC50 7A cytotoxicity screen of small molecule inhibitors of the PhoP regulon in Salmonella typhi identified in the primary screen [AID2252, Type: confirmatory]
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6
[SID49829149]
IC50 7.511Counterscreen for activators of insulin-degrading enzyme (IDE): fluorescence-based cell-based high throughput dose response LDH release assay to identify compounds that are cytotoxic to HEK cells or compromise cell membrane permeability [AID588440, Type: confirmatory]
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7
[SID49829149]
Potency 11.2202qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: Venus Reporter Primary qHTS [AID720580, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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8
[SID49829149]
AC50_uM 11.65Schnurri-3 Inhibitors: specific inducers of adult bone formation Measured in Cell-Based System Using Plate Reader - 2134-01_Inhibitor_Dose_CherryPick_Activity [AID624132, Type: confirmatory]
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9
[SID49829149]
AC50_uM 11.65Schnurri-3 Inhibitors: specific inducers of adult bone formation Measured in Cell-Based System Using Plate Reader - 2134-01_Inhibitor_Dose_DryPowder_Activity_Set2 [AID743417, Type: confirmatory]
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10
[SID49829149]
Potency 11.6891Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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11
[SID49829149]
Potency 12.9953qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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12
[SID49829149]
AC50_uM 14.06Shn3: Cytotox assay Measured in Cell-Based System Using Plate Reader - 2134-03_Inhibitor_Dose_CherryPick_Activity [AID624134, Type: confirmatory]
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13
[SID49829149]
CC50 15.15A Cell Based Secondary Assay to Explore Cytotoxicity in Vero E6 Cells of Compounds that Modulate Non-Replicating, Drug-tolerant Mycobacterium tuberculosis [AID492998, Type: confirmatory]
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14
[SID49829149]
Potency 16.3601qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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15
[SID49829149]
AC50_uM 16.51Shn3: Dual-Go Shn3RL cells Measured in Cell-Based System Using Plate Reader - 2134-02_Inhibitor_Dose_CherryPick_Activity [AID624133, Type: confirmatory]
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16
[SID49829149]
IC50 17.2A Cell Based Secondary Assay to Explore Compounds that Modulate Non-Replicating, Drug-tolerant Compounds in Replicating H37Rv TB of Mycobacterium tuberculosis [AID492952, Type: confirmatory]
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17
[SID49829149]
Potency 25.1189qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins [AID485364, Type: confirmatory]thioredoxin glutathione reductase [Schistosoma mansoni] [gi:15149312]
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18
[SID49829149]
Potency 31.6228qHTS for Inhibitors of ATXN expression [AID651635, Type: confirmatory]ataxin-2 [Homo sapiens] [gi:171543895]
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19
[SID49829149]
IC50 37.73A Counter Screen to identiry small molecule screen for inhibitors of the PhoP regulon in Salmonella Typhimurium [AID2401, Type: confirmatory]
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20
[SID49829149]
IC50 39.8A counter screen for small molecule screen for inhibitors of the PhoP regulon in Salmonella typhi [AID2384, Type: confirmatory]
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