Bookmark and Share
MLS000882722 (CID 24789347) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(34)
 
 
Inactive(518)
 
 
Inconclusive(18)
 
 
Unspecified(2)
 
 
Top Targets:
7tm 4(38)
 
 
 
Peptidase C48(11)
 
 
 
ANK(6)
 
 
 
TRP 2(5)
 
 
Esterase lipa..(5)
 
 
BioAssay Types:
Screening(382)
 
 
 
 
Confirmatory(175)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(133)
 
 
 
 
 
IC50(31)
 
 
 
EC50(4)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 507    Data Row: 572   Total Pages: 29   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID49713967]
Potency 1.4125qHTS Assay for Inhibitors of Hepatitis C Virus (HCV) [AID651820, Type: confirmatory]
View
2
[SID124898586]
Potency 2.8184qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
3
[SID49713967]
AbsAC1000_uM 4.341In vivo-based yeast HTS to detect compounds rescuing yeast growth/survival of Plasmodium Falciparum HSP40-mediated toxicity Measured in Whole Organism System Using Plate Reader - 2120-01_Inhibitor_Dose_CherryPick_Activity [AID540271, Type: confirmatory]HSP40, subfamily A, putative [Plasmodium falciparum 3D7] [gi:124809271]
View
4
[SID49713967]
IC50_Mean 5.67Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 7 (SENP7) using a Luminescent assay [AID488904, Type: confirmatory]SUMO1/sentrin specific peptidase 7 [Homo sapiens] [gi:120538355]
View
5
[SID49713967]
Potency 7.3078qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
6
[SID49713967]
Potency 7.3078qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
7
[SID49713967]
Potency 10VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity [AID2546, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
View
8
[SID49713967]
Potency 13.4591qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) [AID588342, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
View
9
[SID49713967]
IC50_Mean 19.5Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 6 (SENP6) using a Luminescent assay [AID488921, Type: confirmatory]SUMO-1-specific protease [Homo sapiens] [gi:6166485]
View
10
[SID49713967]
IC50_Mean 23.9Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay [AID488903, Type: confirmatory]sentrin-specific protease 8 [Homo sapiens] [gi:262118306]
View
11
[SID49713967]
IC50_Mean 32.3Dose Response confirmation of inhibitors of Sentrin-specific proteases (SENPs) using a Caspase-3 Selectivity assay [AID488901, Type: confirmatory]caspase-3 preproprotein [Homo sapiens] [gi:14790119]
View
12
[SID49713967]
AbsAC35_uM 40.27Cell-based secondary assay to test the inhibitory activity of small molecule on Plasmodium flaciparum (HB3 strain) survival in red blood cells Measured in Cell-Based System Using Plate Reader - 2120-06_Inhibitor_Dose_CherryPick_Activity [AID652041, Type: confirmatory]
View
13
[SID49713967]
MLPCN Alpha-Synuclein 5'UTR - 5'-UTR binding - activators [AID1814, Type: screening]
View
14
[SID49713967]
Fluorescence-based primary cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7). [AID1861, Type: screening]neuropeptides B/W receptor 1 [Homo sapiens] [gi:119607128]
View
15
[SID49713967]
Fluorescence-based confirmation cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7). [AID1952, Type: screening]neuropeptides B/W receptor 1 [Homo sapiens] [gi:119607128]
View
16
[SID49713967]
Single concentration confirmation of uHTS inhibitor hits of the mitochondrial permeability transition pore via a fluorescent based assay [AID624504, Type: screening]
View
17
[SID49713967]
uHTS identification of small molecule inhibitors of the mitochondrial permeability transition pore via an absorbance assay [AID602449, Type: screening]
View
18
[SID49713967]
Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of COUP-TFII (NR2F2) [AID686940, Type: screening]COUP transcription factor 2 isoform a [Homo sapiens] [gi:14149746]
View
19
[SID49713967]
uHTS Luminescent assay for identification of inhibitors of Sentrin-specific protease 6 (SENP6) [AID2599, Type: screening]SUMO-1-specific protease [Homo sapiens] [gi:6166485]
View
20
[SID49713967]
Single concentration confirmation of uHTS for inhibitors of Sentrin-specific protease 6 (SENP6) using a Luminescent assay [AID488915, Type: screening]SUMO-1-specific protease [Homo sapiens] [gi:6166485]
View