Bookmark and Share
SMR000622437 (CID 24819152) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(21)
 
 
Inactive(505)
 
 
Inconclusive(18)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(21)
 
 
7TM GPCR Srsx(15)
 
 
CAP ED(5)
 
 
TRP 2(5)
 
 
SLC5sbd CHT(5)
 
 
 
BioAssay Types:
Screening(368)
 
 
 
 
Confirmatory(160)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(116)
 
 
 
 
 
IC50(34)
 
 
 
 
EC50(5)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 498    Data Row: 545   Total Pages: 28   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID87544714]
IC50_Mean 6.51SAR analysis of compounds that inhibit Human Immunodeficiency Virus Fusion. [AID434967, Type: confirmatory]envelope glycoprotein [Human immunodeficiency virus 1] [gi:45357394]
View
2
[SID87544714]
IC50 8SAR analysis of compounds that inhibit Human Immunodeficiency Virus Fusion, cell-cell fusion assay [AID435029, Type: confirmatory]envelope glycoprotein [Human immunodeficiency virus 1] [gi:45357394]
View
3
[SID49826111]
Potency 10.2412qHTS Assay for Inhibitors of GCN5L2: Hit confirmation [AID588347, Type: confirmatory]histone acetyltransferase KAT2A [Homo sapiens] [gi:153791535]
View
4
[SID49826111]
IC50 13.8038Dose responses of compounds that inhibit the Choline Transporter (CHT) - 5 point CRC [AID504840, Type: confirmatory]high affinity choline transporter 1 [Homo sapiens] [gi:11141885]
View
5
[SID49826111]
IC50 16.9uHTS fluorescence assay for the identification of Human Immunodeficiency Virus Fusion Inhibitors. [AID1986, Type: confirmatory]envelope glycoprotein [Human immunodeficiency virus 1] [gi:45357394]
View
6
[SID49826111]
Potency 21.1923qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]serine/threonine-protein kinase PLK1 [Homo sapiens] [gi:21359873]
View
7
[SID49826111]
Potency 28.1838qHTS for Inhibitors of Polymerase Eta [AID588591, Type: confirmatory]DNA polymerase eta [Homo sapiens] [gi:5729982]
View
8
[SID49826111]
Potency 29.8247Confirmation Assay for Inhibitors of Human Galactokinase (GALK) [AID2015, Type: confirmatory]galactokinase [Homo sapiens] [gi:4503895]
View
9
[SID49826111]
Magi EC50 50A Cell Based Assay for the Identification of Lead Compounds with Inhibitory Activity against HIV-1 Fusion (CCR5 Tropic HIV-1 Fusion Inhibition Assay) - Cytotoxicity Counter Screen - Dose Response [AID2286, Type: confirmatory]
View
10
[SID49826111]
Potency 67.4555qHTS for Inhibitors of Polymerase Eta: Confirmatory Assay for Cherry-picked Compounds [AID720502, Type: confirmatory]DNA polymerase eta [Homo sapiens] [gi:5729982]
View
11
[SID87544714]
IC50 (5% Serum) 78.5A Cell Based Assay for the Characterization of Lead Compounds with Antiviral Activity against HIV-1 (CCR5-Tropic HIV-1 MAGI Antiviral Assay) - Secondary Assay (2) [AID2788, Type: confirmatory]
View
12
[SID87544714]
CC50 91SAR analysis of compounds that inhibit Human Immunodeficiency Virus Fusion, cytoxicity assay [AID435031, Type: confirmatory]
View
13
[SID49826111]
Primary cell-based screen for identification of compounds that inhibit the Choline Transporter (CHT) [AID488975, Type: screening]high affinity choline transporter 1 [Homo sapiens] [gi:11141885]
View
14
[SID49826111]
Potency qHTS for Inhibitors of phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) [AID652105, Type: confirmatory]Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha [gi:18266879]
View
15
[SID49826111]
Single concentration counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay [AID588402, Type: other]phospholipase A2 precursor [Homo sapiens] [gi:4505847]
View
16
[SID49826111]
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of human platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (PAFAH1B2) [AID492953, Type: screening]platelet-activating factor acetylhydrolase IB subunit beta isoform b [Homo sapiens] [gi:296080766]
View
17
[SID49826111]
Fluorescence polarization-based biochemical high throughput confirmation assay for inhibitors of human platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (PAFAH1B2) [AID493034, Type: screening]platelet-activating factor acetylhydrolase IB subunit beta isoform b [Homo sapiens] [gi:296080766]
View
18
[SID49826111]
uHTS fluorescent assay for identification of inhibitors of ATG4B [AID504462, Type: screening]cysteine protease ATG4B isoform a [Homo sapiens] [gi:47132611]
View
19
[SID49826111]
HTS-Luminescent assay for inhibitors of ALR by detection of hydrogen peroxide production Measured in Biochemical System Using Plate Reader - 2036-02_Inhibitor_SinglePoint_HTS [AID485317, Type: screening]FAD-linked sulfhydryl oxidase ALR [Homo sapiens] [gi:54112432]
View
20
[SID49826111]
Confirmatory screen for compounds that inhibit the Choline Transporter (CHT) [AID493221, Type: screening]high affinity choline transporter 1 [Homo sapiens] [gi:11141885]
View