MLS001079048 (CID 24816860) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(7)
 
 
Inactive(447)
 
 
Inconclusive(2)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(17)
 
 
7TM GPCR Srsx(8)
 
 
TRP 2(5)
 
 
KCNQ channel(4)
 
 
Peptidase C48(4)
 
 
BioAssay Types:
Screening(309)
 
 
 
Confirmatory(137)
 
 
 
 
 
Literature(5)
 
 
BioActivity Types:
Potency(99)
 
 
 
 
 
IC50(30)
 
 
EC50(6)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 457    Data Row: 457   Total Pages: 10   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID87225731]
EC50 0.88SAR analysis of selective Agonists of GPR55 using an Image-Based Assay [AID2347, Type: confirmatory]G-protein coupled receptor 55 [Homo sapiens] [gi:33695107]
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2
[SID49817614]
EC50 0.969209Image-based HTS for Selective Agonists of GPR55 [AID1961, Type: confirmatory]G-protein coupled receptor 55 [Homo sapiens] [gi:33695107]
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3
[SID49817614]
Potency 1.3115Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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4
[SID49817614]
Potency 4.1475Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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5
[SID49817614]
 Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human cholinergic receptor, muscarinic 5 (CHRM5) [AID624040, Type: screening]CHRM5 gene product [Homo sapiens] [gi:7108336]
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6
[SID49817614]
 Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human cholinergic receptor, muscarinic 5 (CHRM5) [AID624040, Type: screening]CHRM5 gene product [Homo sapiens] [gi:7108336]
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7
[SID49817614]
 Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human cholinergic receptor, muscarinic 5 (CHRM5) [AID624040, Type: screening]CHRM5 gene product [Homo sapiens] [gi:7108336]
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8
[SID49817614]
 Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human cholinergic receptor, muscarinic 5 (CHRM5) [AID624040, Type: screening]CHRM5 gene product [Homo sapiens] [gi:7108336]
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9
[SID87225731]
 SAR Analysis for the identification of Selective Agonists of GPR55 using an Image-Based Screen [AID463192, Type: other]G-protein coupled receptor 55 [Homo sapiens] [gi:33695107]
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10
[SID87225731]
 SAR analysis of Agonists of GPR55 using MAPK Activation Assay [AID485279, Type: other]G-protein coupled receptor 55 [Homo sapiens] [gi:33695107]
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11
[SID49817614]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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12
[SID49817614]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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13
[SID49817614]
Potency 11.2202qHTS Inhibitors of AmpC Beta-Lactamase (assay without detergent) [AID485341, Type: confirmatory]Chain A, Ampc Beta-Lactamase In Complex With 4-Methanesulfonylamino Benzoic Acid [gi:119389684]
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14
[SID87225731]
IC50 32SAR analysis of agonists of the Cannabinoid Receptor 1 using an Image-Based Assay [AID2341, Type: confirmatory]Cannabinoid receptor 1 (brain) [Homo sapiens] [gi:71682703]
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15
[SID87225731]
IC50 32SAR analysis of agonists of the Cannabinoid Receptor 1 using an Image-Based Assay [AID2341, Type: confirmatory]Cannabinoid receptor 1 (brain) [Homo sapiens] [gi:71682703]
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16
[SID87225731]
IC50 32SAR analysis of agonists of the Cannabinoid Receptor 1 using an Image-Based Assay [AID2341, Type: confirmatory]Cannabinoid receptor 1 (brain) [Homo sapiens] [gi:71682703]
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17
[SID87225731]
IC50 32SAR analysis of antagonists of the Cannabinoid Receptor 1 using an Image-Based Assay [AID2339, Type: confirmatory]Cannabinoid receptor 1 (brain) [Homo sapiens] [gi:71682703]
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18
[SID87225731]
IC50 32SAR analysis of antagonists of the Cannabinoid Receptor 1 using an Image-Based Assay [AID2339, Type: confirmatory]Cannabinoid receptor 1 (brain) [Homo sapiens] [gi:71682703]
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19
[SID87225731]
IC50 32SAR analysis of antagonists of the Cannabinoid Receptor 1 using an Image-Based Assay [AID2339, Type: confirmatory]Cannabinoid receptor 1 (brain) [Homo sapiens] [gi:71682703]
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20
[SID87225731]
EC50 32SAR analysis of agonists of the Cannabinoid Receptor 2 using an Image-Based Assay - Set 2 [AID434928, Type: confirmatory]cannabinoid receptor 2 [Homo sapiens] [gi:4502929]
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21
[SID87225731]
EC50 32SAR analysis of agonists of the Cannabinoid Receptor 2 using an Image-Based Assay - Set 2 [AID434928, Type: confirmatory]cannabinoid receptor 2 [Homo sapiens] [gi:4502929]
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22
[SID87225731]
EC50 32SAR analysis of agonists of the Cannabinoid Receptor 2 using an Image-Based Assay - Set 2 [AID434928, Type: confirmatory]cannabinoid receptor 2 [Homo sapiens] [gi:4502929]
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23
[SID87225731]
IC50 32SAR analysis of antagonists of the Cannabinoid Receptor 2 using an Image-Based Assay - Set 2 [AID434922, Type: confirmatory]cannabinoid receptor 2 [Homo sapiens] [gi:4502929]
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24
[SID87225731]
IC50 32SAR analysis of antagonists of the Cannabinoid Receptor 2 using an Image-Based Assay - Set 2 [AID434922, Type: confirmatory]cannabinoid receptor 2 [Homo sapiens] [gi:4502929]
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25
[SID87225731]
IC50 32SAR analysis of antagonists of the Cannabinoid Receptor 2 using an Image-Based Assay - Set 2 [AID434922, Type: confirmatory]cannabinoid receptor 2 [Homo sapiens] [gi:4502929]
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26
[SID87225731]
IC50 32SAR analysis of Antagonists of the GPR35 Receptor using an Image-Based Assay [AID2338, Type: confirmatory]G-protein coupled receptor 35 isoform a [Homo sapiens] [gi:33695097]
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27
[SID87225731]
IC50 32SAR analysis of Antagonists of the GPR35 Receptor using an Image-Based Assay [AID2338, Type: confirmatory]G-protein coupled receptor 35 isoform a [Homo sapiens] [gi:33695097]
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28
[SID87225731]
IC50 32SAR analysis of Antagonists of the GPR35 Receptor using an Image-Based Assay [AID2338, Type: confirmatory]G-protein coupled receptor 35 isoform a [Homo sapiens] [gi:33695097]
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29
[SID87225731]
IC50 32SAR analysis of Agonists of the GPR35 Receptor using an Image-Based Assay [AID2340, Type: confirmatory]G-protein coupled receptor 35 isoform a [Homo sapiens] [gi:33695097]
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30
[SID87225731]
IC50 32SAR analysis of Agonists of the GPR35 Receptor using an Image-Based Assay [AID2340, Type: confirmatory]G-protein coupled receptor 35 isoform a [Homo sapiens] [gi:33695097]
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31
[SID87225731]
IC50 32SAR analysis of Agonists of the GPR35 Receptor using an Image-Based Assay [AID2340, Type: confirmatory]G-protein coupled receptor 35 isoform a [Homo sapiens] [gi:33695097]
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32
[SID49817614]
Potency 100qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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33
[SID49817614]
Potency 100qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
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34
[SID49817614]
Potency 100qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
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35
[SID49817614]
 Activator for delta FosB/delta FosB homodimer Measured in Biochemical System Using Plate Reader - 2072-01_Activator_SinglePoint_HTS_Activity [AID493131, Type: screening]protein fosB [Mus musculus] [gi:6679827]
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36
[SID49817614]
 uHTS identification of Gli-Sufu Antagonists in a luminescence reporter assay [AID588413, Type: screening]Gli1 [Mus musculus] [gi:6009644]
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37
[SID49817614]
 uHTS identification of Gli-Sufu Antagonists in a luminescence reporter assay [AID588413, Type: screening]Gli1 [Mus musculus] [gi:6009644]
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38
[SID49817614]
 Luminescence Cell-Based Primary HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1). [AID2098, Type: screening]Hsf1 protein [Mus musculus] [gi:62740231]
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39
[SID49817614]
 Luminescence Cell-Based Primary HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1). [AID2098, Type: screening]Hsf1 protein [Mus musculus] [gi:62740231]
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40
[SID49817614]
 Luminescence-based cell-based primary high throughput screening assay to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A) [AID624169, Type: screening]Htr2a gene product [Mus musculus] [gi:27753985]
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41
[SID49817614]
 Luminescence-based cell-based primary high throughput screening assay to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A) [AID624169, Type: screening]Htr2a gene product [Mus musculus] [gi:27753985]
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42
[SID49817614]
 HTS for developing T Cell Immune Modulators [AID2052, Type: screening]integrin alpha-L [Mus musculus] [gi:124486680]
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43
[SID49817614]
 HTS for developing T Cell Immune Modulators [AID2052, Type: screening]integrin alpha-L [Mus musculus] [gi:124486680]
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44
[SID49817614]
 HTS for developing T Cell Immune Modulators [AID2052, Type: screening]integrin alpha-L [Mus musculus] [gi:124486680]
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45
[SID49817614]
 Primary cell-based high-throughput screening assay for identification of compounds that inhibit/block inward-rectifying potassium ion channel Kir2.1 [AID1672, Type: screening]inward rectifier potassium channel 2 [Mus musculus] [gi:6680530]
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46
[SID49817614]
IC50 Fluorescence for the identification of compounds that decrease p/CIP protein stability [AID1984, Type: confirmatory]nuclear receptor coactivator 3 [Mus musculus] [gi:118026946]
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47
[SID49817614]
 Fluorescence polarization-based biochemical primary high throughput screening assay to identify activators of the Protein Kinase A-R1A (PKA-R1A) complex [AID504707, Type: screening]cAMP-dependent protein kinase catalytic subunit beta isoform 1 [Mus musculus] [gi:6755076]
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48
[SID49817614]
Potency qHTS for Inhibitors of Cell Surface uPA Generation [AID540303, Type: confirmatory]urokinase-type plasminogen activator [Mus musculus] [gi:6679377]
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49
[SID49817614]
Potency qHTS for Inhibitors of Cell Surface uPA Generation [AID540303, Type: confirmatory]urokinase-type plasminogen activator [Mus musculus] [gi:6679377]
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50
[SID49817614]
Potency qHTS for inhibitors of ROR gamma transcriptional activity [AID2551, Type: confirmatory]nuclear receptor ROR-gamma [Mus musculus] [gi:188536040]
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