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MLS001215963 (CID 24761173) - Compound BioActivity Data
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BioActivity Outcomes:
Active(35)
 
 
Inactive(471)
 
 
Inconclusive(14)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(19)
 
 
7TM GPCR Srsx(15)
 
 
UBCc(8)
 
 
 
Hexokinase 2(6)
 
 
 
TRP 2(5)
 
 
BioAssay Types:
Screening(333)
 
 
 
Confirmatory(174)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(117)
 
 
 
 
 
IC50(45)
 
 
 
EC50(6)
 
 
 
AC50(3)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 462    Data Row: 521   Total Pages: 27   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID49667379]
IC50 5.82AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation [AID2018, Type: confirmatory]SUMO-conjugating enzyme UBC9 [Homo sapiens] [gi:4507785]
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2
[SID49667379]
IC50 5.82AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation [AID2018, Type: confirmatory]Ubiquitin-like modifier activating enzyme 2 [Homo sapiens] [gi:13111961]
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3
[SID49667379]
IC50 5.82AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation [AID2018, Type: confirmatory]SUMO1 activating enzyme subunit 1 [Homo sapiens] [gi:17390638]
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4
[SID87544853]
IC50_Mean 7.97SAR analysis of the MOA of E2 SUMOylation inhibitors in an HTRF format [AID485393, Type: confirmatory]Ubiquitin-like modifier activating enzyme 2 [Homo sapiens] [gi:13111961]
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5
[SID87544853]
IC50_Mean 7.97SAR analysis of the MOA of E2 SUMOylation inhibitors in an HTRF format [AID485393, Type: confirmatory]SUMO1 activating enzyme subunit 1 [Homo sapiens] [gi:17390638]
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6
[SID87544853]
IC50_Mean 7.97SAR analysis of the MOA of E2 SUMOylation inhibitors in an HTRF format [AID485393, Type: confirmatory]SUMO-conjugating enzyme UBC9 [Homo sapiens] [gi:4507785]
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7
[SID49667379]
IC50 9.097QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) [AID1890, Type: confirmatory]3C-like protease [Infectious bronchitis virus] [gi:73745819]
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8
[SID49667379]
IC50_Mean 9.43Dose Response confirmation of inhibitors of hexokinase domain containing I (HKDC1) [AID504729, Type: confirmatory]putative hexokinase HKDC1 [Homo sapiens] [gi:156151420]
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9
[SID49667379]
Potency 10qHTS Assay for Inhibitors of BAZ2B [AID504333, Type: confirmatory]bromodomain adjacent to zinc finger domain 2B [Homo sapiens] [gi:6683500]
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10
[SID49667379]
EC50_uM 12.1Fluorescence Cell-Free Homogeneous Dose Retest to Identify Inhibitors of RecA-Intein Splicing Activity [AID435010, Type: confirmatory]RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)] [Mycobacterium tuberculosis H37Rv] [gi:15609874]
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11
[SID49667379]
AC50_uM 12.31Fluorescence Cell-Free Homogeneous Secondary Screen to Identify Inhibitors of DnaB-Intein Splicing Activity [AID449749, Type: confirmatory]Probable replicative DNA helicase DnaB [Mycobacterium tuberculosis H37Rv] [gi:15607200]
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12
[SID49667379]
IC50 12.35uHTS HTRF assay for identification of inhibitors of SUMOylation [AID2006, Type: confirmatory]Ubiquitin-like modifier activating enzyme 2 [Homo sapiens] [gi:13111961]
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13
[SID49667379]
IC50 12.35uHTS HTRF assay for identification of inhibitors of SUMOylation [AID2006, Type: confirmatory]SUMO1 activating enzyme subunit 1 [Homo sapiens] [gi:17390638]
View
14
[SID49667379]
IC50 12.35uHTS HTRF assay for identification of inhibitors of SUMOylation [AID2006, Type: confirmatory]SUMO-conjugating enzyme UBC9 [Homo sapiens] [gi:4507785]
View
15
[SID87544853]
IC50_Mean 13.4SAR analysis of SUMOylation using HTRF in an in-Vitro dose response assay [AID2614, Type: confirmatory]SUMO-conjugating enzyme UBC9 [Homo sapiens] [gi:4507785]
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16
[SID87544853]
IC50_Mean 13.4SAR analysis of SUMOylation using HTRF in an in-Vitro dose response assay [AID2614, Type: confirmatory]SUMO1 activating enzyme subunit 1 [Homo sapiens] [gi:17390638]
View
17
[SID87544853]
IC50_Mean 13.4SAR analysis of SUMOylation using HTRF in an in-Vitro dose response assay [AID2614, Type: confirmatory]Ubiquitin-like modifier activating enzyme 2 [Homo sapiens] [gi:13111961]
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18
[SID49667379]
AC50_uM 15.99VEID(2) R110 Enzymatic Primary HTS to identify Inhibitors of Caspase 6 Measured in Biochemical System Using Plate Reader - 7052-01_Inhibitor_Dose_CherryPick_Activity [AID720632, Type: confirmatory]Caspase 6, apoptosis-related cysteine peptidase [Homo sapiens] [gi:13325293]
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19
[SID49667379]
Potency 22.3872qHTS Assay for Inhibitors of JMJD2A-Tudor Domain [AID504339, Type: confirmatory]Chain A, Jmjd2a Tandem Tudor Domains In Complex With A Trimethylated Histone H4-K20 Peptide [gi:162330054]
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20
[SID49667379]
Potency 31.6228qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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