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AGN-PC-04RYAZ (CID 24818907) - Compound BioActivity Data
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BioActivity Outcomes:
Active(13)
 
 
Inactive(515)
 
 
Inconclusive(26)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(21)
 
 
7TM GPCR Srsx(15)
 
 
CAP ED(5)
 
 
TRP 2(5)
 
 
B zip1(4)
 
 
BioAssay Types:
Screening(381)
 
 
 
 
Confirmatory(159)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(122)
 
 
 
 
IC50(28)
 
 
EC50(4)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 496    Data Row: 555   Total Pages: 28   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID49825372]
AbsAC35_uM 24.56Cell-based secondary assay to test the inhibitory activity of small molecule on Plasmodium flaciparum (3D7 strain) survival in red blood cells Measured in Cell-Based System Using Plate Reader - 2120-05_Inhibitor_Dose_CherryPick_Activity [AID652047, Type: confirmatory]
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2
[SID49825372]
AbsAC35_uM 29.09Cell-based secondary assay to test the inhibitory activity of small molecule on Plasmodium flaciparum (HB3 strain) survival in red blood cells Measured in Cell-Based System Using Plate Reader - 2120-06_Inhibitor_Dose_CherryPick_Activity [AID652041, Type: confirmatory]
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3
[SID49825372]
Plate Read Microorganism-Based Primary HTS to Identify Modulators of the AI-2 Quorum Sensing System [AID2094, Type: screening]LuxS, partial [Vibrio harveyi] [gi:166202459]
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4
[SID49825372]
Luminescence Microorganism-Based Retest to Identify Modulators of the AI-2 Quorum Sensing System [AID2736, Type: screening]Chain B, Crystal Structure Of The Apo Form Of Vibrio Harveyi Luxp Complexed With The Periplasmic Domain Of Luxq [gi:67463989]
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5
[SID49825372]
In vivo-based yeast HTS to detect compounds rescuing yeast growth/survival of Plasmodium Falciparum HSP40-mediated toxicity Measured in Whole Organism System Using Plate Reader - 2120-01_Inhibitor_SinglePoint_HTS_Activity [AID504582, Type: screening]HSP40, subfamily A, putative [Plasmodium falciparum 3D7] [gi:124809271]
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6
[SID49825372]
Plate Read Microorganism-Based Primary HTS to Identify Modulators of the AI-2 Quorum Sensing System [AID2094, Type: screening]Chain A, Crystal Structure Of The Apo Form Of Vibrio Harveyi Luxp Complexed With The Periplasmic Domain Of Luxq [gi:67463988]
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7
[SID49825372]
Luminescence Microorganism-Based Retest to Identify Modulators of the AI-2 Quorum Sensing System [AID2736, Type: screening]Chain A, Crystal Structure Of The Apo Form Of Vibrio Harveyi Luxp Complexed With The Periplasmic Domain Of Luxq [gi:67463988]
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8
[SID49825372]
Plate Read Microorganism-Based Primary HTS to Identify Modulators of the AI-2 Quorum Sensing System [AID2094, Type: screening]Chain B, Crystal Structure Of The Apo Form Of Vibrio Harveyi Luxp Complexed With The Periplasmic Domain Of Luxq [gi:67463989]
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9
[SID49825372]
Luminescence Microorganism Retest to Identify Inhibitors of the AI-2 Quorum Sensing System [AID2727, Type: screening]LuxR, partial [Vibrio harveyi] [gi:107933356]
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10
[SID49825372]
Luminescence Microorganism Retest to Identify Inhibitors of the AI-2 Quorum Sensing System [AID2727, Type: screening]Luminescence regulatory protein luxO [gi:160409943]
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11
[SID49825372]
Luminescence Microorganism Retest to Identify Inhibitors of the AI-2 Quorum Sensing System [AID2727, Type: screening]Phosphorelay protein luxU [gi:160409944]
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12
[SID49825372]
Luminescence Microorganism-Based Retest to Identify Modulators of the AI-2 Quorum Sensing System [AID2736, Type: screening]LuxS, partial [Vibrio harveyi] [gi:166202459]
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13
[SID49825372]
Luminescence Microorganism Retest to Identify Inhibitors of the AI-2 Quorum Sensing System [AID2727, Type: screening]Alkanal monooxygenase alpha chain [gi:126509]
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14
[SID49825372]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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15
[SID49825372]
Potency 5.8048A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. [AID624297, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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16
[SID49825372]
Potency 19.9526qHTS Assay for Inhibitors of Influenza NS1 Protein Function [AID2326, Type: confirmatory]nonstructural protein 1 [Influenza A virus (A/WSN/1933(H1N1))] [gi:194352380]
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17
[SID49825372]
Potency 22.3872qHTS Inhibitors of AmpC Beta-Lactamase (assay without detergent) [AID485341, Type: confirmatory]Chain A, Ampc Beta-Lactamase In Complex With 4-Methanesulfonylamino Benzoic Acid [gi:119389684]
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18
[SID49825372]
Potency 35.4813qHTS for Inhibitors of AMA1-RON; Towards Development of Antimalarial Drug Lead: Primary Screen [AID720542, Type: confirmatory]apical membrane antigen 1, AMA1 [Plasmodium falciparum 3D7] [gi:23496270]
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19
[SID49825372]
Potency 79.4328HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails [AID540317, Type: confirmatory]chromobox protein homolog 1 [Homo sapiens] [gi:187960037]
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20
[SID49825372]
Potency 89.1251qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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