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T6158543 (CID 24818215) - Compound BioActivity Data
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BioActivity Outcomes:
Active(5)
 
 
Inactive(523)
 
 
Inconclusive(2)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(37)
 
 
KCNQ channel(8)
 
 
 
CAP ED(5)
 
 
Esterase lipa..(5)
 
 
TRP 2(5)
 
 
BioAssay Types:
Screening(367)
 
 
 
 
Confirmatory(148)
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(114)
 
 
 
 
IC50(28)
 
 
EC50(4)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 485    Data Row: 531   Total Pages: 27   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID49820985]
Primary cell-based high-throughput screening assay for identification of compounds that potentiate/activate KCNQ1 potassium channels [AID2648, Type: screening]potassium voltage-gated channel subfamily KQT member 1 isoform 1 [Homo sapiens] [gi:32479527]
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2
[SID49820985]
Counter screen assay of the parental CHO cells for identification of compounds that potentiate KCNQ1 potassium channels [AID493006, Type: screening]potassium voltage-gated channel subfamily KQT member 1 isoform 1 [Homo sapiens] [gi:32479527]
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3
[SID49820985]
Validation assay for identification of compounds that potentiate KCNQ1 potassium channels [AID493007, Type: screening]potassium voltage-gated channel subfamily KQT member 1 isoform 1 [Homo sapiens] [gi:32479527]
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4
[SID49820985]
Specificity screen assay against KCNQ2 for identification of compounds that potentiate KCNQ1 potassium channels [AID493009, Type: screening]potassium voltage-gated channel subfamily KQT member 2 [Rattus norvegicus] [gi:18959272]
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5
[SID49820985]
Aqueous Solubility from MLSMR Stock Solutions [AID1996, Type: other]
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6
[SID49820985]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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7
[SID49820985]
Potency 11.6891Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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8
[SID49820985]
Potency Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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9
[SID49820985]
Fluorescence-based counterscreen for orexin 1 receptor (OX1R) antagonists: cell-based assay to identify antagonists of the parental CHO cell line [AID463079, Type: screening]
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10
[SID49820985]
uHTS identification of small molecule activators of the adaptive arm of the Unfolded Protein response via a luminescent-based reporter assay [AID463104, Type: screening]
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11
[SID49820985]
Phenotypic HTS multiplex for antifungal efflux pump inhibitors [AID485275, Type: screening]
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12
[SID49820985]
Potency qHTS Assay for Small Molecule Inhibitors of Mitochondrial Division or Activators of Mitochondrial Fusion [AID485298, Type: confirmatory]
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13
[SID49820985]
Inhibitors of Prion Protein 5' UTR mRNA Measured in Cell-Based System Using Plate Reader - 2078-01_Inhibitor_SinglePoint_HTS_Activity [AID488862, Type: screening]
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14
[SID49820985]
IC50 Elucidation of physiology of non-replicating, drug-tolerant Mycobacterium tuberculosis [AID488890, Type: confirmatory]
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15
[SID49820985]
uHTS luminescence assay for the identification of chemical inhibitors of T-cell specific antigen receptor-induced NF-kB activation [AID435003, Type: screening]
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16
[SID49820985]
Luminescence Cell-Based Primary HTS to Identify Inhibitors of Beta Cell Apoptosis. [AID435005, Type: screening]
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17
[SID49820985]
uHTS luminescence assay for the identification of chemical inhibitors of B-cell specific antigen receptor-induced NF-kB activation [AID435022, Type: screening]
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18
[SID49820985]
Counterscreen for inhibitors of AddAB: absorbance-based bacterial cell-based high throughput screening assay to identify inhibitors of bacterial viability [AID449728, Type: screening]
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19
[SID49820985]
IC50 High Throughput Screening Assay used to Identify Novel Compounds that Inhibit Mycobacterium Tuberculosis in 7H9 Media [AID449762, Type: confirmatory]
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20
[SID49820985]
uHTS identification of small molecule activators of the apoptotic arm of the Unfolded Protein response via a luminescent-based reporter assay [AID449763, Type: screening]
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